设为首页
收藏本站
网站地图
|
English
|
公务邮箱
About the library
Background
History
Leadership
Organization
Readers' Guide
Opening Hours
Collections
Help Via Email
Publications
Electronic Information Resources
常用资源
电子图书
期刊论文
学位会议
外文资源
特色专题
内部出版物
Springer电子图书(2)
CNKI会议论文(3)
CNKI学位论文(1325)
CNKI期刊论文0611(1)
知网期刊论文(895)
在“
Elsevier电子期刊
”中,
命中:
827
条,耗时:小于0.01 秒
在所有数据库中总计命中:
2,226
条
1.
Highly regioselective hydroxylation of polydatin, a resveratrol glucoside, for one-step synthesis of astringin, a piceatannol glucoside, by
P450
BM3
作者:
Thien-Kim Le
a
;
Hyun-Hee Jang
a
;
Ha Thi Huong Nguyen
a
;
Tiep Thi My Doan
a
;
Ga-Young Lee
a
;
Ki Deok Park
b
;
Taeho Ahn
c
;
Young Hee Joung
a
;
Hyung-Sik Kang
a
;
Chul-Ho Yun
a
;
chyun@jnu.ac.kr
;
chyun49@gmail.com
关键词:
NADPH
;
β-nicotinamide adenine dinucleotide phosphate (reduced form)
;
p-NP
;
p-nitrophenol
;
P450
or CYP
;
cytochromes
P450
;
TTN
;
total turnover number
;
WT
;
wild-type
刊名:Enzyme and Microbial Technology
出版年:2017
2.
Gut microbiome interactions with drug metabolism, efficacy, and toxicity
作者:
Ian D. Wilson
;
ianwilsonprof@gmail.com
;
Jeremy K. Nicholson
关键词:
ADMET
;
absorption
;
distribution
;
metabolism
;
excretion
;
toxicity
;
AHR
;
aryl hydrocarbon receptor
;
AUC
;
area under the curve
;
BVU
;
(E)-5-(2-bromovinyl) uracil
;
CAR
;
constitutive androstane receptor
;
cMOAT
;
Canalicular multispecific organic anion transporter 1
;
cgr
;
cardiac glycoside reductase
;
CY
P450
s
;
cytochromes
P450
;
DPD
;
dihydropyrimidine dehydrogenase
;
DNA
;
deoxyribonucleic acid
;
EPHXs
;
epoxide hydrolases
;
DMI&rsquo
s ;
drug-microbiome interactions
;
FDA
;
Food and Drug Administration
;
GF
;
germ
刊名:Translational Research
出版年:2017
3.
Effect of sildenafil on human aromatase activity: From in vitro structural analysis to catalysis and inhibition in cells
作者:
Roberta Baravalle
a
;
Francesca Valetti
a
;
Gianluca Catucci
a
;
Giovanna Gambarotta
c
;
Mario Chiesa
d
;
Sara Maurelli
d
;
Elio Giamello
d
;
Ines Barone
e
;
Stefania Catalano
e
;
Sebastiano Andò
;
e
;
Giovanna Di Nardo
a
;
b
;
giovanna.dinardo@unito.it
;
Gianfranco Gilardi
a
;
b
;
gianfranco.gilardi@unito.it
关键词:
Aromatase inhibitors
;
Sildenafil
;
Cytochromes
P450
;
Estrogens
;
Breast cancer
刊名:The Journal of Steroid Biochemistry and Molecular Biology
出版年:2017
4.
Efficacy and safety of “Yahom” as a traditional Thai herbal therapy: A systematic review
作者:
Krongkarn Chootip
a
;
Nathorn Chaiyakunapruk
b
;
c
;
d
;
e
;
f
;
h
;
Noppamas Soonthornchareonnon
g
;
C. Norman Scholfield
b
;
h
;
Anjana Fuangchan
b
;
anjanaf@nu.ac.th
关键词:
2-AA
;
2-aminoanthracene
;
Ach
;
Acetylcholine
;
AF2
;
2-aminofluorene
;
Aq
;
Aqueous
;
BMI
;
Body mass index
;
BP
;
Blood pressure
;
BUN
;
Blood urea nitrogen
;
CYPs
;
Cytochromes
P450
;
DBP
;
Diastolic blood pressure
;
DPPH
;
2
;
2-diphenyl-1-picrylhydrazyl
;
ECG
;
Electrocardiogram
;
FRAP assay
;
Ferric reducing antioxidant power assay
;
HPLC
;
High Performance Liquid Chromatography
;
HR
;
Heart rate
;
IC50
;
Inhibitory concentration that cause 50% inhibition
;
ID50
;
Inhibitory dose that cause 50% inhibition
;
IP
;
Intraperit
刊名:Journal of Ethnopharmacology
出版年:2017
5.
Functional roles and substrate specificities of twelve
cytochromes
P450
belonging to CYP52 family in n-alkane assimilating yeast Yarrowia lipolytica
作者:
Ryo Iwama
a
;
Satoshi Kobayashi
a
;
Chiaki Ishimaru
a
;
Akinori Ohta
b
;
Hiroyuki Horiuchi
a
;
Ryouichi Fukuda
a
;
afukuda@mail.ecc.u-tokyo.ac.jp" class="auth_mail" title="E-mail the corresponding author
关键词:
CYP or
P450
;
cytochrome
P450
;
DCA
;
dicarboxylic acid
;
ER
;
endoplasmic reticulum
;
GC&ndash
;
MS
;
gas chromatography&ndash
;
mass spectrometry
;
ORF
;
open reading frame
;
RACE
;
rapid amplification of cDNA ends
;
TMD
;
transmembrane domain
刊名:Fungal Genetics and Biology
出版年:2016
6.
Effects of duration of phenytoin administration on mRNA expression of cytochrome
P450
and P-glycoprotein in the liver and small intestine of rats
作者:
Atsushi Kawase
;
kawase@phar.kindai.ac.jp" class="auth_mail" title="E-mail the corresponding author
;
Hiroyuki Tanaka
;
Toru Otori
;
Kenji Matsuyama
;
Masahiro Iwaki
关键词:
Phenytoin
;
Cytochromes
P450
;
Microsomes
;
mRNA
;
Liver
刊名:Asian Journal of Pharmaceutical Sciences
出版年:2016
7.
Induction of
cytochromes
P450
1A1 and 1A2 suppresses formation of DNA adducts by carcinogenic aristolochic acid I in rats in vivo
作者:
Helena Dračí
;
nská
;
a
;
Franti&scaron
;
ek Bá
;
rta
a
;
Kateřina Levová
;
a
;
Alena Hudecová
;
a
;
Michaela Moserová
;
a
;
Heinz H. Schmeiser
b
;
Klaus Kopka
b
;
c
;
Eva Frei
a
;
Volker M. Arlt
d
;
Marie Stiborová
;
a
;
stiborov@natur.cuni.cz" class="auth_mail" title="E-mail the corresponding author
关键词:
AA
;
aristolochic acid
;
AAI
;
aristolochic acid I
;
AAII
;
aristolochic acid II
;
AAIa
;
aristolochic acid Ia
;
AAN
;
aristolochic acid nephropathy
;
BEN
;
Balkan endemic nephropathy
;
bw
;
body weight
;
cT
;
cycle threshold
;
CYP
;
cytochrome
P450
;
dA-AAI
;
7-deoxyadenosine-N6-yl)aristolactam I
;
dA-AAII
;
7-deoxyadenosine-N6-yl)aristolactam II
;
dG-AAI
;
7-deoxyguanosin-N2-yl)aristolactam I
;
HPLC
;
high performance liquid chromatography
;
HUFs
;
Hupki (human TP53 knock-in) mouse fibroblasts
;
MROD
;
methoxyresorufin O-
刊名:Toxicology
出版年:2016
8.
Evaluation of possible inhibition of human liver drug metabolizing
cytochromes
P450
by two new acetylcholinesterase oxime-type reactivators
作者:
Alena Spicakova
a
;
Pavel Anzenbacher
a
;
Barbora Liskova
a
;
Kamil Kuca
c
;
d
;
kamil.kuca@fnhk.cz" class="auth_mail" title="E-mail the corresponding author
;
Josef Fusek
c
;
Eva Anzenbacherova
b
;
eva.anzenbacherova@upol.cz" class="auth_mail" title="E-mail the corresponding author
关键词:
Acetylcholinesterase
;
Cytochrome
P450
;
CYP
;
AChE reactivation
;
Oximes
;
K027
;
K203
;
Human microsomes
刊名:Food and Chemical Toxicology
出版年:2016
9.
Optical isomers of dihydropyridine calcium channel blockers display enantiospecific effects on the expression and enzyme activities of human xenobiotics-metabolizing
cytochromes
P450
作者:
Martina &Scaron
;
těpá
;
nková
;
a
;
Kristý
;
na Krasulová
;
b
;
c
;
Aneta Dořičá
;
ková
;
a
;
Ondřej Kurka
d
;
Pavel Anzenbacher
b
;
c
;
Zdeněk Dvořá
;
k
a
;
moulin@email.cz" class="auth_mail" title="E-mail the corresponding author
关键词:
AhR
;
Aryl Hydrocarbon Receptor
;
CCBs
;
calcium channel blockers
;
CYP
;
cytochrome
P450
;
DEX
;
dexamethasone
;
DMSO
;
dimethysulfoxide
;
GR
;
Glucocorticoid Receptor
;
HLMs
;
human liver microsomes
;
PXR
;
pregnane X receptor
;
RIF
;
rifampicin
;
TCDD
;
2
37 ;
8 tetrachlorodibenzo-p-dioxin
刊名:Toxicology Letters
出版年:2016
10.
Heterologous expression of fungal
cytochromes
P450
(CYP5136A1 and CYP5136A3) from the white-rot basidiomycete Phanerochaete chrysosporium: Functionalization with cytochrome b
5
in Escherichia coli
作者:
Mayumi Hatakeyama
m_hatakeyama@agr.kyushu-u.ac.jp" class="auth_mail" title="E-mail the corresponding author
;
Takuya Kitaoka
tkitaoka@agr.kyushu-u.ac.jp" class="auth_mail" title="E-mail the corresponding author
;
Hirofumi Ichinose
;
ichinose@agr.kyushu-u.ac.jp" class="auth_mail" title="E-mail the corresponding author
关键词:
P450
;
cytochrome
P450
monooxygenase
;
NTD
;
N-terminal domain
;
PR
;
proline-rich
;
CPR
;
cytochrome
P450
oxidoreductase
;
Cyt-b5
;
cytochrome b5
;
CB5R
;
NADH-dependent cytochrome b5 reductase
;
HEPES
;
[4-(2-hydroxyethyl)-1-piperazinyl]ethanesulfonic acid
;
EDTA
;
ethylenediaminetetraacetic acid
;
IPTG
;
isopropyl-1-thio-β-d-galactopyranoside
;
CHAPS
;
3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate
刊名:Enzyme and Microbial Technology
出版年:2016
1
2
3
4
5
6
7
8
9
按检索点细分(827)
题名(259)
关键词(122)
文摘(578)
按出版年细分(827)
2027年及以后(11)
2017年(4)
2016年(16)
2015年(6)
2013年(32)
2012年(26)
2011年(47)
2010年(36)
2009年(24)
2008年(42)
2007年(39)
2006年(37)
2005年(41)
2004年(44)
2003年(38)
2002年(35)
2001年(33)
2000年(43)
2000年及以前(273)
NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via
email
.