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CNKI学位论文(42)
知网期刊论文(10)
在“
Elsevier电子期刊
”中,
命中:
8
条,耗时:0.026019 秒
在所有数据库中总计命中:
52
条
1.
CryptoSite: Expanding the Druggable Proteome by Characterization and Prediction of
Cryptic
Binding
Sites
作者:
Peter Cimermancic
1
;
2
;
peter.cimermancic@ucsf.edu" class="auth_mail" title="E-mail the corresponding author
;
Patrick Weinkam
1
;
T. Justin Rettenmaier
3
;
4
;
Leon Bichmann
1
;
Daniel A. Keedy
1
;
Rahel A. Woldeyes
1
;
3
;
Dina Schneidman-Duhovny
1
;
Omar N. Demerdash
5
;
Julie C. Mitchell
6
;
James A. Wells
4
;
7
;
James S. Fraser
1
;
Andrej Sali
1
;
4
;
sali@salilab.org" class="auth_mail" title="E-mail the corresponding author
关键词:
cryptic
binding
sites
;
protein dynamics
;
undruggable proteins
;
machine learning
刊名:Journal of Molecular Biology
出版年:2016
2.
Application of oxime-diversification to optimize ligand interactions within a
cryptic
pocket
of the polo-like kinase 1 polo-box domain
作者:
Xue Zhi Zhao
;
David Hymel
;
Terrence R. Burke Jr.
;
burkete@helix.nih.gov" class="auth_mail" title="E-mail the corresponding author
关键词:
Plk1 polo-box domain
;
Ligand optimization
;
Oxime ligation
;
Cryptic
binding
pocket
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2016
3.
The identification, analysis and structure-based development of novel inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase
作者:
Mi-Kyung Yun
a
;
Daniel Hoagland
b
;
Gyanendra Kumar
a
;
M. Brett Waddell
a
;
Charles O. Rock
c
;
d
;
Richard E. Lee
b
;
d
;
richard.lee@stjude.org" class="auth_mail
;
Stephen W. White
a
;
d
;
stephen.white@stjude.org" class="auth_mail
关键词:
HPPK
;
6-hydroxymethyl-7
;
8-dihydropterin pyrophosphokinase
;
DHP
;
6-hydroxymethyl-7
;
8-dihydropterin
;
DHPS
;
dihydropteroate synthase
;
SPR
;
surface plasmon resonance
;
KD
;
equilibrium dissociation constant
;
IC50
;
half maximal inhibitory concentration
;
AMPCPP
;
伪
;
尾-methyleneadenosine 5&prime
;
-triphosphate
;
EcHPPK
;
Escherichia coli 6-hydroxymethyl-7
;
8-dihydropterin pyrophosphokinase
;
BME
;
2-mercaptoethanol
刊名:Bioorganic and Medicinal Chemistry
出版年:1 April, 2014
4.
Fragment screening of inhibitors for MIF tautomerase reveals a
cryptic
surface
binding
site
作者:
Larry R. McLean
;
Ying Zhang
;
Hua Li
;
Yong-Mi Choi
;
Zuoning Han
;
Roy J. Vaz
;
Yi Li
关键词:
Macrophage migration inhibitory factor
;
Tautomerase
;
Cytokine signaling
;
Fragment-based screening
;
X-ray crystallography
;
In silico docking
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2010
5.
An Allosteric Inhibitor of the Human Cdc34 Ubiquitin-Conjugating Enzyme
作者:
Derek
;
F. Ceccarelli
1
;
Xiaojing Tang
1
;
Benoit Pelletier
2
;
Stephen Orlicky
1
;
Weilin Xie
5
;
Veronique Plantevin
5
;
Dante Neculai
1
;
4
;
Yang-Chieh Chou
1
;
7
;
Abiodun Ogunjimi
1
;
Abdallah Al-Hakim
1
;
Xaralabos Varelas
1
;
Joanna Koszela
6
;
Gregory
;
A. Wasney
4
;
Masoud Vedadi
4
;
Sirano Dhe-Paganon
4
;
Sarah Cox
5
;
Shuichan Xu
5
;
Antonia Lopez-Girona
5
;
Frank Mercurio
5
;
Jeff Wrana
1
;
Daniel Durocher
1
;
Sylvain Meloche
2
;
3
;
David
;
R. Webb
5
;
dwebb@celgene.com"" rel=""nofollow
;
Mike Tyers
1
;
6
;
7
;
m.tyers@ed.ac.uk"" rel=""nofollow
;
Frank Sicheri
1
;
7
;
sicheri@lunenfeld.ca"" rel=""nofollow
刊名:Cell
出版年:2011
6.
Structural and mutational studies of organophosphorus hydrolase reveal a
cryptic
and functional allosteric-
binding
site
,
作者:
Janet K. Grimsley
;
Barbara Calamini
;
James R. Wild and Andrew D. Mesecar
关键词:
Phosphotriesterase
;
Allostery
;
Non-competitive inhibition
;
Chemical warfare agents
;
X-ray crystallography
;
Allosteric site
;
Competitive inhibition
刊名:Archives of Biochemistry and Biophysics
出版年:2005
7.
Structural Snapshot of Aberrant Antigen Presentation Linked to Autoimmunity: The Immunodominant Epitope of MBP Complexed with I-A
u
作者:
Xiao-lin He
;
Caius Radu
;
John Sidney
;
Alessandro Sette
;
E. Sally Ward and K. Christopher Garcia
刊名:Immunity
出版年:2002
8.
Identification of three aspartic acid residues essential for catalysis by the RusA holliday junction resolvase
作者:
Bolt
;
Edward L.
;
Sharples
;
Gary J.
;
Lloyd
;
Robert G.
关键词:
recombination
;
DNA repair
;
endonuclease
;
E. coli
刊名:Journal of Molecular Biology
出版年:1999
1
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