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在“Elsevier电子期刊”中，命中：8条，耗时：0.0399819 秒

在所有数据库中总计命中：13条

1.A continuous and direct assay to monitor leucine-rich repeat kinase 2 activity

作者：Rafael G. Silva ; ^{rafaelguimaraes.dasilva@pfizer.com" class="auth_mail} ; Kieran F. Geoghegan ; Xiayang Qiu ; Ann Aulabaugh

关键词：Leucine-rich repeat kinase 2 ; Chelation-enhanced fluorescence ; Parkinson&rsquo ; s disease ; LRRK2 mutations ; LRRK2 kinetics

刊名：Analytical Biochemistry

出版年：1 April, 2014

2.Discovery and initial optimization of 5,5′-disubstituted aminohydantoins as potent β-secretase (BACE1) inhibitors

作者：Pawel Nowak ; Derek C. Cole ; Ann Aulabaugh ; Jonathan Bard ; Rajiv Chopra ; Rebecca Cowling ; Kristi Y. Fan ; Baihua Hu ; Steve Jacobsen ; Minakshi Jani ; Guixan Jin ; Mei-Chu Lo ; Michael S. Malamas ; Eric S. Ma

关键词：BACE1 ; Aminohydantoin ; Alzheimer’ ; s disease

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：2010

3.A fluorescent assay suitable for inhibitor screening and vanin tissue quantification

作者：Benfang H. Ruan ; Derek C. Cole ; Paul Wu ; Amira Quazi ; Karen Page ; Jill F. Wright ; Nelson Huang ; Joseph R. Stock ; Karl Nocka ; Ann Aulabaugh ; Rustem Krykbaev ; Lori J. Fitz ; Neil M. Wolfman ; Margaret L.

关键词：Vanin-1 ; Fluorescent assay ; Inflammatory disease ; HTS assay ; Lead identification ; Tissue quantification ; K_m ; Pantetheinase activity

刊名：Analytical Biochemistry

出版年：2010

4.3,4-Dihydropyrimido(1,2-a)indol-10(2H)-ones as potent non-peptidic inhibitors of caspase-3

作者：Lisa M. Havran ; Dan C. Chong ; Wayne E. Childers ; Paul J. Dollings ; Arlene Dietrich ; Boyd L. Harrison ; Vasilios Marathias ; Gregory Tawa ; Ann Aulabaugh ; Rebecca Cowling ; Bhupesh Kapoor ; Weixin Xu ; Lidia

关键词：Caspase-3 ; Stroke ; Apoptosis ; Pyrimidoindolone

刊名：Bioorganic and Medicinal Chemistry

出版年：2009

5.P2-337: Characterization of the affinity of GSI-953 for binding to gamma-secretase and comparison to benchmark gamma-secretase inhibitors

作者：Anthony F. Kreft ; Magid A. Abou-Gharbia ; Ann E. Aulabaugh ; Kevin P. Atchison ; George Diamantidis ; Boyd L. Harrison ; Warren D. Hirst ; Xinyi Huang ; Dennis M. Kubrak ; Kerri Lipinski ; Ronald L. Magolda ; Robert L. Martone ; Michael K. May ; Scott C. Mayer ; Menelas N. Pangalos ; Alex M. Porte ; Peter H. Reinh

刊名：Alzheimer's Dementia

出版年：2008

6.Development and comparison of nonradioactive in vitro kinase assays for NIMA-related kinase 2

作者：Guixian Jin ; Ann Aulabaugh ; Jennifer Pocas ; Hao Liu ; Ron Kriz and Deepak Sampath

刊名：Analytical Biochemistry

出版年：2006

7.Evaluation of fluorescence-based thermal shift assays for hit identification in drug discovery

作者：Lo ; Mei-Chu ; Aulabaugh ; Ann ; Jin ; Guixian ; Cowling ; Rebecca ; Bard ; Jonathan ; Malamas ; Michael ; et. al.

关键词：Thermal shift assay ; Ligand-binding affinity ; BACE1 ; ITC

刊名：Analytical Biochemistry

出版年：2004

8.Human Ras converting enzyme endoproteolytic specificity at the P2′ and P3′ positions of K-Ras-derived peptides

作者：Hollander ; Irwin J. ; Frommer ; Eileen ; Aulabaugh ; Ann ; Mallon ; Robert

关键词：Ftase ; Farnesyl transferase ; RCE1 ; Ras ; Endoprotease ; hRCE1 ; human Ras converting enzyme ; f ; farnesyl ; ABZ ; 2-aminobenzoyl ; aa ; amino acid ; FTase ; farnesyl transferase ; Q_L ; lysine ?-dinitrophenyl ; Q_S ; dinitrophenyl-diaminopropionic a

刊名：Biochimica et Biophysica Acta - Proteins and Proteomics

出版年：2003

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