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内部出版物
在“
Elsevier电子期刊
”中,
命中:
508
条,耗时:小于0.01 秒
1.
Highly sensitive LC-MS/MS methods for the determination of seven human
CYP450
activities using small oral doses of probe-drugs in human
作者:
Alexia Grangeon
a
;
b
;
alexia.grangeon@umontreal.ca
;
Sophie Gravel
a
;
b
;
sophie.gravel.3@umontreal.ca
;
Fleur Gaudette
b
;
fleur.gaudette.chum@ssss.gouv.qc.ca
;
Jacques Turgeon
a
;
b
;
jacques.turgeon@umontreal.ca
;
Veronique Michaud
a
;
b
;
v.michaud@umontreal.ca
关键词:
LC&ndash
;
MS/MS
;
CYP450
probe-drug cocktail
;
Drug metabolism
;
Drug-drug interactions
;
Phenotyping
刊名:Journal of Chromatography B
出版年:2017
2.
Gut microbiome interactions with drug metabolism, efficacy, and toxicity
作者:
Ian D. Wilson
;
ianwilsonprof@gmail.com
;
Jeremy K. Nicholson
关键词:
ADMET
;
absorption
;
distribution
;
metabolism
;
excretion
;
toxicity
;
AHR
;
aryl hydrocarbon receptor
;
AUC
;
area under the curve
;
BVU
;
(E)-5-(2-bromovinyl) uracil
;
CAR
;
constitutive androstane receptor
;
cMOAT
;
Canalicular multispecific organic anion transporter 1
;
cgr
;
cardiac glycoside reductase
;
CYP450
s
;
cytochromes P450
;
DPD
;
dihydropyrimidine dehydrogenase
;
DNA
;
deoxyribonucleic acid
;
EPHXs
;
epoxide hydrolases
;
DMI&rsquo
s ;
drug-microbiome interactions
;
FDA
;
Food and Drug Administration
;
GF
;
germ
刊名:Translational Research
出版年:2017
3.
Effects of triazole fungicides on androgenic disruption and CYP3A4 enzyme activity
作者:
Xuan Lv
a
;
b
;
Liumeng Pan
a
;
Jiaying Wang
a
;
Liping Lu
a
;
b
;
Weilin Yan
a
;
c
;
Yanye Zhu
a
;
Yiwen Xu
a
;
Ming Guo
d
;
Shulin Zhuang
a
;
b
;
shulin@zju.edu.cn
关键词:
Triazole
;
Androgen receptor
;
Metabolism
;
CYP450
;
Steroid hormone
刊名:Environmental Pollution
出版年:2017
4.
Metabolic-induced cytotoxicity of diosbulbin B in CYP3A4-expressing cells
作者:
Ji-zong Jiang
a
;
Bao-hua Yang
a
;
Li-li Ji
a
;
b
;
Li Yang
a
;
b
;
Yu-Chang Mao
c
;
Zhuo-han Hu
c
;
Zheng-tao Wang
a
;
b
;
Chang-hong Wang
a
;
b
;
wchcxm@hotmail.com
关键词:
AP
;
Acetaminophen
;
CCK
;
2H&ndash
;
Tetrazolium
;
5-(2
;
4-disulfophenyl)-3-(2-methoxy&ndash
;
4-nitrophenyl)&ndash
;
2-(4-nitrophenyl)-
;
innersalt
;
sodium salt
;
CYP450
;
Cytochrome P450
;
DB
;
Diosbulbin B
;
DMEM
;
Dulbecco's Modified Eagle Medium
;
DMF
;
N
;
N-Dimethylformamide
;
DMSO
;
Dimethyl Sulphoxide
;
FBS
;
Fetal bovine serum
;
GSH
;
Glutathione
;
IS
;
Internal standard
;
KT
;
ketoconazole
;
MLM
;
Mouse liver microsomes
;
MRM
;
Multiple reaction mode
;
MS/MS
;
Mass spectrometry tandem and mass spectrometry
;
MTT
;
3-(4
;
5-Dime
刊名:Toxicology in Vitro
出版年:2017
5.
The effects of metronidazole on Cytochrome P450 Activity and Expression in rats after acute exposure to high altitude of 4300 m
作者:
Rong Wang
a
;
b
;
wangrong-69@163.com
;
Yuhuan Sun
a
;
b
;
Qiang Yin
a
;
b
;
Hua Xie
a
;
Wenbin Li
a
;
Chang Wang
a
;
b
;
Jiankui Guo
a
;
Ying Hao
a
;
b
;
Rui Tao
a
;
b
;
Zhengping Jia
a
;
b
;
关键词:
Metronidazole
;
Cytochrome P450
;
Activity and expression
;
Acute exposure
;
High altitude
刊名:Biomedicine & Pharmacotherapy
出版年:2017
6.
Stabilized and enhanced
CYP450
enzyme activity in cultured human primary hepatocytes is conferred by reprohp medium
作者:
Paul E. Cizdziel
1
;
Misturu Inamura
1
;
Rina Akihira
1
;
Zachary Yu-Ching Lin
1
;
Kenichi Tamura
1
;
Tomohisa Watanabe
1
;
Shunsuke Yoshida
1
;
Tohru Kiyono
2
刊名:Drug Metabolism and Pharmacokinetics
出版年:2017
7.
Inhibitory potential of herbal formulas on the activities of human microsomal
CYP450
S and UGTS
作者:
Seong Eun Jin
;
Hyeun-Kyoo Shin
;
Hyekyung Ha
刊名:Drug Metabolism and Pharmacokinetics
出版年:2017
8.
Cloning and expression of Sg
CYP450
-4 from Siraitia grosvenorii
作者:
Dongping Tu
a
;
Xiaojun Ma
a
;
b
;
mayixuan10@163.com" class="auth_mail" title="E-mail the corresponding author
;
Huan Zhao
a
;
Changming Mo
c
;
Qi Tang
d
;
tangqi423@sina.com" class="auth_mail" title="E-mail the corresponding author
;
Liuping Wang
e
;
Jie Huang
e
;
Limei Pan
c
关键词:
Siraitia grosvenorii
;
Auxin
;
Sg
CYP450
-4
;
CYP87A3
;
Race clone
;
Expression pattern
刊名:Acta Pharmaceutica Sinica B
出版年:2016
9.
Exploring hazards of acute exposure of Acephate in Drosophila melanogaster and search for l-ascorbic acid mediated defense in it
作者:
Prem Rajak
a
;
Moumita Dutta
b
;
Salma Khatun
b
;
Moutushi Mandi
b
;
Sumedha Roy
b
;
roysumedha@gmail.com" class="auth_mail" title="E-mail the corresponding author
关键词:
Acephate
;
Comet assay
;
Drosophila melanogaster
;
l-ascorbic acid
;
MTT assay
刊名:Journal of Hazardous Materials
出版年:2017
10.
Toxicity assessment of sodium fluoride in Drosophila melanogaster after chronic sub-lethal exposure
作者:
Moumita Dutta
a
;
Prem Rajak
b
;
Salma Khatun
a
;
Sumedha Roy
a
;
roysumedha@gmail.com" class="auth_mail" title="E-mail the corresponding author
关键词:
Drosophila melanogaster
;
Fluoride
;
Hsp 70
;
Detoxifying enzymes
;
Comet assay
;
Sodium fluoride
刊名:Chemosphere
出版年:2017
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