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内部出版物
Wiley电子期刊(2)
NATURE电子期刊(1)
ACS电子期刊(72)
SpringerLink电子期刊(34)
Elsevier电子期刊(378)
在“
Elsevier电子期刊
”中,
命中:
378
条,耗时:0.0979543 秒
在所有数据库中总计命中:
487
条
1.
A combination of sorafenib and SC-4
3
is a synergistic SHP-1 agonist duo to advance hepatocellular carcinoma therapy
作者:
Tzu-I Chao
a
;
1
;
Wei-Tien Tai
a
;
b
;
1
;
Man-Hsin Hung
c
;
d
;
1
;
Ming-Hsien Tsai
a
;
Min-Hsuan Chen
a
;
Mao-Ju Chang
a
;
Chung-Wai Shiau
e
;
Kuen-Feng Chen
a
;
b
;
kfchen1970@ntu.edu.tw" class="auth_mail" title="E-mail the corresponding author
关键词:
HCC
;
hepatocellular carcinoma
;
SHP-1
;
Src
homology
region
2 domain containing phosphatase 1
;
STAT
3
;
signal transducer and activator of transcription
3
;
p-STAT
3
;
phosphorylated STAT
3
;
Raf
;
rapidly accelerated fibrosarcoma
;
VEGFR
;
vascular endothelial growth factor receptor
;
PDGFR
;
platelet-derived growth factor receptor
;
PTP
;
protein tyrosine phosphatase
;
SH2
;
Src
homology
region
2
;
DMSO
;
dimethyl sulfoxide
;
DMEM
;
Dulbecco's modified Eagles' medium
;
PARP
;
Poly (ADP-ribose) polymerase
;
Mcl-1
;
myel
刊名:Cancer Letters
出版年:2016
2.
Cool-temperature-mediated activation of phospholipase C-γ
2
in the human hereditary disease PLAID
作者:
Anja Schade
a
;
Claudia Walliser
a
;
Martin Wist
a
;
Jennifer Haas
a
;
Petra Vatter
a
;
Johann M. Kraus
b
;
Davide Filingeri
c
;
1
;
George Havenith
c
;
Hans A. Kestler
b
;
Joshua D. Milner
d
;
Peter Gierschik
a
;
peter.gierschik@uni-ulm.de" class="auth_mail" title="E-mail the corresponding author
关键词:
PLC
;
inositol-phospholipid-specific phospholipase C
;
SH2
;
Src
homology
domain 2
;
SH
3
;
Src
homology
domain
3
;
PH
;
pleckstrin
homology
domain
;
spPH
;
split PH domain
;
PCI
;
phospholipase C inhibitor peptide
;
Rac
;
Ras-related C
3
botulinum toxin substrate
;
BCR
;
B cell receptor
;
SA
;
specific array
;
PLAID
;
PLCγ2-associated antibody deficiency and immune dysregulation
;
TRP
;
transient receptor potential
;
PtdIns
;
phosphatidylinositol
;
PtdIns(4)P
;
phosphatidylinositol 4-phosphate
;
PtdIns(4
;
5)P2
;
phosphatidy
刊名:Cellular Signalling
出版年:2016
3.
Simultaneous regulation of apoptotic gene silencing and angiogenic gene expression for myocardial infarction therapy: Single-carrier delivery of SHP-1 siRNA and VEGF-expressing pDNA
作者:
Dongkyu Kim
a
;
b
;
1
;
Sook Hee Ku
a
;
1
;
Hyosuk Kim
a
;
c
;
Ji Hoon Jeong
a
;
d
;
Minhyung Lee
e
;
Ick Chan Kwon
a
;
d
;
Donghoon Choi
b
;
cdhlyj@yuhs.ac
;
Sun Hwa Kim
a
;
sunkim@kist.re.kr
关键词:
SHP-1 siRNA
;
VEGF plasmid DNA
;
Myocardial ischemia-reperfusion injury
;
Deoxycholic acid-modified polyethylenimine
刊名:Journal of Controlled Release
出版年:2016
4.
Dovitinib Acts As a Novel Radiosensitizer in Hepatocellular Carcinoma by Targeting SHP-1/STAT
3
Signaling
作者:
Chao-Yuan Huang
;
MD
;
PhD
&lowast
;
;
&dagger
;
;
Wei-Tien Tai
;
PhD
&Dagger
;
;
§
;
;
Szu-Yuan Wu
;
MD
‖
;
¶
;
;
#
;
&lowast
;
&lowast
;
;
Chih-Ting Shih
;
MS
&Dagger
;
;
Min-Hsuan Chen
;
MS
&Dagger
;
;
Ming-Hsien Tsai
&Dagger
;
;
Chiung-Wen Kuo
;
PhD
&dagger
;
&dagger
;
;
Chung-Wai Shiau
;
PhD
&Dagger
;
&Dagger
;
;
Man-Hsin Hung
;
MD
§
;
§
;
;
‖‖
;
¶
;
¶
;
;
##
;
cindybeaty@gmail.com" class="auth_mail" title="E-mail the corresponding author
;
Kuen-Feng Chen
;
MD
;
PhD
&Dagger
;
;
§
;
;
kfchen1970@ntu.edu.tw" class="auth_mail" title="E-mail the corresponding author
刊名:International Journal of Radiation Oncology*Biology*Physics
出版年:2016
5.
The alpha secretase ADAM10: A metalloprotease with multiple functions in the brain
作者:
Paul Saftig
a
;
psaftig@biochem.uni-kiel.de" class="auth_mail" title="E-mail the corresponding author
;
Stefan F. Lichtenthaler
b
;
c
;
stefan.lichtenthaler@dzne.de" class="auth_mail" title="E-mail the corresponding author
关键词:
ADAM
;
A Disintegrin And Metalloproteinase
;
BACE
;
β-site APP cleaving enzyme
;
APP
;
amyloid precursor protein
;
AD
;
Alzheimer disease
;
RIP
;
regulated intramembrane proteolysis
;
PC
;
prohormone convertase
;
CNS
;
central nervous system
;
UTR
;
untranslated
region
;
SIRT1
;
NAD-dependent deacytylase sirtuin-1
;
PC
;
prohormone convertase
;
ER
;
endoplasmic reticulum
;
SH
3
;
Src
homology
3
-binding domain
;
PACAP
;
pituitary adenylate cyclase-activating polypeptide
;
MAPK
;
mitogen activated protein kinase
;
SAP97
;
syna
刊名:Progress in Neurobiology
出版年:2015
6.
The zinc-binding
region
of IL-2 inducible T cell kinase (Itk) is required for interaction with G¦Á1
3
and activation of serum response factor
作者:
Weishan Huang
a
;
b
;
J. Luis Morales
b
;
Victor P. Gazivoda
a
;
Jianbin Lai
c
;
Qian Qi
a
;
b
;
1
;
Avery August
a
;
b
;
averyaugust@cornell.edu
关键词:
G-protein
;
guanine nucleotide binding protein
;
GFP
;
green fluorescent protein
;
Itk
;
inducible T cell kinase
;
PH
;
pleckstrin
homology
domain
;
PRR
;
proline rich
region
;
TcR
;
T cell receptor
;
TH
;
Tec
homology
domain
;
SH2
;
Src
homology
domain 2
;
SH
3
;
Src
homo
刊名:The International Journal of Biochemistry and Cell Biology
出版年:201
3
7.
PLEKHG2/FLJ00018, a Rho family-specific guanine nucleotide exchange factor, is tyrosine phosphorylated via the EphB2/c
Src
signaling pathway
作者:
Katsuya Sato
;
Takahiro Suzuki
;
Yoshihiro Yamaguchi
;
Yukio Kitade
;
Takahiro Nagase
;
Hiroshi Ueda
关键词:
DH
;
dbl
homology
;
DHR
;
dock
homology
region
;
DMEM
;
Dulbecco's modified Eagle's medium
;
Eph
;
ephrin receptor
;
FBS
;
fetal bovine serum
;
GAP
;
GTPase activating protein
;
G-protein
;
guanosine triphosphate-binding protein
;
GPCR
;
heterotrimeric G-protein-coupled receptor
;
PBS
;
phosphate-buffered saline
;
PDZ
;
post synaptic density protein
;
Drosophila disc large tumor suppressor and zonula occludens-1 protein
;
PH
;
pleckstrin
homology
;
Rho
;
rho family small G-protein
;
RhoGEF
;
Rho-specific guanine nucleoti
刊名:Cellular Signalling
出版年:April, 2014
8.
Inhibition of IL-6 family cytokines by SOCS
3
作者:
Jeffrey J. Babon
a
;
b
;
babon@wehi.edu.au" class="auth_mail
;
Leila N. Varghese
a
;
b
;
Nicos A. Nicola
a
;
b
关键词:
JAKs
;
Janus Kinases
;
SOCS
;
Suppressor of Cytokine Signalling
;
STAT
;
Signal Transducers and Activators of Transcription
;
IL-6
;
interleukin-6
;
IL-10
;
interleukin-10
;
IL-11
;
interleukin-11
;
IL-27
;
interleukin-27
;
gp1
3
0
;
glycoprotein 1
3
0
;
OSM
;
oncostatin M
;
LIF
;
leukemia inhibitory factor
;
CNTF
;
cillary neurotrophic factor
;
CT-1
;
cardiotrophin 1
;
IL-6R伪
;
interleukin-6 receptor alpha-chain
;
G-CSF
;
granulocyte colony-stimulating factor
;
KIR
;
kinase inhibitory
region
;
SH2
;
Src
homology
2
;
SHP2
;
SH2 do
刊名:Seminars in Immunology
出版年:February, 2014
9.
Functional conservation of suppressors of cytokine signaling proteins between teleosts and mammals: Atlantic salmon SOCS1 binds to JAK/STAT family members and suppresses type I and II IFN signaling
作者:
Astrid Skjesol
a
;
1
;
Theresa Liebe
a
;
b
;
1
;
Dimitar B. Iliev
a
;
Ernst I.S. Thomassen
a
;
Linn Greiner Tollersrud
a
;
Mehrdad Sobhkhez
a
;
Lisbeth Lindenskov Joensen
a
;
Christopher J. Secombes
c
;
Jorunn B. Jø
;
rgensen
a
;
jorunn.jorgensen@uit.no" class="auth_mail
关键词:
bp
;
base pair
;
JAK
;
Janus kinase
;
Tyk2
;
tyrosine kinase 2
;
IFN
;
interferon
;
JAB
;
JAK-binding protein
;
SH2
;
SRC
-
homology
2
;
ESS
;
extended SH2 domain
;
KIR
;
kinase inhibitory
region
;
SOCS
;
suppressors of cytokine signaling
;
STAT
;
signal transducers and activators of the transcription
;
SSI
;
STAT-induced STAT-inhibitor
;
JH
;
Janus
homology
;
ODNs
;
oligodeoxynucleotides
;
MOI
;
multiplicity of infection
;
ISGs
;
interferon responsive genes
;
ISRE
;
interferon stimulated response element
刊名:Developmental and Comparative Immunology
出版年:July, 2014
10.
Nintedanib (BIBF-1120) inhibits hepatocellular carcinoma growth independent of angiokinase activity
作者:
Wei-Tien Tai
1
;
2
;
&dagger
;
;
Chung-Wai Shiau
3
;
&dagger
;
;
Yong-Shi Li
1
;
2
;
Chun-Wei Chang
1
;
2
;
Jui-Wen Huang
4
;
Ting-Ting Hsueh
3
;
Hui-Chuan Yu
1
;
2
;
Kuen-Feng Chen
1
;
2
;
kfchen1970@ntu.edu.tw" class="auth_mail
关键词:
HCC
;
hepatocellular carcinoma
;
Ab
;
antibody
;
IP
;
immunoprecipitation
;
p-STAT
3
;
phosphorylated STAT
3
;
PTPs
;
protein tyrosine phosphatases
;
SH2
;
Src
homology
region
2
;
SHP-1
;
SH2 domain-containing phosphatase 1
;
STAT
3
;
signal transducer and activator of transcription
3
;
VEGF
;
vascular endothelial growth factor receptor
;
VEGFR
;
vascular endothelial growth factor receptor
;
WT
;
wild type
刊名:Journal of Hepatology
出版年:July 2014
1
2
3
4
5
6
7
8
9
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