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Wiley电子期刊(7)	SpringerLink电子期刊(32)	Elsevier电子期刊(128)
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在“Elsevier电子期刊”中，命中：128条，耗时：0.0109678 秒

在所有数据库中总计命中：214条

1.Design, synthesis and structure-activity relationship of 4,5-dihydropyrrolo[3,4-c]pyrazol-6(1H)-ones as potent p53-MDM2 inhibitors

作者：Wei-Huang Zhou^a ; ^b ; Xi-Guo Xu^a ; ^b ; Jin Li^b ; Xiao Min^b ; Jian-Zhong Yao^b ; Guo-Qiang Dong^b ; Chun-Lin Zhuang^b ; ^{zclnathan@163.com} ; Zhen-Yuan Miao^b ; ^{miaozhenyuan@hotmail.com} ; Wan-Nian Zhang^a ; ^b ; ^{zhangwnk@hotmail.com}

关键词：p53-MDM2 ; Protein&ndash ; protein interaction ; Inhibitors ; Drug design ; Structure&ndash ; activity relationships ; Antiproliferative

刊名：Chinese Chemical Letters

出版年：2017

2.Rational design and synthesis of 1,5-disubstituted tetrazoles as potent inhibitors of the MDM2-p53 interaction

作者：Ewa Surmiak^a ; Constantinos G. Neochoritis^b ; Bogdan Musielak^a ; Aleksandra Twarda-Clapa^c ; ^d ; Katarzyna Kurpiewska^a ; Grzegorz Dubin^c ; ^d ; Carlos Camacho^e ; Tad A. Holak^a ; ^d ; Alexander Dö ; mling^b ; ^{a.s.s.domling@rug.nl}

刊名：European Journal of Medicinal Chemistry

出版年：2017

3.Synthesis and biological evaluation of thiazole derivatives as novel USP7 inhibitors

作者：Chao Chen^a ; ^b ; ¹ ; Jiemei Song^a ; ^b ; ¹ ; Jinzheng Wang^a ; ^b ; ¹ ; Chang Xu^a ; ^b ; Caiping Chen^a ; ^b ; Wei Gu^c ; Hongbin Sun^a ; ^b ; ^{hongbinsun@cpu.edu.cn} ; Xiaoan Wen^a ; ^b ; ^{wxagj@126.com}

关键词：USP7 inhibitor ; Thiazole derivatives ; Human colon cancer

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

4.Roles of TP53 in determining therapeutic sensitivity, growth, cellular senescence, invasion and metastasis

作者：James A. McCubrey^a ; ^{mccubreyj@ecu.edu} ; Kvin Lertpiriyapong^b ; Timothy L. Fitzgerald^c ; Alberto M. Martelli^d ; Lucio Cocco^d ; Dariusz Rakus^e ; Agnieszka Gizak^e ; Massimo Libra^f ; Melchiorre Cervello^g ; Guiseppe Montalto^h ; Li V. Yangⁱ ; Stephen L. Abrams^a ; Linda S. Steelman^a

关键词：TP53 ; miRs ; MDM2 ; Nutlin-3 chemosensitivity ; Cellular senescence ; Invasion ; Metastasis

刊名：Advances in Biological Regulation

出版年：2017

5.Proteasome inhibitors in cancer therapy: Treatment regimen and peripheral neuropathy as a side effect

作者：Gulce Sari Kaplan^a ; Ceyda Corek Torcun^a ; Tilman Grune^b ; Nesrin Kartal Ozer^a ; Betul Karademir^a ; ^{betulkarademir@marmara.edu.tr}

关键词：AIF ; apoptosis inducing factor ; Ang ; angiopoietin ; AP-1 ; activator protein-1 ; APEX ; Assessment of Proteasome Inhibition for Extending Remissions ; ATP ; adenosine-5&prime ; -triphosphate ; BiPN ; bortezomib-induced peripheral neuropathy ; CiPN ; chemotherapy-induced peripheral neuropathy ; CREST ; Clinical Response and Efficacy Study of Bortezomib in the Treatment of Relapsing Multiple Myeloma ; DRG ; dorsal root ganglia ; FDA ; food and drug administration ; IL ; interleukin ; MDM2 ; mouse double minute 2 ; MDR1

刊名：Free Radical Biology and Medicine

出版年：2017

6.A triple exon-skipping luciferase reporter assay identifies a new CLK inhibitor pharmacophore

作者：Yihui Shi ; Jaehyeon Park ; Chandraiah Lagisetti ; Wei Zhou ; Lidia C. Sambucetti ; Thomas R. Webb ; ^{thomas.webb@sri.com}

关键词：CLK ; cdc2-like kinase ; MDM2 ; mouse double minute 2 homolog ; Luc ; luciferase ; TEA ; triethylamine ; DIPEA ; diisopropylethylamine ; EtOAc ; ethyl acetate

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

7.Discovery of a novel class of highly potent inhibitors of the p53-MDM2 interaction by structure-based design starting from a conformational argument

作者：Pascal Furet ; ^{pascal.furet@novartis.com" class="auth_mail" title="E-mail the corresponding author} ; Keiichi Masuya ; Joerg Kallen ; Thé ; rè ; se Stachyra-Valat ; Stephan Ruetz ; Vito Guagnano ; Philipp Holzer ; Robert Mah ; Stefan Stutz ; Andrea Vaupel ; Patrick Chè ; ne ; Sé ; bastien Jeay ; Achim Schlapbach

关键词：p53&ndash ; MDM2 inhibitors ; Protein&ndash ; protein interaction inhibitors ; Anticancer agents ; Structure-based design

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

8.An Efficient Protein System for Screening Specific MdmX and Mdm2 Inhibitors

刊名：Biophysical Journal

出版年：2017

9.Discovery of novel dual inhibitors against Mdm2 and Mdmx proteins by in silico approaches and binding assay

作者：Sahand Golestanian^a ; ¹ ; Amirhossein Sharifi^a ; ¹ ; Grzegorz M. Popowicz^b ; Homa Azizian^c ; Alireza Foroumadi^a ; Aleksandra Szwagierczak^b ; Tad A. Holak^b ; ^{holak@biochem.mpg.de" class="auth_mail" title="E-mail the corresponding author} ; Massoud Amanlou^a ; ^{amanlou@tums.ac.ir" class="auth_mail" title="E-mail the corresponding author}

关键词：Dual inhibitors ; Mdm2 & Mdmx ; Drug design ; p53 ; In silico process ; Qualitative SAR

刊名：Life Sciences

出版年：2016

10.Discovery of Dual Inhibitors of MDM2 and XIAP for Cancer Treatment

作者：Lubing Gu¹ ; ⁴ ; Hailong Zhang¹ ; ⁴ ; Tao Liu¹ ; ⁴ ; Sheng Zhou³ ; ⁴ ; Yuhong Du² ; Jing Xiong³ ; Sha Yi¹ ; Cheng-Kui Qu¹ ; Haian Fu² ; Muxiang Zhou¹ ; ⁵ ; ^{mzhou@emory.edu" class="auth_mail" title="E-mail the corresponding author}

刊名：Cancer Cell

出版年：2016

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