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Wiley电子期刊(13)	SpringerLink电子期刊(448)	Elsevier电子期刊(1040)
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在“Elsevier电子期刊”中，命中：1,040条，耗时：0.0169911 秒

在所有数据库中总计命中：1,559条

1.PARP-1 Controls the Adipogenic Transcriptional Program by PARylating C/EBPβ and Modulating Its Transcriptional Activity

作者：Xin Luo¹ ; ² ; ³ ; ⁸ ; Keun Woo Ryu¹ ; ² ; ³ ; ⁸ ; Dae-Seok Kim¹ ; ² ; Tulip Nandu¹ ; ² ; Carlos J. Medina⁴ ; Rebecca Gupte¹ ; ² ; Bryan A. Gibson¹ ; ² ; ⁵ ; Raymond E. Soccio⁴ ; Yonghao Yu⁶ ; Rana K. Gupta⁷ ; W. Lee Kraus¹ ; ² ; ³ ; ⁹ ; ^{lee.kraus@utsouthwestern.edu}

关键词：adipogenesis ; C/EBPβ ; DNA binding ; gene expression ; PARP inhibitor ; PARP-1 ; PARylation ; poly(ADP-ribose) ; transcription

刊名：Molecular Cell

出版年：2017

2.Combination strategy of PARP inhibitor with antioxidant prevent bioenergetic deficits and inflammatory changes in CCI-induced neuropathy

作者：Prashanth Komirishetty^a ; ^d ; Aparna Areti^a ; Ranadeep Gogoi^b ; Ramakrishna Sistla^c ; Ashutosh Kumar^a ; ^{ashutosh.niperhyd@gov.in} ; ^{ashutoshniper@gmail.com}

关键词：Chronic constriction injury ; Quercetin ; 4-ANI ; PARP ; Oxidative stress ; Bioenergetic crisis

刊名：Neuropharmacology

出版年：2017

3.Inhibiting poly ADP-ribosylation increases fatty acid oxidation and protects against fatty liver disease

作者：Karim Gariani¹ ; Dongryeol Ryu¹ ; ^&dagger ; ; Keir J. Menzies¹ ; ³ ; ^&dagger ; ; Hyon-Seung Yi⁵ ; Sokrates Stein² ; ⁴ ; Hongbo Zhang¹ ; Alessia Perino² ; Vera Lemos² ; Elena Katsyuba¹ ; Pooja Jha¹ ; Sandrine Vijgen⁷ ; Laura Rubbia-Brandt⁷ ; Yong Kyung Kim⁵ ; Jung Tae Kim⁶ ; Koon Soon Kim⁵ ; Minho Shong⁵ ; Kristina Schoonjans² ; Johan Auwerx¹ ; ^{admin.auwerx@epfl.ch}

关键词：Non-alcoholic fatty liver disease ; Poly ADP-ribosylation ; Sirtuin ; PARP inhibitor ; PARylation ; NAD

刊名：Journal of Hepatology

出版年：2017

4.Poly(ADP-ribose)polymerase (PARP) inhibition and anticancer activity of simmiparib, a new inhibitor undergoing clinical trials

作者：Bo Yuan^a ; ^b ; ¹ ; Na Ye^b ; ^c ; ¹ ; Shan-Shan Song^a ; ^b ; Yu-Ting Wang^a ; ^b ; Zilan Song^b ; ^c ; Hua-Dong Chen^a ; ^b ; Chuan-Huizi Chen^a ; ^b ; Xia-Juan Huan^a ; ^b ; Ying-Qing Wang^a ; ^b ; Yi Su^a ; ^b ; Yan-Yan Shen^a ; ^b ; Yi-Ming Sun^a ; ^b ; Xin-Ying Yang^a ; ^b ; Yi Chen^a ; ^b ; Shi-Yan Guo^d ; Yong Gan^d ; Zhi-Wei Gao^d ; Xiao-Yan Chen^d ; Jian Ding^a ; ^b ; Jin-Xue He^a ; ^b ; ^{jxhe@simm.ac.cn} ; Ao Zhang^b ; ^c ; ^{aozhang@simm.ac.cn} ; Ze-Hong Miao^a ; ^b ; ^{zhmiao@simm.ac.cn}

关键词：Homologous recombination repair defects ; Olaparib ; Growth inhibition ; Patient-derived xenografts ; Pharmacokinetics

刊名：Cancer Letters

出版年：2017

5.Poly (ADP-ribose) polymerase inhibitors selectively induce cytotoxicity in TCF3-HLF-positive leukemic cells

作者：Jinhua Piao^a ; Shiori Takai^a ; Takahiro Kamiya^b ; Takeshi Inukai^c ; Kanji Sugita^c ; Kazuma Ohyashiki^d ; Domenico Delia^e ; Mitsuko Masutani^f ; Shuki Mizutani^a ; ^{skkmiz@gmail.com} ; Masatoshi Takagi^a ; ^{m.takagi.ped@tmd.ac.jp}

关键词：Acute lymphoblastic leukemia ; TCF3-HLF ; Homologous recombination repair ; PARP inhibitor

刊名：Cancer Letters

出版年：2017

6.MLN4924 suppresses the BRCA1 complex and synergizes with PARP inhibition in NSCLC cells

作者：Zong-Pei Guo^a ; ¹ ; Ying-Chun Hu^a ; ¹ ; Yu Xie^b ; Feng Jin^c ; Zhi-Quan Song^a ; Xiao-Dan Liu^a ; Teng Ma^a ; ^{mateng82913@163.com} ; Ping-Kun Zhou^a ; ^b ; ^{zhoupk@bmi.ac.cn}

关键词：Neddylation ; BRCA1 ; PARP1 ; NSCLC ; Double strand break

刊名：Biochemical and Biophysical Research Communications

出版年：2017

7.Shikonin inhibits gefitinib-resistant non-small cell lung cancer by inhibiting TrxR and activating the EGFR proteasomal degradation pathway

作者：Xia Li¹ ; Xing-Xing Fan¹ ; Ze-Bo Jiang ; Wings TY Loo ; Xiao-Jun Yao ; Elaine Lai-Han Leung ; ^{lhleung@must.edu.mo} ; Louis WC Chow ; ^{wcchow@must.edu.mo} ; Liang Liu ; ^{lliu@must.edu.mo}

关键词：NSCLC ; non-small cell lung cancer cell ; ROS ; reactive oxygen species ; EGFR ; epidermal growth factor receptor ; T790M ; a substitution mutation of threonine with methionine at position 790 of EGFR ; TrxR ; thioredoxin reductases ; MTT ; 3-(4 ; 5-dimetrylthiazol)-2 ; 5-diphenyltetrazolium bromide ; DCFDA ; dichlorofluorescein diacetate ; PBS ; phosphate-buffered saline ; RIPA ; radioimmunoprecipitation assay ; PARP ; poly (ADP-ribosyl) polymerase ; NAC ; N-acetyl-l-cysteine ; MG132 ; proteasomal degradation pathway inh

刊名：Pharmacological Research

出版年：2017

8.CRISPR-mediated targeting of HER2 inhibits cell proliferation through a dominant negative mutation

作者：Huajing Wang ; William Sun ; ^{wsun@ibn.a-star.edu.sg}

关键词：Cas9 ; ERBB2 ; Breast cancer ; PARP inhibitor ; Trastuzumab ; Therapeutic

刊名：Cancer Letters

出版年：2017

9.Inhibition of heat shock protein (Hsp) 90 potentiates the antiproliferative and pro-apoptotic effects of 2-(4′fluoro-phenylamino)-4H-1,3-thiazine[6,5-b]indole in A2780cis cells

作者：Zuzana Solá ; rová ; ^a ; Martin Kello^a ; Lenka Varinská ; ^a ; Mariana Budovská ; ^b ; Peter Solá ; r^c ; ^{peter.solar@upjs.sk}

关键词：thiazine[6 ; 5-b]indole ; 2-(4&prime ; fluoro-phenylamino)-4H-1 ; 3-thiazine[6 ; 5-b]indole ; Hsp ; heat shock protein ; 17-DMAG ; 17-dimethylaminoethylamino-17-demethoxygeldanamycin ; 17-AAG ; 17-(allylamino)-17-demethoxygeldanamycin ; A2780 ; human ovarian adenocarcinoma cell line ; A2780cis ; human ovarian adenocarcinoma cell line resistant to cisplatin ; PARP ; poly (ADP-ribose) polymerase ; MMP ; mitochondrial membrane potential ; An ; annexin ; PI ; propidium iodide

刊名：Biomedicine & Pharmacotherapy

出版年：2017

10.CDK12 Inhibition Reverses De Novo and Acquired PARP Inhibitor Resistance in BRCA Wild-Type and Mutated Models of Triple-Negative Breast Cancer

作者：Shawn F. Johnson¹ ; Cristina Cruz² ; ³ ; Ann Katrin Greifenberg⁴ ; ⁵ ; Sofia Dust⁴ ; ⁵ ; Daniel G. Stover¹ ; ⁶ ; ⁷ ; David Chi¹ ; Benjamin Primack⁸ ; ⁹ ; Shiliang Cao¹ ; Andrea J. Bernhardy¹⁰ ; Rhiannon Coulson¹¹ ; Jean-Bernard Lazaro⁸ ; Bose Kochupurakkal⁸ ; Heather Sun¹² ; Christine Unitt¹² ; Lisa A. Moreau⁸ ; ⁹ ; Kristopher A. Sarosiek¹ ; Maurizio Scaltriti¹³ ; Dejan Juric¹⁴ ; ¹⁵ ; José ; Baselga¹³ ; Andrea L. Richardson¹² ; ¹⁶ ; Scott J. Rodig¹² ; Alan D. D&rsquo ; Andrea⁸ ; ⁹ ; Judith Balmañ ; a³ ; Neil Johnson¹⁰ ; Matthias Geyer⁴ ; ⁵ ; Violeta Serra² ; Elgene Lim¹ ; ¹¹ ; ^{e.lim@garvan.org.au} ; Geoffrey I. Shapiro¹ ; ⁷ ; ¹⁷ ; ^{geoffrey_shapiro@dfci.harvard.edu}

关键词：dinaciclib ; CDK inhibitor ; CDK12 ; homologous recombination repair ; PARP inhibitor ; triple-negative breast cancer ; BRCA-associated breast cancer

刊名：Cell Reports

出版年：2016

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