设为首页
收藏本站
网站地图
|
English
|
公务邮箱
About the library
Background
History
Leadership
Organization
Readers' Guide
Opening Hours
Collections
Help Via Email
Publications
Electronic Information Resources
常用资源
电子图书
期刊论文
学位会议
外文资源
特色专题
内部出版物
在“
Elsevier电子期刊
”中,
命中:
8
条,耗时:小于0.01 秒
1.
Rational design of an AKR1C3-resistant analog of PR-104 for enzyme-prodrug therapy
作者:
Alexandra M. Mowday
a
;
Amir
Ashoorzadeh
a
;
Elsie M. Williams
b
;
1
;
Janine N. Copp
b
;
2
;
Shevan Silva
a
;
Matthew R. Bull
a
;
Maria R. Abbattista
a
;
Robert F. Anderson
a
;
c
;
Jack U. Flanagan
a
;
c
;
Christopher P. Guise
a
;
c
;
David F. Ackerley
b
;
c
;
Jeff B. Smaill
a
;
c
;
Adam V. Patterson
a
;
c
;
a.patterson@auckland.ac.nz" class="auth_mail" title="E-mail the corresponding author
关键词:
PR-104 (PubChem CID
;
11455973)
;
PR-104A (PubChem CID
;
9848786)
;
SN34037 (PubChem CID
;
73671441)
;
SN34507 (PubChem CID
;
90043967)
;
SN35539 (PubChem CID
;
90043246)
刊名:Biochemical Pharmacology
出版年:2016
2.
Creation and screening of a multi-family bacterial oxidoreductase library to discover novel nitroreductases that efficiently activate the bioreductive prodrugs CB1954 and PR-104A
作者:
Gareth A. Prosser
a
;
Janine N. Copp
a
;
Alexandra M. Mowday
b
;
Christopher P. Guise
b
;
Sophie P. Syddall
b
;
Elsie M. Williams
a
;
Claire N. Horvat
a
;
Pearl M. Swe
a
;
Amir
Ashoorzadeh
b
;
c
;
William A. Denny
b
;
c
;
Jeff B. Smaill
b
;
c
;
Adam V. Patterson
b
;
c
;
David F. Ackerley
a
;
c
;
d
;
david.ackerley@vuw.ac.nz
关键词:
CB1954
;
PR-104
;
Nitroreductase
;
Gene therapy
;
Nitroaromatic prodrug
;
SOS chromotest
刊名:Biochemical Pharmacology
出版年:2013
3.
Synthesis of substituted 5-bromomethyl-4-nitroimidazoles and use for the preparation of the hypoxia-selective multikinase inhibitor SN29966
作者:
Guo-Liang Lu
;
Amir
Ashoorzadeh
;
Robert F. Anderson
;
Adam V. Patterson
;
Jeff B. Smaill
关键词:
4-Nitroimidazole
;
Nitroarylmethyl quaternary ammonium salt
;
Hypoxia-selective multikinase inhibitor
;
SN29966
刊名:Tetrahedron
出版年:2013
4.
The effect of sulfonate leaving groups on the hypoxia-selective toxicity of nitro analogs of the duocarmycins
作者:
Amir
Ashoorzadeh
a
;
Graham J. Atwell
a
;
Frederik B. Pruijn
a
;
William R. Wilson
a
;
Moana Tercel
a
;
William A. Denny
;
a
;
b.denny@auckland.ac.nz"" rel=""nofollow
;
Ralph J. Stevenson
a
关键词:
Cyclopropylindoline
;
Hypoxic selectivity
;
Prodrug
;
Sulfonate leaving group
;
DNA minor groove alkylator
;
Antitumor
;
Neutral side chain
刊名:Bioorganic and Medicinal Chemistry
出版年:2011
5.
The effect of a bromide leaving group on the properties of nitro analogs of the duocarmycins as hypoxia-activated prodrugs and phosphate pre-prodrugs for antitumor therapy
作者:
Ralph J.
;
Stevenson
;
;
;
r.stevenson@auckland.ac.nz
;
William A.
;
Denny
;
Amir
;
Ashoorzadeh
;
Frederik B.
;
Pruijn
;
Wouter F.
;
van Leeuwen
;
Moana
;
Tercel
关键词:
Duocarmycins
;
Hypoxic selectivity
;
Phosphate pre-prodrug
;
Prodrug
;
Bromide leaving group
;
DNA minor groove alkylating agent
;
Antitumor
;
Basic side chain
刊名:Bioorganic and Medicinal Chemistry
出版年:2011
6.
Synthetic evaluation of an enantiopure tetrahydropyridine N
作者:
Amir
Ashoorzadeh
;
Glenn Archibald
;
Vittorio Caprio
刊名:Tetrahedron
出版年:2009
7.
305 POSTER Structure–activity relationships for lipophilic dinitrobenzamide mustards as prodrugs for Escherichia coli NfsB nitroreductase
作者:
S. Sydall
;
A.
Ashoorzadeh
;
G.A. Atwell
;
J.B. Smaill
;
W.R. Wilson
;
W.A. Denny
;
A.V. Patterson
刊名:European Journal of Cancer Supplements
出版年:2008
8.
Planar chiral (η
6
-arene)tricarbonylchromium complexes derived from mandelic acid
作者:
Woodgate
;
Paul D.
;
Ashoorzadeh
;
Amir
;
Hosseini
;
Ali
;
Rickard
;
Clifton E.F.
;
Yang
;
Lee-Kei
关键词:
Tricarbonylchromium
;
Mandelic acid
;
Planar chiral
刊名:Journal of Organometallic Chemistry
出版年:2002
1
按检索点细分(8)
作者(8)
按出版年细分(8)
2016年(1)
2013年(2)
2011年(2)
2009年(1)
2008年(1)
2002年(1)
NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via
email
.