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在“
Elsevier电子期刊
”中,
命中:
3,077
条,耗时:0.1369363 秒
在所有数据库中总计命中:
5,177
条
1.
Optimization and bioevaluation of Cdc37-derived peptides: An insight into Hsp90-Cdc37
protein
-
protein
interaction
modulators
作者:
Lei Wang
a
;
b
;
Li Li
a
;
b
;
Wei-Tao Fu
c
;
Zheng-Yu Jiang
a
;
b
;
Qi-Dong You
a
;
b
;
youqidong@gmail.com
;
Xiao-Li Xu
a
;
b
;
xiaoli_xu@126.com
关键词:
Protein
-
protein
interaction
;
Hsp90-Cdc37 PPI
;
Hot-spots
;
Peptides
;
MD simulation
刊名:Bioorganic & Medicinal Chemistry
出版年:2017
2.
Design, synthesis and structure-activity relationship of 4,5-dihydropyrrolo[3,4-c]pyrazol-6(1H)-ones as potent p53-MDM2
inhibitors
作者:
Wei-Huang Zhou
a
;
b
;
Xi-Guo Xu
a
;
b
;
Jin Li
b
;
Xiao Min
b
;
Jian-Zhong Yao
b
;
Guo-Qiang Dong
b
;
Chun-Lin Zhuang
b
;
zclnathan@163.com
;
Zhen-Yuan Miao
b
;
miaozhenyuan@hotmail.com
;
Wan-Nian Zhang
a
;
b
;
zhangwnk@hotmail.com
关键词:
p53-MDM2
;
Protein
&ndash
;
protein
interaction
;
Inhibitors
;
Drug design
;
Structure&ndash
;
activity relationships
;
Antiproliferative
刊名:Chinese Chemical Letters
出版年:2017
3.
Identification and validation of small molecule modulators of the NusB-NusE
interaction
作者:
Peter J. Cossar
a
;
3
;
Cong Ma
b
;
2
;
3
;
Christopher P. Gordon
a
;
1
;
Joseph I. Ambrus
a
;
Peter J. Lewis
b
;
Adam McCluskey
a
;
Adam.McCluskey@newcastle.edu.au
关键词:
Protein
-
protein
interaction
;
NusB-NusE
;
Antibiotic
;
Pharmacophore
;
In silico screening
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2017
4.
Systematic Identification of Oncogenic EGFR
Interaction
Partners
作者:
Julia Petschnigg
1
;
Max Kotlyar
2
;
Louise Blair
1
;
Igor Jurisica
2
;
3
;
4
;
5
;
Igor Stagljar
6
;
7
;
8
;
Robin Ketteler
1
;
r.ketteler@ucl.ac.uk
关键词:
EGF
;
epidermal growth factor
;
EGFR
;
epidermal growth factor receptor
;
ERK
;
extracellular signal-regulated kinase
;
GFP
;
green fluorescent
protein
;
Grb2
;
growth factor receptor-bound
protein
2
;
SH
;
Src homology
;
MAPK
;
mitogen-activated
protein
kinase
;
TK
;
tyrosine kinase
;
TKI
;
TK inhibitor
;
NSCLC
;
non-small cell lung cancer
;
MaMTH
;
mammalian membrane two-hybrid
;
TACC
;
transforming acidic coiled-coil
protein
;
GO
;
gene ontology
;
Cub
;
C-terminal half of ubiquitin
;
TF
;
transcription factor
;
Nub
;
N-ter
刊名:Journal of Molecular Biology
出版年:2017
5.
Design, synthesis and biological evaluation of 7-(aryl)-2,3-dihydro-[1,4]dioxino[2,3-g]quinoline derivatives as potential Hsp90
inhibitors
and anticancer agents
作者:
Sina Omid Malayeri
a
;
b
;
Khalil Abnous
c
;
Atefeh Arab
d
;
Maryam Akaberi
e
;
Soghra Mehri
c
;
Afshin Zarghi
f
;
Razieh Ghodsi
a
;
b
;
ghodsir@mums.ac.ir
关键词:
Quinolines
;
Heat Shock
Protein
90
;
Anti-cancer activity
;
Her2
;
Molecular docking
;
Hsp90 inhibitor
刊名:Bioorganic & Medicinal Chemistry
出版年:2017
6.
Acyl chain preference and inhibitor identification of Moraxella catarrhalis LpxA: Insight through crystal structure and computational studies
作者:
Shivendra Pratap
;
Pooja Kesari
;
Ravi Yadav
;
Aditya Dev
;
Manju Narwal
;
Pravindra Kumar
;
pravshai@gmail.com
关键词:
UDP-N-acetylglucosamine acyltransferase
;
Crystal structure
;
Hydrocarbon ruler
;
Virtual screening
;
Acyl carrier
protein
刊名:International Journal of Biological Macromolecules
出版年:2017
7.
Natural NO
inhibitors
from the leaves of Callicarpa kwangtungensis: Structures, activities, and
interaction
s with iNOS
作者:
Shen Li
a
;
Xiaocong Sun
a
;
Yang Li
a
;
Feng Liu
a
;
Jun Ma
a
;
Ling Tong
b
;
Guochen Su
a
;
Jing Xu
a
;
xujing611@nankai.edu.cn
;
Yasushi Ohizumi
c
;
Dongho Lee
d
;
Yuanqiang Guo
a
;
victgyq@nankai.edu.cn
关键词:
Callicarpa kwangtungensis
;
9
;
10-seco-Abietane diterpenoid
;
NO inhibitory activities
;
iNOS
;
Molecular docking
;
Terpenoids
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2017
8.
Synthesis, structure-activity relationship and molecular docking of 3-oxoaurones and 3-thioaurones as acetylcholinesterase and butyrylcholinesterase
inhibitors
作者:
Ehsan Ullah Mughal
a
;
ehsan.ullah@uog.edu.pk
;
Amina Sadiq
b
;
Shahzad Murtaza
a
;
Hummera Rafique
a
;
Muhammad Naveed Zafar
c
;
Tauqeer Riaz
a
;
Bilal Ahmad Khan
d
;
Abdul Hameed
e
;
Khalid Mohammed Khan
e
关键词:
Flavonoids
;
Aurones
;
3-Thioaurones
;
Lawesson&rsquo
;
s reagent
;
AChE/BChE
inhibitors
;
Molecular docking studies
刊名:Bioorganic & Medicinal Chemistry
出版年:2017
9.
Design, synthesis, and characterization of rhein analogs as novel
inhibitors
of scavenger receptor A
作者:
Yi Zheng
a
;
1
;
Xia Li
b
;
1
;
Piyusha P. Pagare
a
;
Yunyun Yuan
a
;
Xiang-Yang Wang
b
;
c
;
d
;
xywang@vcu.edu
;
Yan Zhang
a
;
d
;
yzhang2@vcu.edu
关键词:
Scavenger receptor A
;
Rhein
;
Danthron
;
Cancer immunotherapy
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2017
10.
New insights on molecular
interaction
s of organophosphorus pesticides with esterases
作者:
Iris Mangas
a
;
imangas@umh.es
;
Jorge Estevez
b
;
Eugenio Vilanova
b
;
Tanos Celmar Costa Franç
;
a
a
;
c
;
d
关键词:
Organophosphorus compounds
;
pesticides
;
mass spectrometry
;
in silico
;
cholinesterases
;
alpha/beta hydrolases
刊名:Toxicology
出版年:2017
1
2
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5
6
7
8
9
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