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SpringerLink电子期刊(2)
Elsevier电子期刊(21)
ACS电子期刊(5)
在“
Elsevier电子期刊
”中,
命中:
21
条,耗时:小于0.01 秒
在所有数据库中总计命中:
28
条
1.
Application of encoded library technology (ELT) to a protein-protein interaction target: Discovery of a potent class of integrin lymphocyte function-associated antigen
1
(
LFA
-
1
)
antagonists
作者:
Christopher S. Kollmann
a
;
Xiaopeng Bai
a
;
Ching-Hsuan Tsai
a
;
Hongfang Yang
a
;
Kenneth E. Lind
a
;
Steven R. Skinner
a
;
Zhengrong Zhu
a
;
David I. Israel
a
;
John W. Cuozzo
a
;
&dagger
;
;
Barry A. Morgan
a
;
Koichi Yuki
b
;
&Dagger
;
;
Can Xie
b
;
§
;
;
Timothy A. Springer
b
;
Motomu Shimaoka
b
;
¶
;
;
Ghotas Evindar
a
;
ghotas.x.evindar@gsk.com" class="auth_mail
关键词:
ELT
;
encoded library technology
;
LFA
-
1
;
lymphocyte function-associated antigen
1
;
ICAM-
1
;
intercellular adhesion molecule
1
;
PPI
;
protein&ndash
;
protein interactions
刊名:Bioorganic and Medicinal Chemistry
出版年:
1
April, 20
1
4
2.
Structure
1
3;activity relationship (SAR) of the ;
1
;-amino acid residue of potent tetrahydroisoquinoline (THIQ)-derived
LFA
-
1
/ICAM-
1
antagonists
作者:
Min Zhong
;
Emily J. Hanan
;
Wang Shen
;
Minna Bui
;
Michelle R. Arkin
;
Kenneth J. Barr
;
Marc J. Evanchik
;
Ute Hoch
;
Jennifer Hyde
;
Jose R. Martell
;
Johan D. Oslob
;
Kumar Paulvannan
;
Saileta Prabhu
;
Jeffr
关键词:
LFA
-
1
/ICAM-
1
antagonist
;
Tetrahydroisoquinoline
;
;
1
;
-Amino acid
;
Structure
1
3
;
activity relationship
;
(
S
)-2
;
3-Diaminopropanoic acid replacement
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:20
11
3.
S¨ªndrome del iris fl¨¢cido intraoperatorio
作者:
J. Gonzá
;
lez Martí
;
n-Moro
a
;
juliogmm@yahoo.es
;
F. Mu
1
;
oz Negrete
b
;
I. Lozano Escobar
a
;
Y. Ferná
;
ndez Miguel
a
关键词:
IFIS
;
Sí
;
ndrome del iris flá
;
cido intraoperatorio
;
Tamsulosina
;
Catarata
;
Receptor adrené
;
rgico a
lfa1
A
刊名:Archivos de la Sociedad Espa?ola de Oftalmolog¨ªa
出版年:20
1
3
4.
Chronic fluvoxamine treatment changes 5-HT
2A/2C
receptor-mediated behavior in o
lfa
ctory bulbectomized mice
作者:
Akira Oba
a
;
Osamu Nakagawasai
a
;
osamun@tohoku-pharm.ac.jp
;
Hiroshi Onogi
a
;
b
;
Wataru Nemoto
a
;
Fukie Yaoita
a
;
Yuichiro Arai
c
;
Koichi Tan-No
a
;
Takeshi Tadano
a
关键词:
O
lfa
ctory bulbectomy
;
Depression
;
5-HT2A receptor
;
5-HT2C receptor
;
Head twitch response
;
Fluvoxamine
刊名:Life Sciences
出版年:20
1
3
5.
Discovery of tetrahydroisoquinoline (THIQ) derivatives as potent and orally bioavailable
LFA
-
1
/ICAM-
1
antagonists
作者:
Min Zhong
;
Wang Shen
;
Kenneth J. Barr
;
Jennifer P. Arbitrario
;
Michelle R. Arkin
;
Minna Bui
;
Teresa Chen
;
Brian C. Cunningham
;
Marc J. Evanchik
;
Emily J. Hanan
;
Ute Hoch
;
Karen Huen
;
Jennifer Hyde
;
Je
关键词:
Leukocyte function-associated antigen-
1
(
LFA
-
1
)
;
Intercellular adhesion molecule-
1
(ICAM-
1
)
;
Tetrahydroisoquinoline (THIQ) derivative
;
Antagonist
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:20
1
0
6.
Design of
LFA
-
1
antagonists
based on a 2,3-dihydro-
1
H-pyrrolizin-5(7aH)-one scaffold
作者:
Dharmpal S. Dodd
;
Steven Sheriff
;
ChiehYing J. Chang
;
Dawn K. Stetsko
;
Linda M. Phillips
;
Yingru Zhang
;
Michele Launay
;
Dominique Potin
;
Wayne Vaccaro
;
Michael A. Poss
;
et al.
关键词:
LFA
-
1
antagonists
;
2
;
3-Dihydro-
1
H
-pyrrolizin-5-(7aH)-one
;
LFA
-
1
/ICAM interaction
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2007
7.
A new and practical boronic acid catalyzed intramolecular cyclodehydration of ureas for the synthesis of
LFA
-
1
antagonists
作者:
Rogelio P. Frutos
;
a
;
rfrutos@rdg.boehringer-ingelheim.com
;
Thomas Tampone
a
;
Jason A. Mulder
a
;
Yibo Xu
a
;
Diana Reeves
a
;
Xiao-Jun Wang
a
;
Li Zhang
a
;
Dhileepkumar Krishnamurthy
a
;
Chris H. Senanayake
a
刊名:Tetrahedron Letters
出版年:20
11
8.
The determination and correlation of molecular and cellular equilibrium K
d
and kinetic k
off
values for small molecule allosteric
antagonists
of
LFA
-
1
作者:
Gary O. Caviness
;
Mark E. Labadia
;
Patricia A. Giblin
;
Joseph R. Woska Jr.
;
Kathleen Last-Barney
;
Deborah D. Jeanfavre
;
Maurice M. Morelock
关键词:
SPR
;
Flow-cytometry
;
Receptor-occupancy
;
Allosteric
antagonists
;
Off-rates
;
Adhesion molecules
刊名:Biochemical Pharmacology
出版年:2007
9.
Integrin inside-out signaling and the immunological synapse
作者:
Timothy A Springer
1
;
springer_lab@idi.harvard.edu
;
Michael L Dustin
2
刊名:Current Opinion in Cell Biology
出版年:20
1
2
10.
Amino-substituted heterocycles as isosteres of trans-cinnamides: design and synthesis of heterocyclic biaryl sulfides as potent
antagonists
of
LFA
-
1
/ICAM-
1
binding
作者:
Wang
;
Gary T.
;
Wang
;
Sheldon
;
Gentles
;
Robert
;
Sowin
;
Thomas
;
Leitza
;
Sandra
;
Reilly
;
Edward B.
;
et. al.
关键词:
trans
-Cinnamide isostere
;
Cell adhesion
;
LFA
-
1
/ICAM-
1
binding
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2005
1
2
3
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