搜索页_ Aβ aggregation

设为首页

收藏本站

网站地图 | English | 公务邮箱

About the library

Background
History
Leadership
Organization

Readers' Guide

Opening Hours
Collections
Help Via Email

Publications

Electronic Information Resources

常用资源

在“Elsevier电子期刊”中，命中：113条，耗时：小于0.01 秒

在所有数据库中总计命中：1,668条

1.Dual inhibition of BACE1 and Aβ aggregation by β-ecdysone: Application of a phytoecdysteroid scaffold in Alzheimer’s disease therapeutics

作者：Sandipan Chakraborty¹ ; ^{sandipanchakraborty.13@gmail.com} ; Soumalee Basu ; ^{soumalee@gmail.com}

关键词：AD therapeutics ; BACE1 ; Aβ aggregation ; Steady-state and time-resolved fluorescence ; Molecular modeling ; AFM

刊名：International Journal of Biological Macromolecules

出版年：2017

2.Synthesis and biological evaluation of deferiprone-resveratrol hybrids as antioxidants, Aβ_1-42 aggregation inhibitors and metal-chelating agents for Alzheimer's disease

作者：Ping Xu^a ; Minkui Zhang^b ; Rong Sheng^b ; ^{shengr@zju.edu.cn} ; Yongmin Ma^a ; ^{yongmin.ma@zcmu.edu.cn}

关键词：Resveratrol derivatives ; 3-hydroxypyridin-4-one ; Beta amyloid aggregation ; Antioxidant ; Metal chelator

刊名：European Journal of Medicinal Chemistry

出版年：2017

3.Modulating amyloid-β aggregation: The effects of peptoid side chain placement and chirality

作者：J. Phillip Turner^a ; Shelby E. Chastain^b ; Dongwon Park^a ; Melissa A. Moss^b ; ^c ; Shannon L. Servoss^a ; ^{sservoss@uark.edu}

关键词：AD ; Alzheimer&rsquo ; s disease ; Aβ ; amyloid-β protein ; Aβ40 ; amyloid-β 1&ndash ; 40 ; Aβ42 ; amyloid-β 1&ndash ; 42 ; HD ; Huntington&rsquo ; s disease ; ThT ; thioflavin T ; DMF ; dimethylformamide ; TFA ; trifluoroacetic acid ; HPLC ; high performance liquid chromatography ; TEM ; transmission electron microscopy ; DMSO ; dimethyl sulfoxide

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

4.DL-3-n-butylphthalide-Edaravone hybrids as novel dual inhibitors of amyloid-β aggregation and monoamine oxidases with high antioxidant potency for Alzheimer’s therapy

作者：Xiaoming Qiang^a ; Yan Li^a ; Xia Yang^a ; Li Luo^a ; Rui Xu^a ; Yunxiaozhu Zheng^a ; Zhongcheng Cao^a ; Zhenghuai Tan^b ; ^{tanzhh616@163.com} ; Yong Deng^a ; ^{dengyong@scu.edu.cn}

关键词：Alzheimer&rsquo ; s disease ; DL-NBP-Edaravone hybrids ; Aβ aggregation inhibitors ; MAO inhibitors ; Antioxidant

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

5.Design, synthesis and biological evaluation of new phthalimide and saccharin derivatives with alicyclic amines targeting cholinesterases, beta-secretase and amyloid beta aggregation

作者：Dawid Panek^a ; ¹ ; Anna Więckowska^a ; ¹ ; Tomasz Wichur^a ; Marek Bajda^a ; Justyna Godyń^a ; Jakub Jończyk^a ; Kamil Mika^a ; Jana Janockova^b ; Ondrej Soukup^b ; Damijan Knez^c ; Jan Korabecny^b ; Stanislav Gobec^c ; Barbara Malawska^a ; ^{mfmalaws@cyf-kr.edu.pl}

关键词：Alzheimer's disease ; Multifunctional agents ; Acetylcholinesterase inhibitors ; BACE1 inhibitors ; Aβ aggregation ; Molecular docking

刊名：European Journal of Medicinal Chemistry

出版年：2017

6.Insights into the aggregation mechanism of Aβ(25-40)

作者：Jian Xiong ; Renee D. JiJi ; ^{jijir@missouri.edu}

关键词：AD ; Alzheimer's disease ; Aβ ; β-amyloid ; ThT ; thioflavin T

刊名：Biophysical Chemistry

出版年：2017

7.Synergistic effects of negatively charged hydrophobic nanoparticles and (−)-epigallocatechin-3-gallate on inhibiting amyloid β-protein aggregation

作者：Hongchen Liu ; Linling Yu ; Xiaoyan Dong ; Yan Sun ; ^{ysun@tju.edu.cn}

关键词：Polymeric nanoparticle ; (&minus ; )-Epigallocatechin-3-gallate ; Amyloid β-protein ; Aggregation ; Inhibition

刊名：Journal of Colloid and Interface Science

出版年：2017

8.Design, synthesis and biological evaluation of 4′-aminochalcone-rivastigmine hybrids as multifunctional agents for the treatment of Alzheimer's disease

作者：Ganyuan Xiao^a ; Yan Li^a ; Xiaoming Qiang^a ; Rui Xu^a ; Yunxiaozhu Zheng^a ; Zhongcheng Cao^a ; Li Luo^a ; Xia Yang^a ; Zhipei Sang^b ; Fu Su^a ; ^{sufu@scu.edu.cn} ; Yong Deng^a ; ^{dengyong@scu.edu.cn}

关键词：Alzheimer&rsquo ; s disease ; Chalcone carbamate derivatives ; Multifunctional agents ; Acetylcholinesterase inhibitors ; Aβ aggregation inhibitors ; Monoamine oxidase B inhibitors

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

9.Computational approach for the assessment of inhibitory potency against beta-amyloid aggregation

作者：Marek Bajda^a ; ^b ; ^{marek.bajda@uj.edu.pl} ; Sławomir Filipek^b

关键词：Beta-amyloid ; Aggregation ; Inhibitors ; Molecular dynamics ; Simulations

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

10.Aurone Mannich base derivatives as promising multifunctional agents with acetylcholinesterase inhibition, anti-β-amyloid aggragation and neuroprotective properties for the treatment of Alzheimer's disease

作者：Yan Li^a ; Xiaoming Qiang^a ; Li Luo^a ; Xia Yang^a ; Ganyuan Xiao^a ; Qi Liu^b ; Jiachen Ai^b ; Zhenghuai Tan^b ; ^{tanzhh616@163.com} ; Yong Deng^a ; ^{dengyong@scu.edu.cn}

关键词：Alzheimer's disease ; Aurone Mannich base derivatives ; Acetylcholinesterase inhibitors ; Aβ aggregation inhibitors ; Multifunctional agents

刊名：European Journal of Medicinal Chemistry

出版年：2017

按检索点细分(113)

题名(11)

关键词(16)

文摘(95)

按出版年细分(113)

2017年(21)

2016年(81)

2015年(10)

2011年(1)