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在“Elsevier电子期刊”中，命中：342条，耗时：0.0119994 秒

在所有数据库中总计命中：945条

1.Novel reversible methionine aminopeptidase-2 (MetAP-2) inhibitors based on purine and related bicyclic templates

作者：Timo Heinrich^a ; ^{timo.heinrich@merckgroup.com} ; Hans-Peter Buchstaller^a ; Bertram Cezanne^b ; Felix Rohdich^c ; Jö ; rg Bomke^a ; Manja Friese-Hamim^d ; Mireille Krier^a ; Thorsten Knö ; chel^e ; Djordje Musil^a ; Birgitta Leuthner^a ; Frank Zenke^f

关键词：MetAP2 ; Methionine aminopeptidase 2 ; Metalloprotease ; Purine

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

2.New and old roles of the peripheral and brain renin-angiotensin-aldosterone system (RAAS): Focus on cardiovascular and neurological diseases

作者：A Mascolo^a ; ^{annamaria.mascolo@unina2.it} ; & M Sessa^a ; C Scavone^a ; A De Angelis^a ; C Vitale^b ; L Berrino^a ; F Rossi^a ; G Rosano^b ; ^c ; A Capuano^a

关键词：Pharmacology ; Angiotensin ; Renin&ndash ; angiotensin&ndash ; aldosterone system ; Heart failure ; Coronary artery disease ; Neurological diseases

刊名：International Journal of Cardiology

出版年：2017

3.Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions

作者：Nyssa Drinkwater^a ; ^b ; ¹ ; Natalie B. Vinh^c ; ¹ ; Shailesh N. Mistry^c ; ¹ ; ³ ; Rebecca S. Bamert^a ; ^b ; Chiara Ruggeri^g ; John P. Holleran^f ; Sasdekumar Loganathan^f ; Alessandro Paiardini^e ; Susan A. Charman^d ; Andrew K. Powell^d ; Vicky M. Avery^f ; Sheena McGowan^a ; ^b ; ² ; ^{Sheena.McGowan@monash.edu" class="auth_mail" title="E-mail the corresponding author} ; Peter J. Scammells^c ; ² ; ^{Peter.Scammells@monash.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Plasmodium falciparum ; Malaria ; Aminopeptidase inhibitors ; Hydroxamic acid ; Zinc-binding group

刊名：European Journal of Medicinal Chemistry

出版年：2016

4.Novel leucine ureido derivatives as aminopeptidase N inhibitors. Design, synthesis and activity evaluation

作者：Chunhua Ma^a ; ^b ; Jiangying Cao^b ; Xuewu Liang^b ; Yongxue Huang^b ; Ping Wu^a ; Yingxia Li^a ; Wenfang Xu^b ; Yingjie Zhang^b ; ^{zhangyingjie@sdu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：Aminopeptidase N ; Inhibitors ; Leucine ureido derivatives ; Synthesis

刊名：European Journal of Medicinal Chemistry

出版年：2016

5.Discovery of potent and selective inhibitors of human aminopeptidases ERAP1 and ERAP2 by screening libraries of phosphorus-containing amino acid and dipeptide analogues

作者：Ewelina Węglarz-Tomczak^a ; Stamatia Vassiliou^b ; Artur Mucha^a ; ^{artur.mucha@pwr.edu.pl" class="auth_mail" title="E-mail the corresponding author}

关键词：Metalloaminopeptidases ; Antigenic peptide processing ; Organophosphorus inhibitors ; SAR studies

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

6.Does the inclusion of protease inhibitors in the insemination extender affect rabbit reproductive performance?

作者：L. Casares-Crespo^a ; J.S. Vicente^b ; A.M. Talavá ; n^b ; M.P. Viudes-de-Castro^a ; ^{viudes_mar@gva.es" class="auth_mail" title="E-mail the corresponding author}

关键词：Rabbit ; Aminopeptidase activity ; Protease inhibitor ; Seminal quality ; Reproductive performance

刊名：Theriogenology

出版年：2016

7.Discovery of potent, reversible MetAP2 inhibitors via fragment based drug discovery and structure based drug design—Part 2

作者：Christopher McBride^a ; ; Zacharia Cheruvallath^a ; Mallareddy Komandla^a ; Mingnam Tang^a ; Pamela Farrell^b ; J. David Lawson^c ; Darin Vanderpool^b ; Yiqin Wu^b ; Douglas R. Dougan^d ; Artur Plonowski^b ; Corine Holub^b ; Chris Larson^b

关键词：Methionine aminopeptidase-2 ; MetAP2 ; Metalloprotease ; Fragment-based drug discovery ; FBDD ; Structure-based drug design ; SBDD ; Pyrazolo[4 ; 3-b]indoles

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

8.Discovery of potent, reversible MetAP2 inhibitors via fragment based drug discovery and structure based drug design—Part 1

作者：Zacharia Cheruvallath^a ; ; Mingnam Tang^a ; Christopher McBride^a ; Mallareddy Komandla^a ; Joanne Miura^a ; Thu Ton-Nu^a ; Phil Erikson^a ; Jun Feng^a ; Pamela Farrell^b ; J. David Lawson^c ; Darin Vanderpool^b ; Yiqin Wu^b ; Douglas R. Dougan^d ; Artur Plonowski^b ; Corine Holub^b ; Chris Larson^b

关键词：FBDD ; Fragment-based drug discovery ; MetAP2 ; Methionine aminopeptidase 2 ; Metalloprotease ; Indazole

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

9.A structural insight into the P1S1 binding mode of diaminoethylphosphonic and phosphinic acids, selective inhibitors of alanine aminopeptidases

作者：Ewelina Węglarz-Tomczak^a ; Łukasz Berlicki^a ; Małgorzata Pawełczak^b ; Bogusław Nocek^c ; Andrzej Joachimiak^c ; Artur Mucha^a ; ^{artur.mucha@pwr.edu.pl" class="auth_mail" title="E-mail the corresponding author}

关键词：Metalloaminopeptidases ; Aminopeptidase N ; Neisseria meningitidis ; Phosphonic and phosphinic acids ; APN-inhibitor complex structures ; S1 binding mode

刊名：European Journal of Medicinal Chemistry

出版年：2016

10.Forebrain neurone-specific deletion of insulin-regulated aminopeptidase causes age related deficits in memory

作者：Holly R. Yeatman ; PhD^a ; ¹ ; Anthony L. Albiston ; PhD^b ; Peta Burns ; BSc^c ; Siew Yeen Chai ; PhD^c ; ^{siew.chai@monash.edu}

关键词：IRAP ; Aminopeptidase ; Memory ; Forebrain ; Angiotensin IV

刊名：Neurobiology of Learning and Memory

出版年：2016

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