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内部出版物
NATURE电子期刊(1)
Elsevier电子期刊(5)
ACS电子期刊(6)
在“
Elsevier电子期刊
”中,
命中:
5
条,耗时:小于0.01 秒
在所有数据库中总计命中:
12
条
1.
Novel GlyT1 inhibitor chemotypes by scaffold hopping. Part 1: Development of a potent and CNS penetrant [3.1.0]-based lead
作者:
Carrie K. Jones
;
Douglas J. Sheffler
;
Richard Williams
;
Sataya B. Jadhav
;
Andrew
S.
Felts
;
Ryan D. Morrison
;
Colleen M. Niswender
;
J. Scott Daniels
;
P. Jeffrey Conn
;
Craig W. Lindsley
关键词:
GlyT1
;
Scaffold hopping
;
Transporter
;
Schizophrenia
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:15 February, 2014
2.
Discovery of VU0409106: A negative allosteric modulator of mGlu
5
with activity in a mouse model of anxiety
作者:
Andrew
S.
Felts
;
Alice L. Rodriguez
;
Ryan D. Morrison
;
Daryl F. Venable
;
Jason T. Manka
;
Brittney S. Bates
;
Anna L. Blobaum
;
Frank W. Byers
;
J. Scott Daniels
;
Colleen M. Niswender
;
Carrie K. Jones
;
P. Jeffrey Conn
;
Craig W. Lindsley
;
Kyle A. Emmitte
关键词:
Glutamate
;
CNS
;
mGlu5
;
Allosteric modulator
;
Anxiety
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2013
3.
3-Cyano-5-fluoro-N-arylbenzamides as negative allosteric modulators of mGlu
5
: Identification of easily prepared tool compounds with CNS exposure in rats
作者:
Andrew
S.
Felts
;
Stacey R. Lindsley
;
Jeffrey P. Lamb
;
Alice L. Rodriguez
;
Usha N. Menon
;
Satyawan Jadhav
;
Carrie K. Jones
;
P. Jeffrey Conn
;
Craig W. Lindsley
;
Kyle A. Emmitte
关键词:
mGlu5
;
GPCR
;
Allosteric modulator
;
CNS
;
GERD
;
Fragile X syndrome
;
Addiction
;
PD-LID
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2010
4.
The influence of double bond geometry in the inhibition of cyclooxygenases by sulindac derivatives
作者:
Matthew J. Walters
;
Anna L. Blobaum
;
Philip J. Kingsley
;
Andrew
S.
Felts
;
Gary A. Sulikowski
;
Lawrence J. Marnett
关键词:
COX inhibition
;
Photoisomerization
;
NSAIDs
;
2′
;
-
des
-Methyl sulindac sulfide
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2009
5.
Discovery and SAR of 6-substituted-4-anilinoquinazolines as non-competitive antagonists of mGlu
5
作者:
Andrew
S.
Felts
;
Sam A. Saleh
;
Uyen Le
;
Alice L. Rodriguez
;
C. David Weaver
;
P. Jeffrey Conn
;
Craig W. Lindsley
;
Kyle A. Emmitte
关键词:
Glutamate
;
Metabotropic glutamate receptor 5
;
Negative allosteric modulator
;
Non-competitive antagonist
;
Quinazoline
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2009
1
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