搜索页_ r-taguchi@hhc.eisai.co.jp class= auth_mail title= E-mail the corresponding author

设为首页

收藏本站

网站地图 | English | 公务邮箱

About the library

Background
History
Leadership
Organization

Readers' Guide

Opening Hours
Collections
Help Via Email

Publications

Electronic Information Resources

常用资源

在“Elsevier电子期刊”中，命中：10条，耗时：0.2238625 秒

1.Investigation of utility of cerebrospinal fluid drug concentration as a surrogate for interstitial fluid concentration using microdialysis coupled with cisternal cerebrospinal fluid sampling in wild-type and Mdr1a(−/−) rats

作者：Yoko Nagaya^a ; ^{y-nagaya@hhc.eisai.co.jp" class="auth_mail" title="E-mail the corresponding author} ; Yoshitane Nozaki^a ; Osamu Takenaka^b ; Ryuji Watari^a ; Kazutomi Kusano^a ; Tsutomu Yoshimura^a ; Hiroyuki Kusuhara^c

关键词：P-glycoprotein ; Central nervous system ; Brain ; Cerebrospinal fluid ; Interstitial fluid ; Microdialysis ; Rats ; Drug discovery

刊名：Drug Metabolism and Pharmacokinetics

出版年：2016

2.Pharmacological effects of lysozyme on COPD and bronchial asthma with sputum: A randomized, placebo-controlled, small cohort, cross-over study

作者：Hiroyuki Ohbayashi^a ; Yasuhiro Setoguchi^b ; Yoshinosuke Fukuchi^c ; Kai Shibata^d ; ^{k4-shibata@hhc.eisai.co.jp" class="auth_mail" title="E-mail the corresponding author} ; Yukinori Sakata^d ; Toshihisa Arai^d

关键词：Chronic obstructive pulmonary disease (COPD) management ; Bronchial asthma (BA) ; Spirometry ; Mucolytic agent ; Lysozyme ; Impulse oscillometry system (IOS)

刊名：Pulmonary Pharmacology & Therapeutics

出版年：2016

3.Selective corticotropin-releasing factor 1 receptor antagonist E2508 has potent antidepressant-like and anxiolytic-like properties in rodent models

作者：Ryota Taguchi^a ; ^c ; ^{r-taguchi@hhc.eisai.co.jp" class="auth_mail" title="E-mail the corresponding author} ; Kodo Shikata^a ; Yoshiaki Furuya^a ; Mitsuhiro Ino^a ; ^d ; Kogyoku Shin^b ; Hisashi Shibata^a ; ^e

关键词：ACTH ; adrenocorticotropic hormone ; CRF ; corticotropin-releasing factor ; E2508 ; N-cyclopropylmethyl-7-(2 ; 6-dimethoxy-4-methoxymethylphenyl)-2-ethyl-N-(tetrahydro-2H-pyran-4-ylmethyl)pyrazolo[1 ; 5-a]pyridin-3-amine tosylate ; HPA ; hypothalamic-pituitary-adrenal ; IBS ; irritable bowel syndrome ; MDD ; major depressive disorder ; R121919 ; 3-[6-(dimethylamino)-4-methyl-pyrid-3-yl]-2 ; 5-dimethyl-N ; N-dipropyl-pyrazolo[2 ; 3-a]pyrimidin-7-amine ; SSRI ; selective serotonin reuptake inhibitor

刊名：Behavioural Brain Research

出版年：2016

4.Structure, activity and uptake mechanism of siRNA-lipid nanoparticles with an asymmetric ionizable lipid

作者：Yuta Suzuki ; ^{y14-suzuki@hhc.eisai.co.jp" class="auth_mail" title="E-mail the corresponding author} ; Hiroshi Ishihara

关键词：Drug delivery ; Gene silencing ; siRNA ; Lipid nanoparticles ; Nanomedicines

刊名：International Journal of Pharmaceutics

出版年：2016

5.Eribulin versus dacarbazine in previously treated patients with advanced liposarcoma or leiomyosarcoma: a randomised, open-label, multicentre, phase 3 trial

作者：Prof Patrick Schö ; ffski ; MD^a ; ^{patrick.schoffski@uzleuven.be" class="auth_mail" title="E-mail the corresponding author} ; Sant Chawla ; MD^b ; Prof Robert G Maki ; MD^c ; Antoine Italiano ; MD^d ; Prof Hans Gelderblom ; MD^e ; Edwin Choy ; MD^f ; Giovanni Grignani ; MD^g ; Veridiana Camargo ; MD^h ; Sebastian Bauer ; MDⁱ ; Sun Young Rha ; MD^j ; Prof Jean-Yves Blay ; MD^k ; Peter Hohenberger ; MD^l ; David D'Adamo ; MD^m ; Matthew Guo ; PhD^m ; Bartosz Chmielowski ; MDⁿ ; Axel Le Cesne ; MD^o ; Prof George D Demetri ; MD^p ; Prof Shreyaskumar R Patel ; MD^q

刊名：The Lancet

出版年：2016

6.siRNA-lipid nanoparticles with long-term storage stability facilitate potent gene-silencing in vivo

作者：Y. Suzuki^a ; ^{y14-suzuki@hhc.eisai.co.jp" class="auth_mail" title="E-mail the corresponding author} ; K. Hyodo^a ; Y. Tanaka^b ; H. Ishihara^a

关键词：Drug delivery ; Gene silencing ; RNA therapeutics ; siRNA ; Lipid nanoparticles

刊名：Journal of Controlled Release

出版年：2015

7.Wif1 and Ifitm3 gene expression preferentially altered in the colon mucosa of benzo[a]pyrene pre-treated mice following exposure to dextran sulfate sodium

作者：Naoki Koyama^a ; ^{n3-koyama@hhc.eisai.co.jp" class="auth_mail" title="E-mail the corresponding author} ; Atsushi Hakura^a ; Naoki Toritsuka^a ; Jiro Sonoda^a ; Yuki Seki^a ; Osamu Tohyama^b ; Shoji Asakura^a ; Kyoko Nakano-Ito^a ; Satoru Hosokawa^a

关键词：Benzo[a]pyrene ; Dextran sulfate sodium ; Colon ; Gene expression ; Wif1 ; Ifitm3

刊名：Chemico-Biological Interactions

出版年：2015

8.MGMT inactivation and clinical response in newly diagnosed GBM patients treated with Gliadel

作者：Rachel Grossman^a ; Peter Burger^b ; Ethan Soudry^c ; Betty Tyler^a ; ^{btyler@jhmi.edu" class="auth_mail" title="E-mail the corresponding author} ; Kaisorn L. Chaichana^a ; Jon Weingart^a ; ^d ; Alessandro Olivi^a ; ^d ; Gary L. Gallia^a ; ^d ; David Sidransky^d ; Alfredo Quiñ ; ones-Hinojosa^a ; ^d ; Xiaobu Ye^a ; Henry Brem^a ; ^d ; ^e ; ^f

关键词：Gliadel ; Glioblastoma multiforme ; Methylation ; MGMT ; Outcome ; Survival

刊名：Journal of Clinical Neuroscience

出版年：2015

9.Lenvatinib, everolimus, and the combination in patients with metastatic renal cell carcinoma: a randomised, phase 2, open-label, multicentre trial

作者：Dr Robert J Motzer ; MD^a ; ^{motzerr@mskcc.org" class="auth_mail" title="E-mail the corresponding author} ; Thomas E Hutson ; DO^b ; Hilary Glen ; MD^c ; M Dror Michaelson ; MD^d ; Ana Molina ; MD^e ; Prof Timothy Eisen ; FRCP^f ; Prof Jacek Jassem ; MD^g ; Jakub Zolnierek ; MD^h ; Jose Pablo Maroto ; MDⁱ ; Begoñ ; a Mellado ; MD^j ; Prof Bohuslav Melichar ; MD^k ; Jiri Tomasek ; MD^l ; Alton Kremer ; MD^m ; Han-Joo Kim ; PhD^m ; Karen Wood ; PhDⁿ ; Corina Dutcus ; MD^m ; James Larkin ; FRCP^o

刊名：The Lancet Oncology

出版年：2015

10.Gender difference in the progression of Alzheimer’s disease in japanese patients treated with donepezil: Results of the j-gold study

作者：Heii Arai¹ ; Kenta Sumitomo² ; ^{k-sumitomo@hhc.eisai.co.jp" class="auth_mail" title="E-mail the corresponding author} ; Yukinori Sakata² ; Kasumi Daidouji² ; Tetsumi Toyoda³

刊名：Alzheimer's & Dementia

出版年：2015

按检索点细分(10)

作者(7)

按出版年细分(10)

2016年(5)

2015年(5)