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SpringerLink电子期刊(6)
Elsevier电子期刊(71)
ACS电子期刊(12)
在“
Elsevier电子期刊
”中,
命中:
71
条,耗时:小于0.01 秒
在所有数据库中总计命中:
89
条
1.
A novel microdialysis-dissolution/permeation system for testing oral dosage forms: A proof-of-concept study
作者:
Sophia Yui Kau Fong
;
Jessie Poulsen
;
Martin Brandl
;
Annette Bauer-Brandl
;
annette.bauer@sdu.dk
关键词:
D/P system
;
dissolution/permeation system
;
DSC
;
differential scanning calorimetry
;
FaSSIF
;
fasted state simulated intestinal fluid
;
HCS
;
hydrocortisone
;
IS
;
internal standard
;
Jss
;
steady-state flux
;
LLOD
;
lower limit of detection
;
LLOQ
;
lower limit of quantification
;
M-D/P system
;
microdialysis-dissolution/permeation system
;
MWCO
;
molecular weight cut-off
;
PBS
;
phosphate buffer saline
;
QC
;
quality control
;
RSD
;
relative standard deviation
;
UHPLC-UV
;
Ultra-High-Performance Liquid Chromatography-
刊名:European Journal of Pharmaceutical Sciences
出版年:2017
2.
Dissolution behavior of co-amorphous amino acid-indomethacin mixtures: The ability of amino acids to stabilize the supersaturated state of indomethacin
作者:
Rami Ojarinta
a
;
rami.ojarinta@uef.fi
;
Aki T. Heikkinen
b
;
a
;
Elina Sievä
;
nen
c
;
Riikka Laitinen
a
关键词:
AA
;
amino acid
;
ACN
;
acetonitrile
;
ARG
;
arginine
;
AUC
;
area under the curve
;
CA
;
co-amorphous
;
DMSO
;
dimethyl sulfoxide
;
DS
;
degree of supersaturation
;
DSC
;
differential scanning calorimetry
;
EGF
;
excipient gain factor
;
FaSSIF
;
fasted state simulated intestinal fluid
;
FeSSIF
;
fed state simulated intestinal fluid
;
FTIR
;
Fourier transform infrared spectroscopy
;
HPLC
;
high performance liquid chromatography
;
IND
;
indomethacin
;
PHE
;
phenylalanine
;
PM
;
physical mixture
;
SF
;
supersaturation factor
;
ssN
刊名:European Journal of Pharmaceutics and Biopharmaceutics
出版年:2017
3.
Theoretical Analysis of Drug Dissolution in Micellar Media
作者:
Boris Shekunov
;
bshekunov@shire.com
关键词:
equilibrium solubility and intrinsic dissolution rate
;
active pharmaceutical ingredients
;
rotating disk apparatus
;
drug particles
;
diffusion and surface dissolution kinetics
;
biologically relevant media
;
FaSSIF
;
FeSSIF
;
micelles
;
surfactants
刊名:Journal of Pharmaceutical Sciences
出版年:2017
4.
Statistical investigation of simulated fed intestinal media composition on the equilibrium solubility of oral drugs
作者:
Zhou Zhou
;
Claire Dunn
;
Ibrahim Khadra
;
Clive G. Wilson
;
Gavin W. Halbert
;
g.w.halbert@strath.ac.uk
关键词:
BCS
;
Biopharmaceutics Classification System
;
DoE
;
Design of Experiment
;
FASSIF
;
Fasted Simulated Intestinal Fluid
;
FESSIF
;
Fed Simulated Intestinal Fluid
;
IVIVC
;
In vitro In vivo correlation
刊名:European Journal of Pharmaceutical Sciences
出版年:2017
5.
Evaluation of different in vitro dissolution tests based on level A in vitro-in vivo correlations for fenofibrate self-emulsifying lipid-based formulations
作者:
Aude Pestieau
a
;
Aude.Pestieau@ulg.ac.be
;
Sonia Lebrun
b
;
Bernard Cahay
b
;
Adeline Brouwers
b
;
Bruno Streel
b
;
Jean-Michel Cardot
c
;
Brigitte Evrard
a
关键词:
Af
;
absorbed API fraction without EHC
;
API
;
Active Pharmaceutical Ingredient
;
AUC
;
Area Under the Curve
;
BCS
;
Biopharmaceutics Classification System
;
Cmax
;
Maximal Concentration
;
CS
;
Saturation Concentration
;
DSC
;
Differential Scanning Calorimetry
;
EHC
;
EnteroHepatic Circulation
;
EMA
;
European Medicines Agency
;
FaSSGF
;
Fasted State Simulated Gastric Fluid
;
FaSSIF
;
Fasted State Simulated Intestinal Fluid
;
FDA
;
Food and Drug Administration
;
FeSSIF
;
Fed State Simulated Intestinal Fluid
;
GIT
;
Gastro
刊名:European Journal of Pharmaceutics and Biopharmaceutics
出版年:2017
6.
Comparison of 2 strategies to enhance pyridoclax solubility: Nanoemulsion delivery system versus salt synthesis
作者:
A.-C. Groo
;
M. De Pascale
;
A.-S. Voisin-Chiret
;
anne-sophie.voisin@unicaen.fr
;
S. Corvaisier
;
M. Since
;
A. Malzert-Fré
;
on
;
aurelie.malzert-freon@unicaen.fr
关键词:
Oligopyridine
;
Nanoemulsions
;
Solubility enhancement
;
Biomimetic media
;
Preclinical studies
刊名:European Journal of Pharmaceutical Sciences
出版年:2017
7.
FaSSIF
-V3, but not compendial media, appropriately detects differences in the peak and extent of exposure between reference and test formulations of ibuprofen
作者:
Rodrigo Cristofoletti
a
;
b
;
Jennifer B. Dressman
b
;
dressman@em.uni-frankfurt.de" class="auth_mail" title="E-mail the corresponding author
关键词:
Dissolution
;
Surface pH
;
Biopharmaceutics Classification System (BCS)
;
Capacity of detection
;
Biowaiver
刊名:European Journal of Pharmaceutics and Biopharmaceutics
出版年:2016
8.
Does the commonly used pH-stat method with back titration really quantify the enzymatic digestibility of lipid drug delivery systems? A case study on solid lipid nanoparticles (SLN)
作者:
Martha Heider
a
;
martha.heider@pharmazie.uni-halle.de
;
Gerd Hause
b
;
gerd.hause@biozentrum.uni-halle.de
;
Karsten Mä
;
der
a
;
maeder@pharmazie.uni-halle.de
关键词:
CEH
;
carboxyl ester hydrolase
;
cmc
;
critical micelle concentration
;
CP
;
cetyl palmitate
;
FA
;
fatty acids
;
FaSSIF
;
fasted state simulating medium
;
FeSSIF
;
fed state simulating medium
;
GIT
;
gastrointestinal tract
;
HPTLC
;
high performance thin layer chromatography
;
LBDDS
;
lipid based drug delivery systems
;
P188
;
poloxamer 188
;
PDI
;
polydispersity index
;
PS80
;
polysorbate 80
;
SLN
;
solid lipid nanoparticles
刊名:European Journal of Pharmaceutics and Biopharmaceutics
出版年:2016
9.
PLGA nanoparticles for peroral delivery: How important is pancreatic digestion and can we control it?
作者:
Anika Mante
1
;
2
;
anika.mante@medizin.uni-leipzig.de" class="auth_mail" title="E-mail the corresponding author
;
Martha Heider
1
;
martha.heider@pharmazie.uni-halle.de" class="auth_mail" title="E-mail the corresponding author
;
Christin Zlomke
christin.zlomke@pharmazie.uni-halle.de" class="auth_mail" title="E-mail the corresponding author
;
Karsten Mä
;
der
;
Maeder@pharmazie.uni-halle.de" class="auth_mail" title="E-mail the corresponding author
关键词:
FaSSIF
;
fasted state simulated intestinal fluid
;
FeSSIF
;
simulated state intestinal fluid
;
NPs
;
nanoparticles
;
PDI
;
polydispersity index
;
PEG-PLA
;
pegylated poly(lactic acid)
;
PLA
;
poly(lactic acid)
;
PLGA
;
poly(lactideglycolic acid)
;
PVA
;
Poly(vinyl alcohol)
;
Tris
;
tris(hydroxymethyl)-aminomethan
;
z-aver
;
z-average
刊名:European Journal of Pharmaceutics and Biopharmaceutics
出版年:2016
10.
Design, synthesis, and evaluation of novel porcupine inhibitors featuring a fused 3-ring system based on the ‘reversed’ amide scaffold
作者:
Zhixiang Xu
a
;
&dagger
;
;
Xiangxiang Xu
a
;
&dagger
;
;
Ruadhan O&rsquo
;
Laoi
b
;
Haikuo Ma
a
;
Jiyue Zheng
a
;
jyzheng@suda.edu.cn" class="auth_mail" title="E-mail the corresponding author
;
Shuaishuai Chen
c
;
Lusong Luo
c
;
lusong.luo@beigene.com" class="auth_mail" title="E-mail the corresponding author
;
Zhilin Hu
d
;
Sudan He
d
;
Jiajun Li
a
;
Hongjian Zhang
a
;
Xiaohu Zhang
a
;
xiaohuzhang@suda.edu.cn" class="auth_mail" title="E-mail the corresponding author
关键词:
BPO
;
benzoyl peroxide
;
DCM
;
dichloromethane
;
DIPEA
;
N
;
N-diisopropylethylamine
;
DMF
;
N
;
N-dimethylformamide
;
DMSO
;
dimethyl sulfoxide
;
FaSSIF
;
fasted state simulated intestinal fluid
;
HATU
;
1-[bis(dimethylamino)methylene]-1H-1
2 ;
3-triazolo[4
;
5-b]pyridinium 3-oxid hexafluorophosphate
;
SEM
;
standard error measurement
;
SGF
;
simulated gastric fluid
;
STF
;
super-top flash
;
TFA
;
trifluoroacetic acid
刊名:Bioorganic & Medicinal Chemistry
出版年:2016
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