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1.Human 15-LOX-1 active site mutations alter inhibitor binding and decrease potency

作者：Michelle Armstrong^a ; Christopher van Hoorebeke^a ; Thomas Horn^a ; ^&dagger ; ; Joshua Deschamps^a ; J. Cody Freedman^a ; Chakrapani Kalyanaraman^b ; Matthew P. Jacobson^b ; Theodore Holman^a ; ^{holman@ucsc.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：LOX ; lipoxygenase ; h15-LOX-1 ; human reticulocyte 15-lipoxygenase-1 ; tPA ; tissue plasminogen activator ; FDA ; Food and Drug Administration ; s15-LOX-1 ; soybean 15-lipoxygenase-1 ; r15-LOX ; rabbit reticulocyte 15-LOX ; AA ; arachidonic acid ; 12-HpETE ; 12-hydroperoxyeicosatetraenoic acid ; LA ; linoleic acid ; 9R-HpODE ; 9-(R)-hydroperoxyoctadecadienoic acid ; 13-HpODE ; 13-(S)-hydroperoxyoctadecadienoic acid ; 15-HpETE ; 15-hydroperoxyeicosatetraenoic acid ; ICP-MS ; inductively coupled plasma mass spectrometer

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

2.Replacement of two amino acids of 9R-dioxygenase-allene oxide synthase of Aspergillus niger inverts the chirality of the hydroperoxide and the allene oxide

作者：Linda Sooman^a ; Anneli Wennman^a ; Mats Hamberg^b ; Inga Hoffmann^a ; Ernst H. Oliw^a ; ^{Ernst.Oliw@farmbio.uu.se" class="auth_mail" title="E-mail the corresponding author}

关键词：AOS ; allene oxide synthase(s) ; CP ; chiral phase ; COX ; cyclooxygenase(s) ; CYP ; cytochrome P450 ; DiHODE ; dihydroxyoctadecadienoic acid ; DOX ; dioxygenase(s) ; EAS ; epoxyalcohol synthase ; 9(10)-EODE ; 9(10)-epoxy-10 ; 12(Z)-octadecadienoic acid ; 9 ; 10-DiHOME ; 9 ; 10-dihydroxy-12(Z)-octadecamonoenoic acid ; 9 ; 14-DiHODE ; 9 ; 14-dihydroxy-10(E) ; 12(E)-octadecadienoic acid ; 9-HPODE ; 9-hydroperoxy-10(E) ; 12(Z)-octadecadienoic acid ; HPOME ; hydroperoxyoctadecamonoenoic acid ; HPOTrE ; hydroperoxyoctadecatrienoic acid ; L

刊名：Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids

出版年：2016

3.Linoleate 9R-dioxygenase and allene oxide synthase activities of Aspergillus terreus

作者：Fredrik Jernerén ; Inga Hoffmann ; Ernst H. Oliw

关键词：Catalase ; Cytochrome P450 ; 9R-HpODE ; Heme peroxidase ; Jasmonic acid ; Oxygenation mechanism ; Potato stolons

刊名：Archives of Biochemistry and Biophysics

出版年：2010

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