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Elsevier电子期刊(14)
ACS电子期刊(4)
在“
Elsevier电子期刊
”中,
命中:
14
条,耗时:小于0.01 秒
在所有数据库中总计命中:
18
条
1.
Highly potent and selective cannabinoid receptor 2 agonists: Initial hit optimization of an adamantyl hit series identified from high-through-put screening
作者:
Matthias
Nettekoven
a
;
matthias
.
nettekoven
@roche.com
;
Jü
;
rgen Fingerle
b
;
Uwe Grether
a
;
Sabine Grü
;
ner
b
;
Atsushi Kimbara
a
;
Bernd Pü
;
llmann
a
;
Mark Rogers-Evans
a
;
Stephan Rö
;
ver
a
;
Franz Schuler
c
;
Tanja Schulz-Gasch
a
;
Christoph Ullmer
b
关键词:
Cannabinoid receptor
;
Adamantane
;
¦Â-Arrestin
;
Hit optimization
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2013
2.
Evaluation of a flow-photochemistry platform for the synthesis of compact modules
作者:
Matthias
Nettekoven
;
matthias
.
nettekoven
@roche.com
;
Bernd Pü
;
llmann
;
Rainer E. Martin
;
David Wechsler
关键词:
Flow-chemistry
;
Photochemistry
;
Modules
;
Bicyclo[3.2.0]heptane
刊名:Tetrahedron Letters
出版年:2012
3.
Diastereoselective synthesis of an argatroban intermediate, ethyl (2R,4R)-4-methylpipecolate, by means of a Mandyphos/rhodium complex-catalyzed hydrogenation
作者:
Patrizia Ferraboschi
a
;
;
patrizia.ferraboschi@unimi.it
;
Maria De Mieri
a
;
Paride Grisenti
b
;
Matthias
Lotz
c
;
Ulrike
Nettekoven
c
刊名:Tetrahedron: Asymmetry
出版年:2011
4.
Rational design of novel pyrrolidine derivatives as orally active neurokinin-3 receptor antagonists
作者:
Hassen Ratni
;
Theresa M. Ballard
;
Caterina Bissantz
;
Torsten Hoffmann
;
Philippe Jablonski
;
Frederic Knoflach
;
Henner Knust
;
Parichehr Malherbe
;
Matthias
Nettekoven
;
Angelique Patiny-Adam
;
Claus Riemer
关键词:
NK3
;
Pyrrolidine
;
Antipsychotic
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2010
5.
Selective naphthalene H
3
receptor inverse agonists with reduced potential to induce phospholipidosis and their quinoline analogs
作者:
Rosa Marí
;
a Rodrí
;
guez Sarmiento
;
Matthias
H.
Nettekoven
;
Sven Taylor
;
Jean-Marc Plancher
;
Hans Richter
;
Olivier Roche
关键词:
Histamine H
3
receptor
;
SAR
;
Pharmacophore model
;
Naphthalene
;
Phospholipidosis
;
Amphiphilic vector
;
Amphiphilicity
;
Quinoline
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2009
6.
Discovery of benzoylpiperazines as a novel class of potent and selective GlyT1 inhibitors
作者:
Emmanuel Pinard
;
Daniela Alberati
;
Edilio Borroni
;
Holger Fischer
;
Dominik Hainzl
;
Synè
;
se Jolidon
;
Jean-Luc Moreau
;
Robert Narquizian
;
Matthias
Nettekoven
;
Roger D. Norcross
;
Henri Stalder
;
Andre
关键词:
GlyT1
;
Glycine
;
Transporter
;
Inhibitor
;
Schizophrenia
;
NMDA
;
Benzoylpiperazine
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2008
7.
Refinement of histamine H3 ligands pharmacophore model leads to a new class of potent and selective naphthalene inverse agonists
作者:
Olivier Roche
;
Matthias
Nettekoven
;
Walter Vifian
;
Rosa Maria Rodriguez Sarmiento
关键词:
Histamine H
3
receptor
;
SAR
;
Pharmacophore model
;
Naphthalene
;
GPCR
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2008
8.
Isomeric thiazole derivatives as ligands for the neuropeptide Y5 receptor
作者:
Nettekoven
;
Matthias
;
Guba
;
Wolfgang
;
Neidhart
;
Werner
;
Mattei
;
Patrizio
;
Pflieger
;
Philippe
;
et. al.
关键词:
Conformational analysis
;
Neuropeptide Y5
;
Iterative parallel solution-phase chemistry
;
SAR
;
Thiazoles
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2005
9.
Novel and potent NPY5 receptor antagonists derived from virtual screening and iterative parallel chemistry design
作者:
Guba
;
Wolfgang
;
Neidhart
;
Werner
;
Nettekoven
;
Matthias
关键词:
Pharmacophores
;
Virtual screening
;
Parallel chemistry
;
Lead generation
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2005
10.
Comparison of inhibitory activity of isomeric triazolopyridine derivatives towards adenosine receptor subtypes or do similar structures reveal similar bioactivities?
作者:
Guba
;
Wolfgang
;
Nettekoven
;
Matthias
;
Pü
;
llmann
;
Bernd
;
Riemer
;
Claus
;
Schmitt
;
Sé
;
bastien
关键词:
Adenosine
;
Amination
;
Combinatorial chemistry
;
H-bond donor/acceptor strength triazolopyridine derivatives
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2004
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