搜索页_+Anti-Alzheimer+agent

设为首页

收藏本站

网站地图 | English | 公务邮箱

About the library

Background
History
Leadership
Organization

Readers' Guide

Opening Hours
Collections
Help Via Email

Publications

Electronic Information Resources

常用资源

在“Elsevier电子期刊”中，命中：134条，耗时：0.0659669 秒

在所有数据库中总计命中：2,101条

1.Synthesis and application of β-carbolines as novel multi-functional anti-Alzheimer’s disease agents

作者：William Horton^a ; Abha Sood^a ; Swarada Peerannawar^a ; Nandor Kugyela^a ; Aditya Kulkarni^a ; Rekha Tulsan^a ; Chris D. Tran^a ; Jessica Soule^a ; Harry LeVine III^b ; Bé ; la Tö ; rö ; k^a ; Marianna Tö ; rö ; k^a ; ^{marianna.torok@umb.edu}

关键词：Alzheimer&rsquo ; s disease ; Amyloid beta ; Cholinesterase inhibition ; Antioxidant ; β-Carbolines

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

2.N-Propargylpiperidines with naphthalene-2-carboxamide or naphthalene-2-sulfonamide moieties: Potential multifunctional anti-Alzheimer’s agents

作者：Urban Ko&scaron ; ak^a ; Damijan Knez^a ; Nicolas Coquelle^b ; Boris Brus^a ; Anja Pi&scaron ; lar^a ; Florian Nachon^c ; Xavier Brazzolotto^c ; Janko Kos^a ; Jacques-Philippe Colletier^b ; Stanislav Gobec^a ; ^{stanislav.gobec@ffa.uni-lj.si}

关键词：Multitarget-directed ligands ; Butyrylcholinesterase inhibitors ; MAO-B inhibitors ; Alzheimer&rsquo ; s disease

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

3.2,4-Disubstituted quinazolines as amyloid-β aggregation inhibitors with dual cholinesterase inhibition and antioxidant properties: Development and structure-activity relationship (SAR) studies

作者：Tarek Mohamed^a ; ^b ; Praveen P.N. Rao^a ; ^{praopera@uwaterloo.ca}

关键词：Alzheimer's disease ; Amyloid-beta ; Cholinesterase ; Quinazoline ; Molecular modeling

刊名：European Journal of Medicinal Chemistry

出版年：2017

4.New azepino[4,3-b]indole derivatives as nanomolar selective inhibitors of human butyrylcholinesterase showing protective effects against NMDA-induced neurotoxicity

作者：Modesto de Candia ; Giorgia Zaetta ; Nunzio Denora ; Domenico Tricarico ; Maria Majellaro ; Saverio Cellamare ; Cosimo D. Altomare ; ^{cosimodamiano.altomare@uniba.it}

关键词：Alzheimer's disease ; Azepino[4 ; 3-b]indole ; Butyrylcholinesterase ; N-Methyl d-aspartate receptor ; Neuroprotection

刊名：European Journal of Medicinal Chemistry

出版年：2017

5.Nicotine versus 6-hydroxy-l-nicotine against chlorisondamine induced memory impairment and oxidative stress in the rat hippocampus

作者：Lucian Hritcu ; ^{hritcu@uaic.ro} ; Radu Ionita ; Diana Elena Motei ; Cornelia Babii ; Marius Stefan ; Marius Mihasan ; ^{marius.mihasan@uaic.ro}

关键词：Arthrobacter nicotinovorans ; Nicotine ; 6-Hydroxy-l-nicotine ; Chlorisondamine ; Memory ; Oxidative stress

刊名：Biomedicine & Pharmacotherapy

出版年：2017

6.Ferulic acid-carbazole hybrid compounds: Combination of cholinesterase inhibition, antioxidant and neuroprotection as multifunctional anti-Alzheimer agents

作者：Lei Fang^a ; ^b ; Mohao Chen^a ; Zhikun Liu^a ; ^c ; Xubin Fang^a ; Shaohua Gou^a ; ^{sgou@seu.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Li Chen^c ; ^{chenliduo12@gmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Hybrid compounds ; Antioxidant ; Anti-Alzheimer ; AChE inhibitor

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

7.Design, synthesis and evaluation of 4-dimethylamine flavonoid derivatives as potential multifunctional anti-Alzheimer agents

作者：Wen Luo^a ; ¹ ; Ting Wang^a ; ¹ ; Chen Hong^a ; ^b ; Ya&ndash ; Chen Yang^a ; Ying Chen^a ; Juan Cen^a ; ^{675711997@qq.com" class="auth_mail" title="E-mail the corresponding author} ; Song&ndash ; Qiang Xie^c ; Chao&ndash ; Jie Wang^a ; ^{wcjsxq@163.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Flavonoid ; Anti-Alzheimer agent ; Cholinesterase ; Aβ aggregation ; Antioxidation

刊名：European Journal of Medicinal Chemistry

出版年：2016

8.Synthesis, pharmacological assessment, molecular modeling and in silico studies of fused tricyclic coumarin derivatives as a new family of multifunctional anti-Alzheimer agents

作者：Jeelan Basha Shaik^a ; Bhagath Kumar Palaka^b ; Mohan Penumala^a ; Kasi Viswanath Kotapati^b ; Subba Rao Devineni^c ; Siddhartha Eadlapalli^d ; M. Manidhar Darla^c ; Dinakara Rao Ampasala^b ; Ramakrishna Vadde^d ; G. Damu Amooru^a ; ^{agdamu01@gmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Alzheimer's disease ; Fused tricyclic coumarin ; Antioxidant ; Acetylcholinesterase ; Butyrylcholinesterase ; Neuroprotection ; Molecular modeling study ; ADMET

刊名：European Journal of Medicinal Chemistry

出版年：2016

9.Design and synthesis of novel anti-Alzheimer’s agents: Acridine-chromenone and quinoline-chromenone hybrids

作者：Zahra Najafi^a ; Mina Saeedi^b ; ^c ; Mohammad Mahdavi^d ; Reyhaneh Sabourian^c ; Mahnaz Khanavi^e ; Maliheh Barazandeh Tehrani^a ; Farshad Homayouni Moghadam^f ; Najmeh Edraki^g ; Elahe Karimpor-Razkenari^c ; Mohammad Sharifzadeh^h ; Alireza Foroumadiⁱ ; Abbas Shafieeⁱ ; Tahmineh Akbarzadeh^a ; ^c ; ^{akbarzad@tums.ac.ir" class="auth_mail" title="E-mail the corresponding author}

关键词：Acridine-chromenone ; Alzheimer&rsquo ; s disease ; Anti-cholinesterase ; Docking study ; Neuroprotective activity ; Quinoline-chromenone ; β-Secretase inhibitor

刊名：Bioorganic Chemistry

出版年：2016

10.Development of cyanopyridine-triazine hybrids as lead multitarget anti-Alzheimer agents

作者：Mudasir Maqbool^a ; Apra Manral^b ; Ehtesham Jameel^c ; Jitendra Kumar^a ; Vikas Saini^b ; Ashutosh Shandilya^d ; Manisha Tiwari^b ; ^{mtiwari07@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Nasimul Hoda^a ; ^{nhoda@jmi.ac.in" class="auth_mail" title="E-mail the corresponding author} ; B. Jayaram^d ; ^e ; ^f

关键词：DOHQPHWDPCNACE-UHFFFAOYSA-N

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

按检索点细分(134)

题名(14)

关键词(13)

文摘(70)

按出版年细分(134)

2027年及以后(9)

2017年(5)

2016年(15)

2015年(5)

2013年(9)

2012年(9)

2011年(8)

2010年(2)

2009年(2)

2008年(5)

2007年(17)

2006年(8)

2005年(9)

2004年(3)

2003年(1)

2002年(7)

2001年(3)

2000年(3)

2000年及以前(14)