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在“
Elsevier电子期刊
”中,
命中:
4
条,耗时:0.0149979 秒
1.
Exploring the
2
- and
5
-positions of the pyrazolo[4,
3
-d]pyrimidin-7-amino scaffold to target human A
1
and A
2
A
adenosine receptors
作者:
Lucia Squarcialupi
a
;
Matteo Falsini
a
;
Daniela Catarzi
a
;
Flavia Varano
a
;
Marco Betti
a
;
Katia Varani
b
;
Fabrizio Vincenzi
b
;
Diego Dal Ben
c
;
Catia Lambertucci
c
;
Rosaria Volpini
c
;
Vittoria Colotta
a
;
vittoria.colotta@unifi.it" class="auth_mail" title="E-mail the corresponding author
关键词:
AR
;
adenosine receptor
;
PD
;
Parkinson&rsquo
;
s disease
;
CCPA
;
2
-
chloro
-N(6)-cyclopentyladenosine
;
NECA
;
5
&
prime
;
-(N-ethyl-carboxamido)adenosine
;
cAMP
;
cyclic adenosine monophosphate
;
Cl-IB-MECA
;
2
-
chloro
-
N6
-(
3
-
iodobenzyl
)
5
&
prime
;
-(N-methylcarbamoyl)adenosine
;
DPCPX
;
8-cyclopentyl-1
;
3
-dipropyl-xanthine
;
ZM
2
41
3
8
5
;
4-(
2
-[7-amino-
2
-(
2
-furyl)[1
2 ;
4]-triazolo[
2
;
3
-a][1
3 ;
5
]triazin-
5
-ylamino]ethyl)phenol
;
I-AB-MECA
;
N6
-(4-amino-
3
-
iodobenzyl
)-
5
&
prime
;
-(N-methylcarbamoyl)adenosine
;
EL
2
;
second extracellula
刊名:Bioorganic & Medicinal Chemistry
出版年:
2
016
2.
Equilibrium and kinetic selectivity profiling on the human adenosine receptors
作者:
Dong Guo
1
;
Gabrielle S. Dijksteel
;
Tirsa van Duijl
;
Maxime Heezen
;
Laura H. Heitman
;
Adriaan P. IJzerman
;
ijzerman@lacdr.leidenuniv.nl" class="auth_mail" title="E-mail the corresponding author
关键词:
ARs
;
adenosine receptors
;
CGS1
5
94
3
;
9-
chloro
-
2
-(
2
-furanyl)-[1
2 ;
4]triazolo [1
;
5
-c]quinazolin-
5
-amine
;
CHAPS
;
3
-[(
3
-cholamidopropyl)dimethylammonio]-1-propanesulfonate
;
CPA
;
N6
-cyclopentyladenosine
;
DPCPX
;
1
;
3
-dipropyl-8-cyclopentylxanthine
;
IB-MECA
;
N6
-(
3
-
Iodobenzyl
)adenosine-
5
&
prime
;
-N-methyluronamide
;
GPCR
;
G protein-coupled receptor
;
k1
;
the association rate constant of the radioligand
;
k
2
;
the dissociation rate constant of the radioligand
;
k
3
;
the association rate constant of the unlabeled l
刊名:Biochemical Pharmacology
出版年:
2
016
3.
Thio-Cl-IB-MECA, a novel A
3
adenosine receptor agonist, suppresses angiogenesis by regulating PI
3
K/AKT/mTOR and ERK signaling in endothelial cells
作者:
Gi Dae Kim
;
Jedo Oh
;
Lak Shin Jeong
;
Sang Kook Lee
关键词:
A
3
AR
;
A
3
adenosine receptor
;
thio-Cl-IB-MECA
;
2
-
chloro
-
N6
-(
3
-
iodobenzyl
)-4&
prime
;
-thioadenosine-
5
&
prime
;
-N-methyluronamide
;
HUVECs
;
human umbilical vein endothelial cells
;
mES
;
mouse embryonic stem
;
EB
;
embryoid body
;
PECAM
;
platelet/endothelial cell adhe
刊名:Biochemical and Biophysical Research Communications
出版年:
2
01
3
4.
Adenosine A
3
receptor-induced proliferation of primary human coronary smooth muscle cells involving the induction of early growth response genes
作者:
A.V. Hinze
;
P. Mayer
;
A. Harst
;
I. von K¨¹gelgen
关键词:
CCPA
;
2
-
chloro
-
N6
-cyclopentyladenosine
;
2
-
chloro
-IB-MECA
;
2
-
chloro
-
N6
-(
3
-
iodobenzyl
)adenosine-
5
&
prime
;
-N-methylcarboxamide
;
DPCPX
;
8-cyclopentyl-1
;
3
-dipropylxanthine
;
EGR
;
early growth response protein
;
MAPK
;
mitogen-activated protein kinase
;
MRS1
523
;
3
-p
刊名:Journal of Molecular and Cellular Cardiology
出版年:
2
01
2
1
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