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Wiley电子期刊(2)
SpringerLink电子期刊(6)
Elsevier电子期刊(36)
ACS电子期刊(12)
在“
Elsevier电子期刊
”中,
命中:
36
条,耗时:小于0.01 秒
在所有数据库中总计命中:
56
条
1.
Discovery of a novel class of highly potent inhibitors of the p53-MDM2 interaction by structure-based design starting from a conformational argument
作者:
Pascal
Furet
;
pascal
.
furet
@novartis.com" class="auth_mail" title="E-mail the corresponding author
;
Keiichi Masuya
;
Joerg Kallen
;
Thé
;
rè
;
se Stachyra-Valat
;
Stephan Ruetz
;
Vito Guagnano
;
Philipp Holzer
;
Robert Mah
;
Stefan Stutz
;
Andrea Vaupel
;
Patrick Chè
;
ne
;
Sé
;
bastien Jeay
;
Achim Schlapbach
关键词:
p53&ndash
;
MDM2 inhibitors
;
Protein&ndash
;
protein interaction inhibitors
;
Anticancer agents
;
Structure-based design
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2016
2.
Identification of a 5-[3-phenyl-(2-cyclic-ether)-methylether]-4-aminopyrrolo[2,3-d]pyrimidine series of IGF-1R inhibitors
作者:
Fré
;
dé
;
ric Stauffer
;
frederic.stauffer@novartis.com" class="auth_mail" title="E-mail the corresponding author
;
Sandra W. Cowan-Jacob
;
Clemens Scheufler
;
Pascal
Furet
关键词:
IGF-1R inhibitor
;
IGF-1R X-ray co-crystal structure
;
Structure-guided design
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2016
3.
Tetra-substituted imidazoles as a new class of inhibitors of the p53-MDM2 interaction
作者:
Andrea Vaupel
;
andrea.vaupel@novartis.com" class="auth_mail
;
Guido Bold
;
Alain De Pover
;
Thé
;
rè
;
se Stachyra-Valat
;
Joanna Hergovich-Lisztwan
;
Joerg Kallen
;
Keiichi Masuya
;
Pascal
Furet
;
pascal
.
furet
@novartis.com" class="auth_mail
关键词:
Protein&ndash
;
protein interaction inhibitors
;
Structure-based design
;
p53
;
MDM2
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:1 May, 2014
4.
Discovery of NVP-BYL719 a potent and selective phosphatidylinositol-3 kinase alpha inhibitor selected for clinical evaluation
作者:
Pascal
Furet
;
Vito Guagnano
;
Robin A. Fairhurst
;
Patricia Imbach-Weese
;
Ian Bruce
;
Mark Knapp
;
Christine Fritsch
;
Francesca Blasco
;
Joachim Blanz
;
Reiner Aichholz
;
Jacques Hamon
;
Doriano Fabbro
;
Giorgio Caravatti
;
giorgio.caravatti@novartis.com
关键词:
PI3K inhibitors
;
Antitumor agent
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2013
5.
Corrigendum to ¡°Discovery of NVP-BYL719 a potent and selective phosphatidylinositol-3 kinase alpha inhibitor selected for clinical evaluation¡± [Bioorg. Med. Chem. Lett. 23 (2013) 3741-3748]
作者:
Pascal
Furet
;
Vito Guagnano
;
Robin A. Fairhurst
;
Patricia Imbach-Weese
;
Ian Bruce
;
Mark Knapp
;
Christine Fritsch
;
Francesca Blasco
;
Joachim Blanz
;
Reiner Aichholz
;
Jacques Hamon
;
Doriano Fabbro
;
Giorgio Caravatti
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2013
6.
Differential regulation of two sucrose transporters by defoliation and light conditions in perennial ryegrass
作者:
Pierre-Maxime
Furet
1
;
Alexandre Berthier
1
;
Marie-Laure Decau
;
Annette Morvan-Bertrand
;
Marie-
Pascal
e Prud'homme
;
Nathalie Noiraud-Romy
;
Fré
;
dé
;
ric Meuriot
;
frederic.meuriot@unicaen.fr
关键词:
Sucrose
;
Sucrose transporters
;
Lolium perenne L.
;
Regrowth
;
Light
刊名:Plant Physiology and Biochemistry
出版年:2012
7.
New aromatase inhibitors from the 3-pyridyl arylether and 1-aryl pyrrolo[2,3-c]pyridine series
作者:
Fré
;
dé
;
ric Stauffer
;
frederic.stauffer@novartis.com
;
Pascal
Furet
;
Andreas Floersheimer
;
Marc Lang
关键词:
Aromatase
;
CYP19
;
Aromatase inhibition
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2012
8.
The central valine concept provides an entry in a new class of non peptide inhibitors of the p53-MDM2 interaction
作者:
Pascal
Furet
;
pascal
.
furet
@novartis.com
;
Patrick Chè
;
ne
;
Alain De Pover
;
Thé
;
rè
;
se Stachyra Valat
;
Joanna Hergovich Lisztwan
;
Joerg Kallen
;
Keiichi Masuya
关键词:
p53&ndash
;
MDM2 inhibitors
;
Protein&ndash
;
protein interaction inhibitors
;
Anticancer agents
;
Structure-based design
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2012
9.
Discovery and SAR of potent, orally available 2,8-diaryl-quinoxalines as a new class of JAK2 inhibitors
作者:
Carole Pissot-Soldermann
;
Marc Gerspacher
;
Pascal
Furet
;
Christoph Gaul
;
Philipp Holzer
;
Clive McCarthy
;
Thomas Radimerski
;
Catherine H. Regnier
;
Fabienne Baffert
;
Peter Drueckes
;
Gisele A. Tavares
;
E
关键词:
Janus kinase
;
JAK1
;
JAK2
;
JAK3
;
Tyk2
;
Kinase inhibitors
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2010
10.
Design of two new chemotypes for inhibiting the Janus kinase 2 by scaffold morphing
作者:
Pascal
Furet
;
Marc Gerspacher
;
Carole Pissot-Soldermann
关键词:
Scaffold morphing
;
Kinase inhibitor design
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2010
1
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