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Wiley电子期刊(9)
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Elsevier电子期刊(330)
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NATURE电子期刊(6)
ACS电子期刊(26)
在“
Elsevier电子期刊
”中,
命中:
330
条,耗时:小于0.01 秒
在所有数据库中总计命中:
465
条
1.
Inhibitory potential of flavonoids on PtdIns(3,4,5)P3 binding with the phosphoinositide-dependent kinase 1 pleckstrin homology domain
作者:
Yelin Kang
a
;
1
;
Bong-Gyu Kim
b
;
1
;
Sunghoon Kim
a
;
Youngshim Lee
c
;
Youngdae Yoon
a
;
yyoon21@gmail.com
关键词:
PtdIns(3
4 ;
5)P3
;
Pleckstrin homology (PH) domain
;
PDK1
;
Flavonoid
;
QSAR
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2017
2.
Single Molecule Studies of a Membrane-Bound, Master Kinase Circuit... Detecting Interactions of Two Master Kinase Pairs on the Membrane,
PDK1
-AKT1 and PDK1-PKC Alpha
刊名:Biophysical Journal
出版年:2017
3.
Hippocalcin Promotes Neuronal Differentiation and Inhibits Astrocytic Differentiation in Neural Stem Cells
作者:
Shin-Young Park
1
;
Sung Nyo Yoon
1
;
Min-Jeong Kang
1
;
YunYoung Lee
1
;
Sung Jun Jung
2
;
Joong-Soo Han
1
;
jshan@hanyang.ac.kr
关键词:
hippocalcin (HPCA)
;
neural stem cells
;
neurogenesis
;
gliogenesis
;
phospholipase D1 (PLD1)
;
signal transducers and activator of transcription 3 (STAT3)
;
phosphoinositide-dependent protein kinase-1 (
PDK1
)
;
SH2-domain-containing tyrosine phosphatase-1 (SHP-1)
刊名:Stem Cell Reports
出版年:2017
4.
Claudin-5, -7, and -18 suppress proliferation mediated by inhibition of phosphorylation of Akt in human lung squamous cell carcinoma
作者:
Risa Akizuki
;
Shun Shimobaba
;
Toshiyuki Matsunaga
;
Satoshi Endo
;
Akira Ikari
;
ikari@gifu-pu.ac.jp
关键词:
CLDNs
;
claudins
;
CA
;
constitutively active
;
DAPI
;
4&prime
;
6-diamidino-2-phenylindole
;
DN
;
dominant negative
;
EGFR
;
epidermal growth factor receptor
;
ERK
;
extracellular signal-regulated kinase
;
LDH
;
lactate dehydrogenase
;
MAP
;
mitogen-activated protein
;
NSCLC
;
non-small cell lung cancer
;
PCR
;
polymerase chain reaction
;
PDK1
;
3-phosphoinositide-dependent protein kinase-1
;
PI
;
propidium iodide
;
PI3K
;
phosphatidylinositol-3 kinase
;
PKA
;
protein kinase A
;
SCLC
;
small cell lung cancer
;
SDS-PAGE
;
sodi
刊名:Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
出版年:2017
5.
PDK1
in NF-κB signaling is a target of Xanthium strumarium methanolic extract-mediated anti-inflammatory activities
作者:
Muhammad Jahangir Hossen
a
;
b
;
1
;
Jae Youl Cho
a
;
1
;
Daewon Kim
c
;
dr_dwkim@dankook.ac.kr" class="auth_mail" title="E-mail the corresponding author
关键词:
Xs-ME
;
methanolic extract of Xanthium strumarium
;
HPLC
;
high performance liquid chromatography
;
PGE2
;
prostaglandin E2
;
NO
;
nitric oxide
;
COX
;
cyclooxygenase
;
iNOS
;
inducible NO synthase
;
TLR
;
Toll-like receptor (TLR)
;
NF-κB
;
nuclear factor-κB
;
Akt
;
protein kinase B
;
IKK
;
IκBα kinase
;
MyD88
;
myeloid differentiation primary response protein-88
;
PDK1
;
3-phosphoinositide-dependent kinase 1
;
EIA
;
enzyme immunoassay
;
MTT
;
(3&ndash
4 ;
5-dimethylthiazol-2-yl)-2
;
5-diphenyltetrazolium bromide
;
LPS
;
lipopo
刊名:Journal of Ethnopharmacology
出版年:2016
6.
Lipid regulators of Pkh2 in Candida albicans, the protein kinase ortholog of mammalian
PDK1
作者:
Daniel Pastor-Flores
a
;
Jö
;
rg O. Schulze
a
;
Anna Bahí
;
b
;
c
;
Evelyn Sü
;
ß
;
a
;
Antonio Casamayor
b
;
c
;
antonio.casamayor@uab.es" class="auth_mail" title="E-mail the corresponding author
;
Ricardo M. Biondi
a
;
biondi@med.uni-frankfurt.de" class="auth_mail" title="E-mail the corresponding author
关键词:
Budding yeast
;
C. albicans
;
Pkh
;
PDK1
;
Cell wall integrity
;
Allostery
;
Sphingosine
;
PHS
;
DHS
;
PI(3
;
4)P2
;
PI(4
;
5)P2
;
PI(3
4 ;
5)P3
;
PIP3
;
Sulfatide
;
Phosphatidic acid
;
Phosphatidylserine
;
Phosphatidylethanolamine
;
Phosphatidylcholine
刊名:Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids
出版年:2016
7.
Discovery of novel 7-azaindoles as
PDK1
inhibitors
作者:
Margarita Wucherer-Plietker
a
;
Eugen Merkul
b
;
&dagger
;
;
Thomas J.J. Mü
;
ller
b
;
&dagger
;
;
Christina Esdar
a
;
Thorsten Knö
;
chel
a
;
Timo Heinrich
a
;
Hans-Peter Buchstaller
a
;
Hartmut Greiner
a
;
Dieter Dorsch
a
;
Dirk Finsinger
a
;
Michel Calderini
a
;
David Bruge
a
;
Ulrich Grä
;
dler
a
;
ulrich.graedler@merckgroup.com" class="auth_mail" title="E-mail the corresponding author
关键词:
PDK1
;
Kinase inhibitor
;
Structure-based design
;
Fragment-screening
;
Protein crystallography
;
Virtual screening
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2016
8.
Claudin-18 inhibits cell proliferation and motility mediated by inhibition of phosphorylation of
PDK1
and Akt in human lung adenocarcinoma A549 cells
作者:
Shun Shimobaba
a
;
Saeko Taga
a
;
Risa Akizuki
a
;
Asami Hichino
a
;
Satoshi Endo
a
;
Toshiyuki Matsunaga
a
;
Ryo Watanabe
b
;
Masahiko Yamaguchi
b
;
Yasuhiro Yamazaki
b
;
Junko Sugatani
b
;
Akira Ikari
a
;
ikari@gifu-pu.ac.jp" class="auth_mail" title="E-mail the corresponding author
关键词:
DAPI
;
4&prime
;
6-diamidino-2-phenylindole
;
EGFR
;
epidermal growth factor receptor
;
HEMA
;
poly-2-hydroxyethyl methacrylate
;
KO
;
knockout
;
MAP
;
mitogen-activated protein
;
MMP
;
matrix metalloproteinase
;
NSCLC
;
non-small cell lung cancer
;
PDK1
;
3-phosphoinositide-dependent protein kinase-1
;
PI
;
propidium iodide
;
PI3K
;
phosphatidylinositol-3 kinase
;
SCLC
;
small cell lung cancer
;
SDS-PAGE
;
sodium dodecyl sulfate-polyacrylamide gel electrophoresis
;
S.E.M.
;
standard error of the mean
;
TER
;
transepitheli
刊名:Biochimica et Biophysica Acta (BBA)-Molecular Cell Research
出版年:2016
9.
Locking
PDK1
in DFG-out conformation through 2-oxo-indole containing molecules: Another tools to fight glioblastoma
作者:
Simona Sestito
a
;
1
;
Simona Daniele
a
;
1
;
Giulia Nesi
a
;
Elisa Zappelli
a
;
Danilo Di Maio
b
;
c
;
Luciana Marinelli
d
;
Maria Digiacomo
a
;
Annalina Lapucci
a
;
Claudia Martini
a
;
Ettore Novellino
d
;
Simona Rapposelli
a
;
simona.rapposelli@farm.unipi.it" class="auth_mail" title="E-mail the corresponding author
关键词:
PDK1
inhibitors
;
Kinase inhibitors
;
Oxindole derivatives
;
Pyridonyl derivatives
;
Glioblastoma
;
GBM stem cells
刊名:European Journal of Medicinal Chemistry
出版年:2016
10.
Frequent overexpression of
PDK1
in primary nasopharyngeal carcinoma is associated with poor prognosis
作者:
Guangzao Xiang
a
;
Xianhui Li
b
;
Longhe Cao
b
;
Chuansai Zhu
b
;
Zhijian Dai
b
;
Shenhua Pan
c
;
Sen Lin
b
;
lnns@163.com
关键词:
Primary
;
Nasopharyngeal carcinoma
;
Pyruvate dehydrogenase kinase 1
;
Prognosis
刊名:Pathology - Research and Practice
出版年:2016
1
2
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