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CNKI会议论文(5)
CNKI学位论文(11671)
CNKI期刊论文0611(6)
知网期刊论文(4692)
在“
Elsevier电子期刊
”中,
命中:
2,121
条,耗时:0.0289879 秒
在所有数据库中总计命中:
16,375
条
1.
Integrated bioinformatics, computational and experimental methods to discover novel
Raf
/extracellular-signal regulated kinase (ERK) dual
inhibitor
s against breast cancer cells
作者:
Yin Chen
a
;
1
;
Yaxin Zheng
a
;
1
;
Qinglin Jiang
a
;
b
;
1
;
Feifei Qin
a
;
Yonghui Zhang
c
;
Leilei Fu
a
;
leilei_fu@163.com
;
Gu He
a
;
hegu@scu.edu.cn
关键词:
Breast cancer
;
Raf
;
ERK
;
Bioinformatics
;
Kinase
inhibitor
刊名:European Journal of Medicinal Chemistry
出版年:2017
2.
Artesunate suppresses RANKL-induced osteoclastogenesis through inhibition of PLCγ1-Ca
2+
-NFATc1 signaling pathway and prevents ovariectomy-induced bone loss
作者:
Xiangzhou Zeng
a
;
b
;
Yueyang Zhang
a
;
Song Wang
c
;
Keng Wang
a
;
Lei Tao
a
;
Min Zou
a
;
Nana Chen
a
;
Jiake Xu
d
;
Shuwen Liu
a
;
liusw@smu.edu.cn
;
Xiaojuan Li
a
;
lixiaoj@smu.edu.cn
关键词:
Art
;
artesunate
;
RANKL
;
receptor activator of nuclear factor-κB (NF-κB) ligand
;
M-CSF
;
macrophage colony-stimulating factor
;
TRAP
;
tartrate-resistant acid phosphatase
;
T
RAF
6
;
tumor necrosis factor receptor associated factor 6
;
IκB
;
inhibitor
of nuclear factor-κB
;
NF-κB
;
nuclear factor-κB
;
NFATc1
;
nuclear factor of activated T cells c1
;
Micro-CT
;
microcomputer tomography
刊名:Biochemical Pharmacology
出版年:2017
3.
Cutaneous Adverse Events of New Anti-melanoma Therapies: Classification and Management
作者:
S.J.E. Hwang
a
;
b
;
shelley.hwang@hotmail.com
;
R. Anforth
a
;
b
;
G. Carlos
a
;
b
;
P. Fernandez-Peñ
;
as
a
;
b
关键词:
B-
Raf
inhibitor
s
;
Mitogen-activated protein kinase
inhibitor
;
Anti-Cytotoxic T-lymphocyte-associated protein 4
;
Anti-Programmed cell death-1
;
Metastatic melanoma
;
Cutaneous adverse event
刊名:Actas Dermo-Sifiliográficas (English Edition)
出版年:2017
4.
Cutaneous Adverse Events of New Anti-melanoma Therapies: Classification and Management
作者:
S.J.E. Hwang
a
;
b
;
shelley.hwang@hotmail.com
;
R. Anforth
a
;
b
;
G. Carlos
a
;
b
;
P. Fernandez-Peñ
;
as
a
;
b
关键词:
B-
Raf
inhibitor
s
;
Mitogen-activated protein kinase
inhibitor
;
Anti-Cytotoxic T-lymphocyte-associated protein 4
;
Anti-Programmed cell death-1
;
Metastatic melanoma
;
Cutaneous adverse event
刊名:Actas Dermo-Sifiliográficas
出版年:2017
5.
The GABA
B
positive allosteric modulators CGP7930 and GS39783 stimulate ERK1/2 signalling in cells lacking functional GABA
B
receptors
作者:
Maria C. Olianas
;
molianas@unica.it
;
Simona Dedoni
;
Pierluigi Onali
关键词:
CGP7930 (PubChem CID
;
5024764)
;
GS39783 (PubChem CID
;
6604928)
;
(-)-baclofen (PubChem CID
;
44602)
;
SKF97541 (PubChem CID
;
5230)
;
CGP55845 (PubChem CID
;
5311042)
;
CGP54626 (PubChem CID
;
197584)
;
phorbol 12-myristate 13 acetate (PubChem CID
;
27924)
;
Go 6850 (PubChem CID
;
2396)
;
5Z-7-oxozeaenol (PubChem CID
;
9863776)
;
GW5074 (PubChem CID
;
5924208)
刊名:European Journal of Pharmacology
出版年:2017
6.
Purinylpyridinylamino-based DFG-in/αC-helix-out B-
Raf
inhibitor
s: Applying mutant versus wild-type B-Raf selectivity indices for compound profiling
作者:
Longbin Liu
a
;
lliu@amgen.com" class="auth_mail" title="E-mail the corresponding author
;
Matthew R. Lee
b
;
&dagger
;
;
Joseph L. Kim
c
;
Douglas A. Whittington
c
;
Howard Bregman
d
;
Zihao Hua
d
;
Richard T. Lewis
d
;
Matthew W. Martin
d
;
Nobuko Nishimura
a
;
Michele Potashman
d
;
Kevin Yang
a
;
Shuyan Yi
d
;
Karina R. Vaida
d
;
Linda F. Epstein
c
;
Carol Babij
e
;
Manory Fernando
e
;
Josette Carnahan
e
;
Mark H. Norman
a
关键词:
B-
Raf
;
Inhibitor
;
DFG
;
C-helix
;
Selectivity
;
v600e
;
Wild-type
;
Sulfonamide
刊名:Bioorganic & Medicinal Chemistry
出版年:2016
7.
A
Raf
kinase
inhibitor
demonstrates antiviral activities both in vitro and in vivo against different genotypes of virulent Newcastle disease virus
作者:
Renfu Yin
a
;
yin@jlu.edu.cn" class="auth_mail" title="E-mail the corresponding author
;
Xinxin Liu
b
;
Pingze Zhang
a
;
Yanyu Chen
a
;
Guangyao Xie
a
;
Lili Ai
a
;
Cong Xue
a
;
Jing Qian
a
;
Yuhai Bi
c
;
Jianjun Chen
d
;
Yuzhang Sun
e
;
Tobias Stoeger
f
;
Zhuang Ding
a
;
dingzhuang@jlu.edu.cn" class="auth_mail" title="E-mail the corresponding author
关键词:
Newcastle disease virus
;
Raf
kinase
inhibitor
V
;
Antivirals
;
Raf
kinase
刊名:Antiviral Research
出版年:2016
8.
Inhibition of mutant Kras
G12D
-initiated murine pancreatic carcinoma growth by a dual c-
Raf
and soluble epoxide hydrolase
inhibitor
t-CUPM
作者:
Jie Liao
a
;
jie-liao@northwestern.edu" class="auth_mail" title="E-mail the corresponding author
;
Sung Hee Hwang
b
;
Haonan Li
a
;
Yihe Yang
a
;
Jun Yang
b
;
Aaron T. Wecksler
b
;
Jun-Yan Liu
b
;
Bruce D. Hammock
b
;
Guang-Yu Yang
a
;
g-yang@northwestern.edu" class="auth_mail" title="E-mail the corresponding author
关键词:
Pancreatic carcinoma
;
c-
Raf
;
Soluble epoxide hydrolase
;
Growth inhibition
刊名:Cancer Letters
出版年:2016
9.
Design and synthesis of new potent anticancer benzothiazole amides and ureas featuring pyridylamide moiety and possessing dual B-
Raf
V600E
and C-Raf kinase
inhibitor
y activities
作者:
Ash
raf
Kareem El-Damasy
a
;
b
;
c
;
Ju-Hyeon Lee
a
;
Seon Hee Seo
a
;
Nam-Chul Cho
a
;
d
;
Ae Nim Pae
a
;
b
;
Gyochang Keum
a
;
b
;
gkeum@kist.re.kr" class="auth_mail" title="E-mail the corresponding author
关键词:
Anticancer activity
;
Benzothiazole
;
Urea
;
Amide
;
Pyridylamide
;
B-
Raf
V600E
;
C-
Raf
刊名:European Journal of Medicinal Chemistry
出版年:2016
10.
Design and synthesis of N-(4-aminopyridin-2-yl)amides as B-
Raf
V600E
inhibitor
s
作者:
Xiaokai Li
a
;
&dagger
;
;
Jiayi Shen
a
;
&dagger
;
;
Li Tan
b
;
c
;
&dagger
;
;
Zhang Zhang
b
;
Donglin Gao
b
;
c
;
Jinfeng Luo
b
;
Huimin Cheng
b
;
Xiaoping Zhou
a
;
Jie Ma
a
;
Ke Ding
b
;
ding_ke@gibh.ac.cn" class="auth_mail" title="E-mail the corresponding author
;
Xiaoyun Lu
d
;
b
;
lu_xiaoyun@gibh.ac.cn" class="auth_mail" title="E-mail the corresponding author
关键词:
B-
Raf
V600E
inhibitor
;
N-(4-Aminopyridin-2-yl)amides
;
Structural modification
;
Selective
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2016
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