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CNKI学位论文(7)
知网期刊论文(1)
在“
Elsevier电子期刊
”中,
命中:
17
条,耗时:小于0.01 秒
在所有数据库中总计命中:
8
条
1.
Discovery of potent and selective nonsteroidal indazolyl a
m
ide glucocorticoid receptor agonists
作者:
Ja
m
es E. Sheppeck II
;
John L. Gil
m
ore
;
Hai-Yun Xiao
;
T.G.
M
urali Dhar
;
David Nirschl
;
Arthur
M
.
Doweyko
;
Jack S. Sack
;
M
artin J. Corbett
;
M
ary F. Malley
;
Jack Z. Gougoutas
;
Lorraine
M
ckay
;
M
ark D. Cunningha
m
;
Siu
m
F. Habte
;
John H. Dodd
;
Steven G. Nadler
;
John E. So
m
erville
;
Joel C. Barrish
关键词:
GR agonist
;
Glucocortocoid receptor
;
Dissociated GR inhibitors
刊名:Bioorganic and
M
edicinal Che
m
istry Letters
出版年:2013
2.
Synthesis and structure-activity relationships of novel indazolyl glucocorticoid receptor partial agonists
作者:
John L. Gil
m
ore
;
Ja
m
es E. Sheppeck II
;
Ji
m
Wang
;
T.G.
M
urali Dhar
;
Cullen Cavallaro
;
Arthur
M
.
Doweyko
;
Lorraine
M
ckay
;
M
ark D. Cunningha
m
;
Siu
m
F. Habte
;
Steven G. Nadler
;
John H. Dodd
;
John E. So
m
erville
;
Joel C. Barrish
关键词:
Glucocortocoids
;
GR agonist
;
Dissociated
;
Selective GR agonist
刊名:Bioorganic and
M
edicinal Che
m
istry Letters
出版年:2013
3.
The identification of novel p38¦Á isofor
m
selective kinase inhibitors having an unprecedented p38¦Á binding
m
ode
作者:
Stephen T. Wrobleski
;
Shuqun Lin
;
T.G.
M
urali Dhar
;
Alaric J. Dyck
m
an
;
Tianle Li
;
Sidney Pitt
;
Rose
m
ary Zhang
;
Yi Fan
;
Arthur
M
.
Doweyko
;
John S. Tokarski
;
Kevin F. Kish
;
Susan E. Kiefer
;
John S. Sack
;
John A. Newitt
;
M
ark R. Wit
m
er
;
M
urray McKinnon
;
Joel C. Barrish
;
John H. Dodd
;
Gary L. Schieven
;
Katerina Leftheris
;
et al.
关键词:
p38
;
Kinase
;
Inhibitors
刊名:Bioorganic and
M
edicinal Che
m
istry Letters
出版年:2013
4.
Utilization of a nitrogen–sulfur nonbonding interaction in the design of new 2-a
m
inothiazol-5-yl-pyri
m
idines as p38α MAP kinase inhibitors
作者:
Shuqun Lin
;
Stephen T. Wrobleski
;
John Hynes Jr.
;
Sidney Pitt
;
Rose
m
ary Zhang
;
Yi Fan
;
Arthur
M
.
Doweyko
;
Kevin F. Kish
;
John S. Sack
;
M
ary F. Malley
;
Susan E. Kiefer
;
John A. Newitt
;
M
urray McKinnon
关键词:
p38
;
Kinase
;
Pyri
m
idines
;
TNF-α
;
IL-1β
刊名:Bioorganic and
M
edicinal Che
m
istry Letters
出版年:2010
5.
5-A
m
ino-pyrazoles as potent and selective p38α inhibitors
作者:
Jagab
;
hu Das
;
Robert V.
M
oquin
;
Alaric J. Dyck
m
an
;
Tianle Li
;
Sidney Pitt
;
Rose
m
ary Zhang
;
Ding Ren Shen
;
Ki
m
W. McIntyre
;
Kathleen Gillooly
;
Arthur
M
.
Doweyko
;
John A. Newitt
;
John S. Sack
;
Hongjian
关键词:
p38 Inhibitors
;
A
m
ino-pyrazoles
刊名:Bioorganic and
M
edicinal Che
m
istry Letters
出版年:2010
6.
Discovery of novel dihydro-9,10-ethano-anthracene carboxa
m
ides as glucocorticoid receptor
m
odulators
作者:
Bingwei V. Yang
;
Wayne Vaccaro
;
Arthur
M
.
Doweyko
;
Lidia
M
.
Doweyko
;
Tra
m
Huynh
;
David Tortolani
;
Steven G. Nadler
;
Lorraine
M
cKay
;
John So
m
erville
;
Deborah A. Holloway
;
Siu
m
Habte
;
David S. Weinstein
关键词:
Glucocorticoid receptor
m
odulators
;
Dihydro-9
;
10-ethano-anthracene-11-carboxa
m
ides
;
Dissociation
;
Transrepression
;
Transactivation
;
Anti-infla
mm
atory activity
刊名:Bioorganic and
M
edicinal Che
m
istry Letters
出版年:2009
7.
Synthesis and SAR of new pyrrolo[2,1-f][1,2,4]triazines as potent p38α
M
AP kinase inhibitors
作者:
Stephen T. Wrobleski
;
Shuqun Lin
;
John Hynes Jr.
;
Hong Wu
;
Sidney Pitt
;
Ding Ren Shen
;
Rose
m
ary Zhang
;
Kathleen
M
. Gillooly
;
David J. Shuster
;
Ki
m
W. McIntyre
;
Arthur
M
.
Doweyko
;
Kevin F. Kish
;
Jeffre
关键词:
p38
;
Kinase
;
Infla
mm
ation
;
Pyrrolotriazines
;
TNF-
mg src=""http
;
//www.sciencedirect.co
m
/scidiri
m
g/entities/204e.gif"" alt=""greek s
m
all letter alpha"" title=""greek s
m
all letter alpha"" border=""0"">
;
IL-1
刊名:Bioorganic and
M
edicinal Che
m
istry Letters
出版年:2008
8.
Pyrazolo-pyri
m
idines: A novel heterocyclic scaffold for potent and selective p38α inhibitors
作者:
Jagab
;
hu Das
;
Robert V.
M
oquin
;
Sidney Pitt
;
Rose
m
ary Zhang
;
Ding Ren Shen
;
Ki
m
W. McIntyre
;
Kathleen Gillooly
;
Arthur
M
.
Doweyko
;
John S. Sack
;
Hongjian Zhang
;
Susan E. Kiefer
;
Kevin Kish
;
M
urray McK
关键词:
p38
mg src=""http
;
//www.sciencedirect.co
m
/scidiri
m
g/entities/204e.gif"" alt=""greek s
m
all letter alpha"" title=""greek s
m
all letter alpha"" border=""0""> inhibitors
;
Pyrazolo-pyri
m
idines
刊名:Bioorganic and
M
edicinal Che
m
istry Letters
出版年:2008
9.
Benzothiazole based inhibitors of p38α
M
AP kinase
作者:
Chunjian Liu
;
Ja
m
es Lin
;
Sidney Pitt
;
Rose
m
ary F. Zhang
;
John S. Sack
;
Susan E. Kiefer
;
Kevin Kish
;
Arthur
M
.
Doweyko
;
Hongjian Zhang
;
Punit H.
M
arathe
;
Ja
m
es Trzaskos
;
M
urray Mckinnon
;
John H. Dodd
关键词:
Inhibitors of p38
mg src=""http
;
//www.sciencedirect.co
m
/scidiri
m
g/entities/204e.gif"" alt=""greek s
m
all letter alpha"" title=""greek s
m
all letter alpha"" border=""0""> MAP kinase
;
Benzothiazoles
;
Vicinal phenyl
;
benzo[
d
]thiazol-6-yl oxazoles
;
Vicinal phen
刊名:Bioorganic and
M
edicinal Che
m
istry Letters
出版年:2008
10.
Esti
m
ation of hERG inhibition of drug candidates using
m
ultivariate property and phar
m
acophore SAR
作者:
Stephen R. Johnson
;
Hongwen Yue
;
M
ary Lee Conder
;
Hong Shi
;
Arthur
M
.
Doweyko
;
John Lloyd
;
Paul Levesque
关键词:
hERG
;
Novelty detection
;
Phar
m
acophore
m
odel
;
Prolonged QTc
;
QSAR
;
In silico
刊名:Bioorganic and
M
edicinal Che
m
istry
出版年:2007
1
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