搜索页_Histone deacetylase (HDAC) inhibitors

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Wiley电子期刊(27)	NATURE电子期刊(12)	ACS电子期刊(142)
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在“Elsevier电子期刊”中，命中：879条，耗时：0.0159912 秒

在所有数据库中总计命中：1,437条

1.Design, synthesis and evaluation of antiproliferative activity of melanoma-targeted histone deacetylase inhibitors

作者：Idris Raji^a ; Kabir Ahluwalia^a ; Adegboyega K. Oyelere^a ; ^b ; ^{aoyelere@gatech.edu}

关键词：HDAC ; histone deacetylase ; HDACi ; histone deacetylase inhibitors ; ZBG ; zinc binding group

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

2.Histone deacetylases inhibitors (HDACis) as novel therapeutic application in various clinical diseases

作者：Xiaoyan Qiu ; Xiong Xiao ; Nan Li ; Yuemin Li ; ^{lym@swu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：HAT ; histone acetyltransferases ; HSP70 ; heat shock protein 70 ; GDNF ; glial cell line-derived neurotrophic factor ; BDNF ; brain derived neurotrophic factor ; SMN ; survival motor neuron ; FMR ; fragile X mental retardation ; iNOS ; inducible nitric oxide synthase ; MMP-9 ; matrix metalloproteinase-9 ; MIP-1 ; macrophage inflammatory protein-1 ; MCP-1 ; monocyte chemoattractant protein-1 ; IGFBP-3 ; insulin-like growth factors binding protein-3 ; PCNA ; proliferating cell nuclear antigen ; FADD ; fas associated deat

刊名：Progress in Neuropsychopharmacology & Biological Psychiatry

出版年：2017

3.Tescalcin is a potential target of class I histone deacetylase inhibitors in neurons

作者：Gakuya Takamatsu^a ; ^b ; Chiaki Katagiri^a ; ^c ; Tsumuraya Tomoyuki^a ; Chigusa Shimizu-Okabe^d ; Wakako Nakamura^a ; Mariko Nakamura-Higa^a ; Tomoko Hayakawa^a ; Shigeo Wakabayashi^e ; Tsuyoshi Kondo^b ; Chitoshi Takayama^d ; Masayuki Matsushita^a ; ^{masayuki@med.u-ryukyu.ac.jp}

关键词：Tescalcin ; Calcineurin B homologous protein ; Histone deacetylase ; Valproate acid ; Trichostatin A ; Suberoylanilide hydroxamic acid

刊名：Biochemical and Biophysical Research Communications

出版年：2017

4.Bifunctional conjugates with potent inhibitory activity towards cyclooxygenase and histone deacetylase

作者：Idris Raji^a ; Fatima Yadudu^a ; Emily Janeira^e ; Shaghayegh Fathi^a ; Lindsey Szymczak^c ; James Richard Kornacki^c ; Kensei Komatsu^d ; Jian-Dong Li^d ; Milan Mrksich^c ; Adegboyega K. Oyelere^a ; ^b ; ^{aoyelere@gatech.edu}

关键词：HDAC ; histone deacetylase ; HDACi ; histone deacetylase inhibitors ; COX ; cyclooxygenases ; NSAIDs ; non-steroidal anti-inflammatory drugs ; AR ; androgen receptor ; ZBG ; zinc binding group ; PGE2 ; prostaglandin E2

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

5.A naturally occurring mixture of tocotrienols inhibits the growth of human prostate tumor, associated with epigenetic modifications of cyclin-dependent kinase inhibitors p21 and p27

作者：Ying Huang^a ; ¹ ; Renyi Wu^a ; ¹ ; Zheng-Yuan Su^a ; ^c ; Yue Guo^a ; Xi Zheng^b ; Chung S. Yang^b ; Ah-Ng Kong^a ; ^{KongT@pharmacy.rutgers.edu}

关键词：T3 ; tocotrienol ; T ; tocopherol ; HDAC ; histone deacetylase ; HAT ; histone acetyltransferase ; CDK ; cyclin-dependent kinase

刊名：The Journal of Nutritional Biochemistry

出版年：2017

6.Ring-opened tetrahydro-γ-carbolines display cytotoxicity and selectivity with histone deacetylase isoforms

作者：Kunal Nepali^a ; ¹ ; Hsueh-Yun Lee^a ; ¹ ; Mei-Jung Lai^b ; Ritu Ojha^a ; Tung-Yun Wu^c ; Gu-Xian Wu^a ; Mei-Chuan Chen^c ; ^{mcchen1250@tmu.edu.tw} ; Jing-Ping Liou^a ; ^d ; ^{jpl@tmu.edu.tw}

关键词：Anticancer agents ; Histone deacetylase inhibitors

刊名：European Journal of Medicinal Chemistry

出版年：2017

7.Design and synthesis of benzodiazepine analogs as isoform-selective human lysine deacetylase inhibitors

作者：D. Rajasekhar Reddy ; Flavio Ballante ; Nancy J. Zhou ; Garland R. Marshall ; ^{garlandm@gmail.com}

关键词：Epigenetics ; Histone deacetylase (HDAC) ; Lysine deacetylase (KDAC) ; Benzodiazepine (BZD) ; Structure-based drug design (SBDD)

刊名：European Journal of Medicinal Chemistry

出版年：2017

8.Histone deacetylase and acetyltransferase inhibitors modulate behavioral responses to social stress

作者：Katharine E. McCann ; ^{kmccann3@gsu.edu} ; Anna M. Rosenhauer ^{arosenhauer1@student.gsu.edu} ; Genna M.F. Jones ^{gjones26@student.gsu.edu} ; Alisa Norvelle ^{anorvelle@gsu.edu} ; Dennis C. Choi ^{dchoi15@gsu.edu} ; Kim L. Huhman ^{khuhman@gsu.edu}

关键词：Valproic acid ; Social defeat ; Epigenetics ; Medial prefrontal cortex

刊名：Psychoneuroendocrinology

出版年：2017

9.In vitro evaluation of penta-O-galloyl-β-d-glucose (PGG) on miRNA expression and apoptosis in BCR-ABL⁺ ALL

作者：N.S. Sanddhya^a ; ^{sanddhya_23@yahoo.com} ; R. Stalin^a ; P. Sachdanandam^a ; R. Malathi^b ; P. Shanthi^a ; ^{shanthipalanivelu@gmail.com}

关键词：HDACi ; histone deacetylase inhibitors ; ATCC ; the American Type Culture Condition ; PGG ; penta-O-galloyl-β-d-glucose ; ALL ; Acute Lymphoblastic Leukemia

刊名：Gene Reports

出版年：2017

10.Improving potency and metabolic stability by introducing an alkenyl linker to pyridine-based histone deacetylase inhibitors for orally available RUNX3 modulators

作者：Doona Song^a ; Chulho Lee^a ; Yoon Jeong Kook^a ; ^c ; Soo Jin Oh^b ; Jong Soon Kang^b ; Hyun-Jung Kim^a ; Gyoonhee Han^a ; ^c ; ^{gyoonhee@yonsei.ac.kr}

关键词：RUNX3 ; RUNX3 acetylation ; HDAC inhibition ; Epigenetic control ; Protein stabilization

刊名：European Journal of Medicinal Chemistry

出版年：2017

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