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在“Elsevier电子期刊”中，命中：5条，耗时：0.1369349 秒

1.Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2α, IRE1α, ATF6 and calmodulin kinase

作者：Angelica M. Merlot^a ; ¹ ; Nurul H. Shafie^a ; ^b ; ¹ ; Yu Yu^a ; Vera Richardson^a ; Patric J. Jansson^a ; Sumit Sahni^a ; Darius J.R. Lane^a ; Zaklina Kovacevic^a ; Danuta S. Kalinowski^a ; ² ; ^{danutak@med.usyd.edu.au" class="auth_mail" title="E-mail the corresponding author} ; Des R. Richardson^a ; ² ; ^{d.richardson@med.usyd.edu.au" class="auth_mail" title="E-mail the corresponding author}

关键词：ASK1 ; apoptosis signal-regulating kinase 1 ; ATF4 ; activating transcription factor 4 ; ATF6 ; activating transcription factor 6 ; BiP ; binding immunoglobulin protein ; BSO ; buthionine sulfoximine ; Ca2+ ; calcium ; CaMKII ; Ca2+/calmodulin-dependent protein kinase II ; CHOP ; C/EBP homologous protein ; DFO ; desferrioxamine ; Dp2mT ; di-2-pyridylketone 2-methyl-3-thiosemicarbazone ; Dp44mT ; di-2-pyridylketone 4 ; 4-dimethyl-3-thiosemicarbazone ; DpT ; di-2-pyridylketone thiosemicarbazone ; eIF2α ; eukaryotic initiati

刊名：Biochemical Pharmacology

出版年：2016

2.Roads to melanoma: Key pathways and emerging players in melanoma progression and oncogenic signaling

作者：Jasmina Paluncic ; Zaklina Kovacevic ; Patric J. Jansson ; Danuta Kalinowski ; Angelika M. Merlot ; Michael L.-H. Huang ; Hiu Chuen Lok ; Sumit Sahni ; Darius J.R. Lane ; ^{darius.lane@sydney.edu.au" class="auth_mail" title="E-mail the corresponding author} ; Des R. Richardson ; ^{d.richardson@med.usyd.edu.au" class="auth_mail" title="E-mail the corresponding author}

关键词：Melanoma ; MAPK ; WNT ; PI3K ; BRAF ; EMT

刊名：Biochimica et Biophysica Acta (BBA)-Molecular Cell Research

出版年：2016

3.Redox cycling metals: Pedaling their roles in metabolism and their use in the development of novel therapeutics

作者：Danuta S. Kalinowski^a ; ¹ ; ^{danutak@med.usyd.edu.au" class="auth_mail" title="E-mail the corresponding author} ; Christian Stefani^a ; ¹ ; Shinya Toyokuni^b ; Tomas Ganz^c ; Gregory J. Anderson^d ; Nathan V. Subramaniam^e ; Debbie Trinder^f ; John K. Olynyk^g ; ^h ; ⁱ ; Anita Chua^f ; Patric J. Jansson^a ; Sumit Sahni^a ; Darius J.R. Lane^a ; Angelica M. Merlot^a ; Zaklina Kovacevic^a ; Michael L.H. Huang^a ; C. Soon Lee^j ; ^k ; ^l ; Des R. Richardson^a ; ^{d.richardson@med.usyd.edu.au" class="auth_mail" title="E-mail the corresponding author}

刊名：Biochimica et Biophysica Acta (BBA)-Molecular Cell Research

出版年：2016

4.Identification of differential anti-neoplastic activity of copper bis(thiosemicarbazones) that is mediated by intracellular reactive oxygen species generation and lysosomal membrane permeabilization

作者：Christian Stefani ; Zaynab Al-Eisawi ; Patric J. Jansson ; Danuta S. Kalinowski ; ^{danutak@med.usyd.edu.au" class="auth_mail" title="E-mail the corresponding author} ; Des R. Richardson ; ^{d.richardson@med.usyd.edu.au" class="auth_mail" title="E-mail the corresponding author}

关键词：Copper ; Bis(thiosemicarbazone) ; Reactive oxygen species ; Lysosome ; Lysosomal membrane permeabilization

刊名：Journal of Inorganic Biochemistry

出版年：2015

5.The renaissance of polypharmacology in the development of anti-cancer therapeutics: Inhibition of the 鈥淭riad of Death鈥?in cancer by Di-2-pyridylketone thiosemicarbazones

作者：Patric J. Jansson¹ ; ^{patric.jansson@sydney.edu.au" class="auth_mail" title="E-mail the corresponding author} ; Danuta S. Kalinowski ; Darius J.R. Lane ; Zaklina Kovacevic ; Nicole A. Seebacher ; Leyla Fouani ; Sumit Sahni ; Angelica M. Merlot ; Des R. Richardson¹ ; ^{d.richardson@med.usyd.edu.au" class="auth_mail" title="E-mail the corresponding author}

关键词：Polypharmacology ; Metastasis ; Tumor growth ; Resistance ; Thiosemicarbazones ; DpC

刊名：Pharmacological Research

出版年：2015

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