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在“
Elsevier电子期刊
”中,
命中:
3,583
条,耗时:小于0.01 秒
在所有数据库中总计命中:
5,500
条
1.
PARP
-
1
Controls the Adipogenic Transcriptional Program by PARylating C/EBPβ and Modulating Its Transcriptional Activity
作者:
Xin Luo
1
;
2
;
3
;
8
;
Keun Woo Ryu
1
;
2
;
3
;
8
;
Dae-Seok Kim
1
;
2
;
Tulip Nandu
1
;
2
;
Carlos J. Medina
4
;
Rebecca Gupte
1
;
2
;
Bryan A. Gibson
1
;
2
;
5
;
Raymond E. Soccio
4
;
Yonghao Yu
6
;
Rana K. Gupta
7
;
W. Lee Kraus
1
;
2
;
3
;
9
;
lee.kraus@utsouthwestern.edu
关键词:
adipogenesis
;
C/EBPβ
;
DNA binding
;
gene expression
;
PARP
inhibitor
;
PARP
-
1
;
PARylation
;
poly(ADP-ribose)
;
transcription
刊名:Molecular Cell
出版年:20
1
7
2.
Associations of
PARP
-
1
variant rs
11
364
1
0 with PARP activities, oxidative DNA damage, and the risk of age-related cataract in a Chinese Han population: A two-stage case-control analysis
作者:
Ning-hua Cui
a
;
nhcui20
1
6@
1
63.com
;
Chen Qiao
b
;
Xiao-ke Chang
c
;
Li Wei
d
关键词:
PARP
-
1
;
poly (ADP-ribose) polymerase-
1
;
ARC
;
age-related cataract
;
8-OHdg
;
8-hydroxy-2&prime
;
-deoxyguanosine
;
HRM
;
high-resolution melting
;
PBMCs
;
peripheral blood mononuclear cells
;
PSC
;
posterior subcapsular
;
LECs
;
lens epithelial cells
;
BER
;
base excision repair
;
SNP
;
single nucleotide polymorphism
;
LOCSIII
;
Lens Opacities Classification System III
;
FPG
;
fasting glucose levels
刊名:Gene
出版年:20
1
7
3.
Design, synthesis and biological activity of novel molecules designed to target
PARP
and DNA
作者:
Elliot Goodfellow
a
;
Zhor Senhaji Mouhri
a
;
Christopher Williams
b
;
Bertrand J. Jean-Claude
a
;
bertrandj.jean-claude@mcgill.ca
关键词:
PARP
inhibitors
;
BRCA mutation
;
Synthetic lethality
;
DNA damage
;
Bis-targeting
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:20
1
7
4.
Combination strategy of
PARP
inhibitor with antioxidant prevent bioenergetic deficits and inflammatory changes in CCI-induced neuropathy
作者:
Prashanth Komirishetty
a
;
d
;
Aparna Areti
a
;
Ranadeep Gogoi
b
;
Ramakrishna Sistla
c
;
Ashutosh Kumar
a
;
ashutosh.niperhyd@gov.in
;
ashutoshniper@gmail.com
关键词:
Chronic constriction injury
;
Quercetin
;
4-ANI
;
PARP
;
Oxidative stress
;
Bioenergetic crisis
刊名:Neuropharmacology
出版年:20
1
7
5.
MiR-335 regulates the chemo-radioresistance of small cell lung cancer cells by targeting
PARP
-
1
作者:
Yingshan Luo
a
;
Lihua Tong
a
;
Hui Meng
a
;
Weiliang Zhu
a
;
Linlang Guo
b
;
Ting Wei
a
;
258077534@qq.com
;
Jian Zhang
a
;
blacktiger@
1
39.com
关键词:
SCLC
;
small cell lung cancer
;
PARP
-
1
;
Poly [ADP-ribose] polymerase
1
;
miRNAs
;
microRNAs
;
ccRcc
;
clear cell renal cell carcinoma
;
NAD
+ ;
;
nicotinamide adenine dinucleotide
;
qRT-PCR
;
quantitative real-time PCR
;
GAPDH
;
glyceraldehyde-3-phosphate dehydrogenase
;
DDP
;
cisplatin
;
VP-
1
6
;
etoposide
;
ADM
;
Adriamycin
;
CCK-8
;
Cell Counting Kit-8
;
IC50
;
the half maximal inhibitory concentration of a substance
刊名:Gene
出版年:20
1
7
6.
MLN4924 suppresses the BRCA
1
complex and synergizes with
PARP
inhibition in NSCLC cells
作者:
Zong-Pei Guo
a
;
1
;
Ying-Chun Hu
a
;
1
;
Yu Xie
b
;
Feng Jin
c
;
Zhi-Quan Song
a
;
Xiao-Dan Liu
a
;
Teng Ma
a
;
mateng829
1
3@
1
63.com
;
Ping-Kun Zhou
a
;
b
;
zhoupk@bmi.ac.cn
关键词:
Neddylation
;
BRCA
1
;
PARP1
;
NSCLC
;
Double strand break
刊名:Biochemical and Biophysical Research Communications
出版年:20
1
7
7.
Poly(ADP-ribose)polymerase (
PARP
) inhibition and anticancer activity of simmiparib, a new inhibitor undergoing clinical trials
作者:
Bo Yuan
a
;
b
;
1
;
Na Ye
b
;
c
;
1
;
Shan-Shan Song
a
;
b
;
Yu-Ting Wang
a
;
b
;
Zilan Song
b
;
c
;
Hua-Dong Chen
a
;
b
;
Chuan-Huizi Chen
a
;
b
;
Xia-Juan Huan
a
;
b
;
Ying-Qing Wang
a
;
b
;
Yi Su
a
;
b
;
Yan-Yan Shen
a
;
b
;
Yi-Ming Sun
a
;
b
;
Xin-Ying Yang
a
;
b
;
Yi Chen
a
;
b
;
Shi-Yan Guo
d
;
Yong Gan
d
;
Zhi-Wei Gao
d
;
Xiao-Yan Chen
d
;
Jian Ding
a
;
b
;
Jin-Xue He
a
;
b
;
jxhe@simm.ac.cn
;
Ao Zhang
b
;
c
;
aozhang@simm.ac.cn
;
Ze-Hong Miao
a
;
b
;
zhmiao@simm.ac.cn
关键词:
Homologous recombination repair defects
;
Olaparib
;
Growth inhibition
;
Patient-derived xenografts
;
Pharmacokinetics
刊名:Cancer Letters
出版年:20
1
7
8.
Inhibiting poly ADP-ribosylation increases fatty acid oxidation and protects against fatty liver disease
作者:
Karim Gariani
1
;
Dongryeol Ryu
1
;
&dagger
;
;
Keir J. Menzies
1
;
3
;
&dagger
;
;
Hyon-Seung Yi
5
;
Sokrates Stein
2
;
4
;
Hongbo Zhang
1
;
Alessia Perino
2
;
Vera Lemos
2
;
Elena Katsyuba
1
;
Pooja Jha
1
;
Sandrine Vijgen
7
;
Laura Rubbia-Brandt
7
;
Yong Kyung Kim
5
;
Jung Tae Kim
6
;
Koon Soon Kim
5
;
Minho Shong
5
;
Kristina Schoonjans
2
;
Johan Auwerx
1
;
admin.auwerx@epfl.ch
关键词:
Non-alcoholic fatty liver disease
;
Poly ADP-ribosylation
;
Sirtuin
;
PARP
inhibitor
;
PARylation
;
NAD
刊名:Journal of Hepatology
出版年:20
1
7
9.
DNA Repair in Prostate Cancer: Biology and Clinical Implications
作者:
Joaquin Mateo
a
;
b
;
Gunther Boysen
a
;
Christopher E. Barbieri
c
;
d
;
e
;
Helen E. Bryant
f
;
Elena Castro
g
;
Pete S. Nelson
h
;
i
;
David Olmos
g
;
j
;
Colin C. Pritchard
h
;
Mark A. Rubin
d
;
e
;
k
;
Johann S. de Bono
a
;
b
;
johann.de-bono@icr.ac.uk
关键词:
Prostate cancer
;
DNA repair
;
PARP
;
BRCA
;
Personalized medicine
;
DNA damage
刊名:European Urology
出版年:20
1
7
10.
Iodinated benzimidazole
PARP
radiotracer for evaluating PARP
1
/2 expression in vitro and in vivo
作者:
Redmond-Craig Anderson
;
Mehran Makvandi
;
Kuiying Xu
;
Brian P. Lieberman
;
Chenbo Zeng
;
Daniel A. Pryma
;
Robert H. Mach
;
rmach@mail.med.upenn.edu" class="auth_mail" title="E-mail the corresponding author
关键词:
PARP
-inhibitor
;
BRCA
1
/2
;
Cancer imaging
;
PARP
-2
刊名:Nuclear Medicine and Biology
出版年:20
1
6
1
2
3
4
5
6
7
8
9
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