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Wiley电子期刊(8)
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ACS电子期刊(5)
SpringerLink电子期刊(34)
Elsevier电子期刊(96)
在“
Elsevier电子期刊
”中,
命中:
96
条,耗时:小于0.01 秒
在所有数据库中总计命中:
155
条
1.
In Silico Meets In Vivo: Towards Computational CRISPR-Based
sgRNA
Design
作者:
Guo-hui Chuai
1
;
3
;
Qi-Long Wang
2
;
3
;
Qi Liu
1
;
qiliu@tongji.edu.cn
关键词:
CRISPR
;
in silico
sgRNA
design
;
off-target
;
genome editing
刊名:Trends in Biotechnology
出版年:2017
2.
C2c1-
sgRNA
Complex Structure Reveals RNA-Guided DNA Cleavage Mechanism
作者:
Liang Liu
1
;
Peng Chen
1
;
2
;
Min Wang
1
;
Xueyan Li
1
;
2
;
Jiuyu Wang
1
;
Maolu Yin
1
;
2
;
Yanli Wang
1
;
2
;
3
;
4
;
ylwang@ibp.ac.cn
关键词:
CRISPR-Cas system
;
C2c1
;
crystal structure
;
DNA endonuclease
;
genome-editing
刊名:Molecular Cell
出版年:2017
3.
A novel
sgRNA
selection system for CRISPR-Cas9 in mammalian cells
作者:
Haiwei Zhang
a
;
Xixi Zhang
a
;
Cunxian Fan
a
;
Qun Xie
a
;
b
;
Chengxian Xu
a
;
Qun Zhao
a
;
Yongbo Liu
a
;
Xiaoxia Wu
a
;
Haibing Zhang
a
;
hbzhang@sibs.ac.cn" class="auth_mail" title="E-mail the corresponding author
关键词:
CRISPR/Cas9
;
sgRNA
selection
;
Gene knockout
;
Necroptosis
;
Cell death
刊名:Biochemical and Biophysical Research Communications
出版年:2016
4.
Insert, remove or replace: A highly advanced genome editing system using CRISPR/Cas9
作者:
S. Antony Ceasar
a
;
b
;
1
;
Vinothkumar Rajan
c
;
1
;
Sergey V. Prykhozhij
d
;
1
;
Jason N. Berman
c
;
d
;
Jason.berman@iwk.nshealth.ca" class="auth_mail" title="E-mail the corresponding author
;
S. Ignacimuthu
a
;
e
;
eriloyola@hotmail.com" class="auth_mail" title="E-mail the corresponding author
关键词:
Genome editing
;
CRISPR
;
Cas9
;
Mutation
;
Indel
;
sgRNA
;
Double stranded breaks
刊名:Biochimica et Biophysica Acta (BBA)-Molecular Cell Research
出版年:2016
5.
Pseudorabies virus can escape from CRISPR-Cas9-mediated inhibition
作者:
Zhiyuan Peng
1
;
Ting Ouyang
1
;
Daxin Pang
1
;
Teng Ma
;
Xinrong Chen
;
Ning Guo
;
Fuwang Chen
;
Lin Yuan
;
Hongsheng Ouyang
;
Linzhu Ren
;
renlz@jlu.edu.cn" class="auth_mail" title="E-mail the corresponding author
关键词:
Pseudorabies virus (PRV)
;
CRISPR/Cas9
;
Single-guide RNA (
sgRNA
)
;
UL30 protein
;
Inhibition
;
Escape
刊名:Virus Research
出版年:2016
6.
Tandem repeat knockout utilizing the CRISPR/Cas9 system in human cells
作者:
Qingyan Lv
1
;
Liangxue Lai
1
;
Lin Yuan
;
Yuning Song
;
Tingting Sui
;
Zhanjun Li
;
lizj_1998@jlu.edu.cn" class="auth_mail" title="E-mail the corresponding author
关键词:
sgRNA
;
Single guide RNA
;
Humanized Cas9
;
hCas9
;
Humanized S. pyogenes
;
hSpCas9
;
Double-strand DNA breaks
;
DSBs
;
Tandem repeat units
;
TRs
;
Potential off-target sites located in the genome
;
POTS
;
Off-target sites located in the TRs
;
OTS
;
Protospacer adjacent motif
;
PAM
刊名:Gene
出版年:2016
7.
Expansion of CRISPR targeting sites in Bombyx mori
作者:
Baosheng Zeng
a
;
b
;
Shuai Zhan
a
;
Yueqiang Wang
a
;
Yuping Huang
a
;
Jun Xu
a
;
b
;
Qun Liu
a
;
Zhiqian Li
a
;
Yongping Huang
a
;
yphuang@sibs.ac.cn" class="auth_mail" title="E-mail the corresponding author
;
Anjiang Tan
a
;
ajtan01@sibs.ac.cn" class="auth_mail" title="E-mail the corresponding author
关键词:
CRISPR/Cas9
;
U6 promoter
;
sgRNA
;
Transgene
;
Bombyx mori
刊名:Insect Biochemistry and Molecular Biology
出版年:2016
8.
CRISPR/Cas9 knockout of HAS2 in rat chondrosarcoma chondrocytes demonstrates the requirement of hyaluronan for aggrecan retention
作者:
Yi Huang
;
Emily B. Askew
;
Cheryl B. Knudson
;
Warren Knudson
;
knudsonw@ecu.edu
关键词:
OA
;
osteoarthritis
;
ECM
;
extracellular matrix
;
HA
;
hyaluronan
;
HAS2
;
hyaluronan synthase-2
;
RCS
;
rat chondrosarcoma
;
sgRNA
;
single guide RNA
;
sGAG
;
sulfated glycosaminoglycan
;
DMMB
;
dimethylmethylene blue
刊名:Matrix Biology
出版年:2016
9.
PAM-Dependent Target DNA Recognition and Cleavage by C2c1 CRISPR-Cas Endonuclease
作者:
Hui Yang
1
;
yangh3@mskcc.org
;
Pu Gao
1
;
2
;
Kanagalaghatta R. Rajashankar
3
;
4
;
Dinshaw J. Patel
1
;
5
;
pateld@mskcc.org
关键词:
type V CRISPR-Cas endonuclease
;
C2c1
;
structure
;
binary complex with
sgRNA
;
ternary complex with added DNA
;
RuvC catalytic pocket
;
sequence-specific PAM recognition
;
genome editing tool
刊名:Cell
出版年:2016
10.
CRISPR interference-guided balancing of a biosynthetic mevalonate pathway increases terpenoid production
作者:
Seong Keun Kim
a
;
b
;
Gui Hwan Han
a
;
Wonjae Seong
a
;
b
;
Haseong Kim
a
;
b
;
Seon-Won Kim
c
;
Dae-Hee Lee
a
;
b
;
dhlee@kribb.re.kr" class="auth_mail" title="E-mail the corresponding author
;
Seung-Goo Lee
a
;
b
;
sglee@kribb.re.kr" class="auth_mail" title="E-mail the corresponding author
关键词:
CRISPR
;
Clustered regularly interspaced short palindromic repeats
;
CRISPRi
;
Clustered regularly interspaced short palindromic repeats interference
;
MVA
;
mevalonate
;
sgRNA
;
single guide RNA
;
dCas9
;
inactive Cas9
;
IPP
;
isopentenyl diphosphate
;
DMAPP
;
dimethylallyl diphosphate
;
MEP
;
methylerythritol 4-phosphate
;
DXP
;
1-deoxy-D-xylulose 5-phosphate
;
HMG-CoA
;
3-hydroxy-3-methyl-glutaryl-CoA
;
LB
;
Luria-Bertani
;
TB
;
terrific broth
;
PCR
;
polymerase chain reaction
;
UTR
;
untranslated region
;
T7RNAP
;
T7 RN
刊名:Metabolic Engineering
出版年:2016
1
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