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在“Elsevier电子期刊”中，命中：508条，耗时：小于0.01 秒

1.From bosentan to macitentan for pulmonary arterial hypertension and adult congenital heart disease: Further improvement?

作者：Ilja M. Blok^a ; ^b ; Annelieke C.M.J. van Riel^a ; ^b ; Arie P.J. van Dijk^c ; Barbara J.M. Mulder^a ; ^b ; Berto J. Bouma^a ; ^{b.j.bouma@amc.nl}

刊名：International Journal of Cardiology

出版年：2017

2.FUTURE-2: Results from an open-label, long-term safety and tolerability extension study using the pediatric FormUlation of bosenTan in pUlmonary arterial hypeRtEnsion

作者：Rolf M.F. Berger^a ; ^{r.m.f.berger@umcg.nl" class="auth_mail" title="E-mail the corresponding author} ; Sheila G. Haworth^b ; Damien Bonnet^c ; Yves Dulac^d ; Alain Fraisse^e ; Nazzareno Galiè ; ^f ; D. Dunbar Ivy^g ; Xavier Jaï ; s^h ; Oliver Mieraⁱ ; Erika B. Rosenzweig^j ; Michela Efficace^k ; Andjela Kusic-Pajic^l ; Maurice Beghetti^m

关键词：Bosentan ; Pediatric ; Pulmonary arterial hypertension ; Safety

刊名：International Journal of Cardiology

出版年：2016

3.Effect of Bosentan on Claudication Distance and Endothelium-Dependent Vasodilation in Hispanic Patients With Peripheral Arterial Disease

作者：Joaquin De Haro ; MD ; ^{deharojoaquin@yahoo.es" class="auth_mail" title="E-mail the corresponding author} ; Silvia Bleda ; MD ; Cesar Varela ; MD ; Leticia Esparza ; MD ; Francisco Acin ; MD ; PhD ; for the Bosentan Population-Based Randomized Trial for Clinical ; Endothelial Function Assessment on Endothelin Antagonist Therapy in Patients With Intermittent Claudication (CLAU) Investigators

刊名：The American Journal of Cardiology

出版年：2016

4.Metabolism study and biological evaluation of bosentan derivatives

作者：Susan Lepri¹ ; Laura Goracci¹ ; Aurora Valeri ; Gabriele Cruciani ; ^{gabriele.cruciani@unipg.it" class="auth_mail" title="E-mail the corresponding author}

关键词：Bosentan ; Perfluorinated analogues ; Metabolic specificity ; Phase I metabolism ; HLM

刊名：European Journal of Medicinal Chemistry

出版年：2016

5.Bosentan reverses the hypoxia-induced downregulation of the bone morphogenetic protein signaling in pulmonary artery smooth muscle cells

作者：Hidekazu Maruyama^a ; ^{hide-maruyama06@ob.md.tsukuba.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Cé ; line Dewachter^a ; Satoshi Sakai^b ; Asmae Belhaj^c ; Benoit Rondelet^c ; Myriam Remmelink^d ; Jean-Luc Vachié ; ry^e ; Robert Naeije^a ; Laurence Dewachter^a

关键词：Cobalt chloride ; Hypoxia ; Endothelin ; BMPR-2 ; Pulmonary artery smooth muscle cells

刊名：Life Sciences

出版年：2016

6.From bosentan (Tracleer®) to macitentan (Opsumit®): The medicinal chemistry perspective

作者：Christoph Boss ; ^{christoph.boss@actelion.com" class="auth_mail" title="E-mail the corresponding author} ; Martin H. Bolli ; John Gatfield

关键词：G-protein-coupled receptor (GPCR) ; Endothelin ; Endothelin receptor antagonists (ERA) ; Macitentan ; Pulmonary arterial hypertension (PAH) ; Sulfamide ; Pyrimidine

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

7.Pharmacologic strategies in neonatal pulmonary hypertension other than nitric oxide

作者：Satyan Lakshminrusimha ; MD ; ^{slakshmi@buffalo.edu" class="auth_mail" title="E-mail the corresponding author} ; Bobby Mathew ; MRCP ; Corinne L. Leach ; MD ; PhD

关键词：Hypoxia ; Oxygen ; Nitric oxide ; Prostacyclin ; Sildenafil ; Bosentan ; Iloprost ; Milrinone

刊名：Seminars in Perinatology

出版年：2016

8.Both cholestatic and steatotic drugs trigger extensive alterations in the mRNA level of biliary transporters in rat hepatocytes: Application to develop new predictive biomarkers for early drug development

作者：M.Teresa Donato^a ; ^b ; ^c ; Mireia Ló ; pez-Riera^a ; José ; V. Castell^a ; ^b ; ^c ; Marí ; a J. Gó ; mez-Lechó ; n^a ; ^b ; Ramiro Jover ; PhD^a ; ^b ; ^c ; ^{ramiro.jover@uv.es}

关键词：ANIT ; α-Naphthyl isothiocyanate ; AMIK ; amikacin ; AMIO ; amiodarone hydrochloride ; AMIT ; amitriptyline ; AUC ; area under the curve ; AZAT ; azathioprine ; BA ; bile acid ; BOSE ; Bosentan ; C ; cholestatic drug ; CHLO ; chlorpromazine ; CITR ; citrate ; CYCA ; cyclosporine A ; DILI ; drug-induced liver injury ; DOXY ; doxycycline ; DMSO ; dimethyl sulfoxide ; ETHY ; ethynilestradiol ; FENO ; fenofibrate ; GLYB ; glyburide ; KETO ; ketotifen ; MAPR ; maprotiline ; METF ; metformin ; NAFLD ; non-alcoholic fatty liver disease ; NCNS ; n

刊名：Toxicology Letters

出版年：2016

9.Evidence for biased agonists and antagonists at the endothelin receptors

作者：Janet J. Maguire ^{jjm1003@medschl.cam.ac.uk" class="auth_mail" title="E-mail the corresponding author}

关键词：G protein coupled receptors ; Endothelin ; ETA ; ETB ; Biased agonism ; Biased antagonism ; β-Arrestin ; Bosentan ; Pathway selectivity ; IRL1620

刊名：Life Sciences

出版年：2016

10.Corrigendum to “FUTURE-2: Results from an open-label, long-term safety and tolerability extension study using the pediatric FormUlation of bosenTan in pUlmonary arterial hypeRtEnsion” [Int. J. Cardiol. 202 (2016) 52-58]

刊名：International Journal of Cardiology

出版年：2016

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