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在“Elsevier电子期刊”中，命中：21条，耗时：0.0419792 秒

在所有数据库中总计命中：76条

1.Inhibition of heat shock protein (Hsp) 90 potentiates the antiproliferative and pro-apoptotic effects of 2-(4′fluoro-phenylamino)-4H-1,3-thiazine[6,5-b]indole in A2780cis cells

作者：Zuzana Solá ; rová ; ^a ; Martin Kello^a ; Lenka Varinská ; ^a ; Mariana Budovská ; ^b ; Peter Solá ; r^c ; ^{peter.solar@upjs.sk}

关键词：thiazine[6 ; 5-b]indole ; 2-(4&prime ; fluoro-phenylamino)-4H-1 ; 3-thiazine[6 ; 5-b]indole ; Hsp ; heat shock protein ; 17-DMAG ; 17-dimethylaminoethylamino-17-demethoxygeldanamycin ; 17-AAG ; 17-(allylamino)-17-demethoxygeldanamycin ; A2780 ; human ovarian adenocarcinoma cell line ; A2780cis ; human ovarian adenocarcinoma cell line resistant to cisplatin ; PARP ; poly (ADP-ribose) polymerase ; MMP ; mitochondrial membrane potential ; An ; annexin ; PI ; propidium iodide

刊名：Biomedicine & Pharmacotherapy

出版年：2017

2.Virtual screening and biophysical studies lead to HSP90 inhibitors

作者：Renjie Huang ; Daniel M. Ayine-Tora ; M. Nasri Muhammad Rosdi ; Yu Li ; Jó ; hannes Reynisson ; ^{j.reynisson@auckland.ac.nz} ; Ivanhoe K.H. Leung ; ^{i.leung@auckland.ac.nz}

关键词：17-AAG ; 17-allylamino-17-demethoxygeldanamycin ; 17-DMAG ; 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin (17-DMAG) ; ADP ; adenosine diphosphate ; AMPPCP ; 5&prime ; -adenylylmethylenediphosphonate ; ASP ; Astex statistical potential ; ATP ; adenosine triphosphate ; CS ; ChemScore ; GS ; GoldScore ; HB ; hydrogen bonding ; HSP90 ; heat shock protein 90 ; HSQC ; heteronuclear single quantum correlation ; KD ; binding affinity ; ND ; N-domain ; NMR ; nuclear magnetic resonance ; NOE ; nuclear Overhauser effect ; Tm ; pro

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

3.Inhibition of HIF Reduces Bladder Hypertrophy and Improves Bladder Function in Murine Model of Partial Bladder Outlet Obstruction

作者：Nao Iguchi^a ; Anna P. Malykhina^a ; Duncan T. Wilcox^a ; ^b ; ^{Duncan.Wilcox@childrenscolorado.org" class="auth_mail" title="E-mail the corresponding author}

关键词：urinary bladder neck obstruction ; anoxia ; 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin ; hypoxia-inducible factor 1 ; muscle ; smooth

刊名：The Journal of Urology

出版年：2016

4.The role of the NADPH oxidase derived brain oxidative stress in the cocaine-related death associated with excited delirium: A literature review

作者：Stefania Schiavone^a ; ^{stefania.schiavone@unifg.it" class="auth_mail" title="E-mail the corresponding author} ; Margherita Neri^a ; Emanuela Mhillaj^b ; Cristoforo Pomara^a ; Luigia Trabace^a ; ¹ ; Emanuela Turillazzi^a ; ¹

关键词：ExDS ; Excited delirium syndrome ; NADPH ; Nicotinamide adenine dinucleotide phosphate ; ROS ; Reactive Oxygen Species ; GABA ; Gamma-AminoButyric Acid ; HSP ; Heat Shock Protein ; 17-DMAG ; 17-Dimethylaminoethylamino-17-demethoxygeldanamycin ; NF-kB ; Nuclear factor kappa-light-chain-enhancer of activated B cells ; GSH ; Glutathione ; MDMA ; 3 ; 4-methylenedioxy-methamphetamine ; MAP kinase ; Mitogen-activated protein kinase ; ERK ; Extracellular signal-regulated kinases ; i-NOS ; inducible nitric oxide synthase ; Bcl-2

刊名：Toxicology Letters

出版年：2016

5.Targeting the heat shock response in combination with radiotherapy: Sensitizing cancer cells to irradiation-induced cell death and heating up their immunogenicity

作者：Kirsten Lauber ; ^{kirsten.lauber@med.uni-muenchen.de" class="auth_mail" title="E-mail the corresponding author} ; Nikko Brix ; Anne Ernst ; Roman Hennel ; Julia Krombach ; Heike Anders ; Claus Belka

关键词：17-AAG ; 17-(Allylamino)-17-demethoxygeldanamycin ; 17-DMAG ; 17-Dimethylaminoethylamino-17-demethoxygeldanamycin ; AKT ; v-akt murine thymoma viral oncogene homolog ; APC ; antigen presenting cell ; ATM ; Ataxia telangiectasia mutated ; ATR ; Ataxia telangiectasia and RAD3 related ; BAX ; BCL-2 associated X protein ; BCL-2 ; B cell lymphoma 2 ; BRCA1/2 ; breast cancer 1/2 ; CDK ; cyclin-dependent kinase ; CDKI ; cyclin-dependent kinase inhibitor ; cGAS ; cyclic GMP-AMP synthase ; CTLA-4 ; cytotoxic T lymphocyte-associa

刊名：Cancer Letters

出版年：2015

6.PU-H71: An improvement on nature's solutions to oncogenic Hsp90 addiction

作者：Matthew Trendowski^a ; ^b ; ^{mat2065@med.cornell.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Geldanamycin ; Radicicol ; 17-AAG (17-N-allylamino-17-demethoxygeldanamycin/tanespimycin) ; 17-DMAG (17-desmethoxy-17-N ; N-dimethylaminoethylaminogeldanamycin/alvespimycin) ; IPI-504 (retaspimycin) ; STA-9090 (ganetespib) ; PU3 (9-butyl-8(34 ; 5-trimethoxy-benzyl)-9H-purin-6-ylamine) ; BIIB021 (6-chloro-9-((4-methoxy-3 ; 5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amine) ; PU-H71 (8-[(6-iodo-1 ; 3-benzodioxol-5-yl)sulfanyl]-9-[3-(propan-2-ylamino)propyl]purin-6-amine)

刊名：Pharmacological Research

出版年：2015

7.Destabilization of PDK1 by Hsp90 inactivation suppresses hepatitis C virus replication through inhibition of PRK2-mediated viral RNA polymerase phosphorylation

作者：Mi-Gyeong Kim ; Jae-Su Moon ; Eun-Jung Kim ; Seung-Hoon Lee ; Jong-Won Oh ; ^{jwoh@yonsei.ac.kr}

关键词：Hsp90 ; heat shock protein 90 ; HCV ; hepatitis C virus ; RdRp ; RNA-dependent RNA polymerase ; 17-DMAG ; 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin ; PDK1 ; phosphoinositide-dependent kinase-1 ; PRK2 ; protein kinase C-related kinase 2

刊名：Biochemical and Biophysical Research Communications

出版年：2012

8.The anti-proliferative effect of heat shock protein 90 inhibitor, 17-DMAG, on non-small-cell lung cancers being resistant to EGFR tyrosine kinase inhibitor

作者：Naruyuki Kobayashi^a ; Shinichi Toyooka^a ; ^{toyooka@md.okayama-u.ac.jp} ; Junichi Soh^a ; Hiromasa Yamamoto^a ; Hideaki Dote^a ; Kensuke Kawasaki^a ; Hiroki Otani^a ; Takafumi Kubo^a ; Masaru Jida^a ; Tsuyoshi Ueno^a ; Midori Ando^a ; Atsuko Ogino^b ; Katsuyuki Kiura^b ; Shinichiro Miyoshi^a

关键词：Hsp90 ; Hsp90 inhibitor ; 17-DMAG ; Gefitinib ; EGFR mutation ; EGFR-TKI ; Acquired resistance

刊名：Lung Cancer

出版年：2012

9.Phase I trial of 17-dimethylaminoethylamino-17-demethoxygeldanamycin (17-DMAG), a heat shock protein inhibitor, administered twice weekly in patients with advanced malignancies

作者：Shivaani Kummar ; Martin E. Gutierrez ; Erin R. Gardner ; Xiaohong Chen ; William D. Figg ; Maria Zajac-Kaye ; Min Chen ; Seth M. Steinberg ; Christine A. Muir ; Mary Ann Yancey ; Yvonne R. Horneffer ; Lamin Juw

关键词：Clinical trial ; Phase I ; 17-DMAG ; Hsp90

刊名：European Journal of Cancer

出版年：2010

10.Autophagy inhibition sensitizes multiple myeloma cells to 17-dimethylaminoethylamino-17-demethoxygeldanamycin-induced apoptosis

作者：Carmen Palacios ; Rosa Martí ; n-Pé ; rez ; Ana Isabel Ló ; pez-Pé ; rez ; Atanasio P ; iella ; Abelardo Ló ; pez-Rivas

关键词：3-MA ; 17DMAG ; Apoptosis ; Autophagy ; Multiple myeloma

刊名：Leukemia Research

出版年：2010

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