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Wiley电子期刊(8)	NATURE电子期刊(3)	ACS电子期刊(86)
SpringerLink电子期刊(107)	Elsevier电子期刊(230)

在“Elsevier电子期刊”中，命中：230条，耗时：0.0429786 秒

在所有数据库中总计命中：434条

1.Drug-to-antibody determination for an antibody-drug-conjugate utilizing cathepsin B digestion coupled with reversed-phase high-pressure liquid chromatography analysis

作者：Michael Adamo^a ; ^{michael.adamo@bms.com} ; Guoyong Sun^a ; Difei Qiu^b ; Joseph Valente^b ; Wenkui Lan^b ; Hangtian Song^a ; Mark Bolgar^b ; Amit Katiyar^a ; Girija Krishnamurthy^a

关键词：Cathepsin B ; DAR ; Drug to antibody ratio ; ADC ; Antibody drug conjugate

刊名：Journal of Chromatography A

出版年：2017

2.Antibody-drug conjugate directed against the guanylyl cyclase antigen for the treatment of gastrointestinal malignancies

作者：Khaldoun Almhanna^a ; ^{Khaldoun.almhanna@moffitt.org} ; Gopi K. Prithviraj^a ; Petter Veiby^b ; Thea Kalebic^c

关键词：Antibody&ndash ; drug conjugate ; Guanylyl cyclase C ; GI malignancies

刊名：Pharmacology & Therapeutics

出版年：2017

3.Phase 1/2 Study of the CD56-Targeting Antibody-Drug Conjugate Lorvotuzumab Mertansine (IMGN901) in Combination With Carboplatin/Etoposide in Small-Cell Lung Cancer Patients With Extensive-Stage Disease

作者：Mark A. Socinski¹ ; ^{socinskima@upmc.edu} ; Frederic J. Kaye² ; David R. Spigel³ ; Fred J. Kudrik⁴ ; Santiago Ponce⁵ ; Peter M. Ellis⁶ ; Margarita Majem⁷ ; Paul Lorigan⁸ ; Leena Gandhi⁹ ; Martin E. Gutierrez¹⁰ ; Dale Nepert¹¹ ; Jesus Corral⁵ ; Luis Paz Ares⁵

关键词：Clinical trial ; Combination therapy ; SCLC ; Targeted drug delivery ; Tolerability

刊名：Clinical Lung Cancer

出版年：2017

4.Optimization of non-linear gradient in hydrophobic interaction chromatography for the analytical characterization of antibody-drug conjugates

作者：Balá ; zs Bobá ; ly ; Giuseppe Marco Randazzo ; Serge Rudaz ; Davy Guillarme ; Szabolcs Fekete ; ^{szabolcs.fekete@unige.ch}

关键词：Hydrophobic interaction chromatography ; Antibody-drug-conjugate ; Method development ; Retention modelling ; Non-linear gradient

刊名：Journal of Chromatography A

出版年：2017

5.Rovalpituzumab tesirine, a DLL3-targeted antibody-drug conjugate, in recurrent small-cell lung cancer: a first-in-human, first-in-class, open-label, phase 1 study

作者：Prof Charles M Rudin ; MD^a ; ^{rudinc@mskcc.org} ; M Catherine Pietanza ; MD^a ; Todd M Bauer ; MD^b ; ^c ; Prof Neal Ready ; MD^d ; Daniel Morgensztern ; MD^e ; Prof Bonnie S Glisson ; MD^f ; Lauren A Byers ; MD^f ; Melissa L Johnson ; MD^b ; ^c ; Howard A Burris III ; MD^b ; ^c ; Prof Francisco Robert ; MD^g ; Tae H Han ; PhDⁱ ; Sheila Bheddah ; BAⁱ ; Noah Theiss ; MS^h ; Sky Watson ; BS^h ; Deepan Mathur ; MD^h ; Bharathi Vennapusa ; MD^h ; Hany Zayed ; PhDⁱ ; Satwant Lally ; MSⁱ ; Donald K Strickland ; MD^c ; Prof Ramaswamy Govindan ; MD^e ; Scott J Dylla ; PhDⁱ ; Stanford L Peng ; MDⁱ ; David R Spigel ; MD^b ; ^c ; for the SCRX16-001 investigators^&dagger ;

刊名：The Lancet Oncology

出版年：2017

6.An antigen-encapsulating nanoparticle platform for T_H1/17 immune tolerance therapy

作者：Derrick P. McCarthy ; PhD^a ; ¹ ; Jonathan Woon-Teck Yap ; PhD^b ; ¹ ; Christopher T. Harp ; PhD^a ; ¹ ; W. Kelsey Song ; BS^c ; Jeane Chen ; PhD^c ; Ryan M. Pearson ; PhD^g ; Stephen D. Miller ; PhD^a ; ^d ; ^e ; ^{s-d-miller@northwestern.edu} ; Lonnie D. Shea ; PhD^b ; ^c ; ^d ; ^e ; ^f ; ^g ; ^h ; ^{ldshea@umich.edu}

关键词：Nanoparticle ; Immune tolerance ; Autoimmune disease ; Drug delivery

刊名：Nanomedicine: Nanotechnology, Biology and Medicine

出版年：2017

7.Antibody-drug conjugate characterization by chromatographic and electrophoretic techniques

作者：Tao Chen^a ; Yan Chen^b ; Cinzia Stella^b ; Colin D. Medley^a ; Jason A. Gruenhagen^a ; Kelly Zhang^a ; ^{zhang.kelly@gene.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Antibody drug conjugate (ADC) ; Critical quality attribute (CQA) ; Drug-to-antibody ratio (DAR) ; Drug distribution ; Peptide mapping ; Charge variants ; Aggregations ; Free drug analysis

刊名：Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences

出版年：2016

8.Structural characterization of antibody drug conjugate by a combination of intact, middle-up and bottom-up techniques using sheathless capillary electrophoresis - Tandem mass spectrometry as nanoESI infusion platform and separation method

作者：Nassur Said^a ; Rabah Gahoual^a ; ^b ; Lauriane Kuhn^c ; Alain Beck^d ; Yannis-Nicolas Franç ; ois^a ; ^{yfrancois@unistra.fr" class="auth_mail" title="E-mail the corresponding author} ; Emmanuelle Leize-Wagner^a

关键词：Sheathless capillary electrophoresis-mass spectrometry ; Antibody-drug conjugate ; vcMMAE-ADC ; Drug to antibody ratio ; Drug-loaded peptides

刊名：Analytica Chimica Acta

出版年：2016

9.Regression of metastatic, radiation/chemotherapy-resistant uterine serous carcinoma overexpressing HER2/neu with trastuzumab emtansine (TDM-1)

作者：Alessandro D. Santin^a ; ^{alessandro.santin@yale.edu} ; Stefania Bellone^a ; Natalia Buza^b ; Peter E. Schwartz^a

关键词：Uterine serous carcinoma ; Trastuzumab-emtansine ; HER2/neu

刊名：Gynecologic Oncology Reports

出版年：2017

10.Multiple heart-cutting and comprehensive two-dimensional liquid chromatography hyphenated to mass spectrometry for the characterization of the antibody-drug conjugate ado-trastuzumab emtansine

作者：Koen Sandra^a ; ^{koen.sandra@richrom.com" class="auth_mail" title="E-mail the corresponding author} ; Gerd Vanhoenacker^a ; Isabel Vandenheede^a ; Mieke Steenbeke^a ; Maureen Joseph^b ; Pat Sandra^a

关键词：Antibody-drug conjugate ; Ado-trastuzumab emtansine ; Two-dimensional liquid chromatography ; Multiple heart-cutting ; Comprehensive

刊名：Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences

出版年：2016

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