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Elsevier电子期刊(519)

在“Elsevier电子期刊”中，命中：519条，耗时：小于0.01 秒

在所有数据库中总计命中：546条

1.Synthesis, physicochemical and biological studies of technetium-99m labeled tacrine derivative as a diagnostic tool for evaluation of cholinesterase level

作者：Ewa Gniazdowska^a ; Przemysław Koźmiński^a ; ^{p.kozminski@ichtj.waw.pl} ; Marek Wasek^b ; Marek Bajda^c ; Joanna Sikora^d ; Elżbieta Mikiciuk-Olasik^e ; Paweł Szymański^f ; ^{pawel.szymanski@umed.lodz.pl}

关键词：Tac ; tacrine (123 ; 4-tetrahydroacridin-9-amine) ; AD ; Alzheimer&rsquo ; s disease ; AChE ; acetylcholinesterase ; CNS ; central nervous system ; IC50 ; half maximal inhibitory concentration ; BM ; biologically active molecule ; BFCA ; Bifunctional Coupling Agent ; NS3 ; tris(2-mercaptoethyl)-amine ; CN-BFCA ; isocyanobutyric acid succinimidyl ester ; n.c.a. ; no carrier added ; HPLC ; high-performance liquid chromatography ; RT ; retention time ; PBS ; phosphate buffered saline ; TFA ; trifluoroacetic acid ; RCP ; radioche

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

2.Novel tacrine-1,2,3-triazole hybrids: In vitro, in vivo biological evaluation and docking study of cholinesterase inhibitors

作者：Zahra Najafi^a ; Mohammad Mahdavi^b ; Mina Saeedi^c ; ^d ; Elahe Karimpour-Razkenari^d ; Raymond Asatouri^e ; Fahimeh Vafadarnejad^a ; Farshad Homayouni Moghadam^f ; Mahnaz Khanavi^g ; Mohammad Sharifzadeh^h ; ^{msharifzadeh@tums.ac.ir} ; Tahmineh Akbarzadeh^a ; ^d ; ^{akbarzad@tums.ac.ir}

关键词：Alzheimer's disease ; Cholinesterase ; Docking study ; Dual binding ; Morris water maze ; Tacrine-12 ; 3-triazole

刊名：European Journal of Medicinal Chemistry

出版年：2017

3.Tacrine-resveratrol fused hybrids as multi-target-directed ligands against Alzheimer's disease

作者：Jakub Jeřá ; bek^a ; ^b ; Elisa Uliassi^a ; Laura Guidotti^a ; Jan Korá ; bečný ; ^c ; ^d ; Ondřej Soukup^c ; ^d ; Vendula Sepsova^e ; Martina Hrabinova^e ; Kamil Kuča^c ; ^d ; Manuela Bartolini^a ; Luis Emiliano Peñ ; a-Altamira^a ; Sabrina Petralla^a ; Barbara Monti^a ; Marinella Roberti^a ; ^{marinella.roberti@unibo.it} ; Maria Laura Bolognesi^a ; ^{marialaura.bolognesi@unibo.it}

关键词：Alzheimer's disease ; Amyloid ; Acetylcholinesterase ; Multitarget compounds ; Neuroinflammation

刊名：European Journal of Medicinal Chemistry

出版年：2017

4.DNA-functionlized silver nanoclusters as label-free fluorescent probe for the highly sensitive detection of biothiols and acetylcholinesterase activity

作者：Chunying LiAuthor Vitae ; Chunying Wei ; ^{weichuny@sxu.edu.cn}Author Vitae

关键词：DNA-Ag NCs ; Fluorescence ; Biothiols ; Acetylcholinesterase ; Tacrine

刊名：Sensors and Actuators B: Chemical

出版年：2017

5.Transdermal iontophoretic delivery of tacrine hydrochloride: Correlation between in vitro permeation and in vivo performance in rats

作者：Niketkumar Patel¹ ; Shashank Jain² ; Senshang Lin ; ^{linse@stjohns.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Transdermal iontophoresis ; Alzheimer&rsquo ; s disease ; Tacrine hydrochloride ; In vitro-in vivo correlation ; WinNonlin

刊名：International Journal of Pharmaceutics

出版年：2016

6.The compatibility of Tacrine molecule with poly(n-butylcyanoacrylate) and Chitosan as efficient carriers for drug delivery: A molecular dynamics study

作者：Mahboobeh Eslami^a ; Sousa Javan Nikkhah^b ; Seyed Majid Hashemianzadeh^a ; ^{hashemianzadeh@iust.ac.ir" class="auth_mail" title="E-mail the corresponding author} ; ^{hashemianzadeh@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Seyed Abolfazl Seyed Sajadi^a

关键词：Tacrine ; Molecular dynamics simulation ; Polymeric nanoparticles ; Drug carrier

刊名：European Journal of Pharmaceutical Sciences

出版年：2016

7.Novel eugenol derivatives: Potent acetylcholinesterase and carbonic anhydrase inhibitors

作者：Fevzi Topal^a ; Ilhami Gulcin^b ; ^c ; ^{igulcin@atauni.edu.tr} ; ^{igulcin@yahoo.com} ; Arif Dastan^b ; Murat Guney^d

关键词：Eugenol ; Carbonic anhydrase ; Acetylcholinesterase ; Enzyme purification ; Enzyme inhibition

刊名：International Journal of Biological Macromolecules

出版年：2017

8.Synthesis and structure-activity relationship study of tacrine-based pyrano[2,3-c]pyrazoles targeting AChE/BuChE and 15-LOX

作者：Ladan Pourabdi^a ; Mehdi Khoobi^b ; ^c ; Hamid Nadri^d ; Alireza Moradi^d ; Farshad Homayouni Moghadam^e ; Saeed Emami^f ; Mohammad M. Mojtahedi^a ; ; Ismaeil Haririan^b ; Hamid Forootanfar^g ; Alieh Ameri^h ; Alireza Foroumadi^c ; Abbas Shafiee^c ; ^{ashafiee@ams.ac.ir" class="auth_mail" title="E-mail the corresponding author}

关键词：Acetylcholinesterase ; Butyrylcholinesterase ; 15-Lipoxygenase ; Alzheimer's disease ; Tacrine

刊名：European Journal of Medicinal Chemistry

出版年：2016

9.Convenient synthesis of disubstituted tacrine derivatives via electrophilic and copper induced reactions

作者：Makbule Ekiz^a ; ^b ; Ahmet Tutar^b ; ^{atutar@sakarya.edu.tr" class="auth_mail" title="E-mail the corresponding author} ; Salih Ö ; kten^c ; ^{salihokten@kku.edu.tr" class="auth_mail" title="E-mail the corresponding author}

关键词：Tacrine ; Bromotacrine ; Cyanotacrine ; Lithium-bromine exchange ; Thiomethyltacrine ; Methoxytacrine

刊名：Tetrahedron

出版年：2016

10.Targeting copper(II)-induced oxidative stress and the acetylcholinesterase system in Alzheimer's disease using multifunctional tacrine-coumarin hybrid molecules

作者：Slavka Hamulakova^a ; Patrik Poprac^b ; Klaudia Jomova^c ; Vlasta Brezova^b ; Peter Lauro^c ; Lenka Drostinova^c ; Daniel Jun^d ; Vendula Sepsova^d ; Martina Hrabinova^d ; Ondrej Soukup^e ; Pavol Kristian^a ; Zuzana Gazova^f ; ^g ; Zuzana Bednarikova^a ; ^f ; Kamil Kuca^e ; ^h ; Marian Valko^b ; ^h ; ^{marian.valko@stuba.sk" class="auth_mail" title="E-mail the corresponding author}

关键词：Free copper ; Tacrine-coumarin hybrids ; Alzheimer's disease ; Oxidative stress ; DNA damage

刊名：Journal of Inorganic Biochemistry

出版年：2016

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