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内部出版物
在“
Elsevier电子期刊
”中,
命中:
16
条,耗时:小于0.01 秒
1.
Elaborate evaluation of serum and tissue oxidized LDL level with
darapladib
therapy: A feasible diagnostic marker for early atherogenesis
作者:
Teuku Heriansyah
1
;
Aditya Angela Adam
2
;
Titin Andri Wihastuti
2
;
wihastuti.fk@ub.ac.id
;
Mohammad Saifur Rohman
3
关键词:
OxLDL
;
Serum
;
Aorta
;
Lp-PLA2
;
Darapladib
;
Foam cell
刊名:Asian Pacific Journal of Tropical Biomedicine
出版年:2017
2.
Pharmacological inhibition of eicosanoids and platelet-activating factor signaling impairs zymosan-induced release of IL-23 by dendritic cells
作者:
Mario Rodrí
;
guez
a
;
Saioa Má
;
rquez
a
;
Olimpio Montero
b
;
Sara Alonso
c
;
Javier Garcí
;
a Frade
d
;
Mariano Sá
;
nchez Crespo
c
;
mscres@ibgm.uva.es" class="auth_mail" title="E-mail the corresponding author
;
Nieves Ferná
;
ndez
a
关键词:
Acetyl-CoA (PubChem CID
;
444493)
;
Arachidonoyl-CoA (PubChem CID
;
52922027)
;
Darapladib
(PubChem CID
;
9939609)
;
EDC (2-TEDC
;
PubChem CID
;
6069552)
;
12-HETE (PubChem CID
;
5353272)
;
12-HETE-d8 (PubChem CID
;
1436)
;
Leukotriene B4 (PubChem CID
;
5280492)
;
Leukotriene B4-d4 (PubChem CID
;
53394387)
;
Leukotriene C4 (PubChem CID
;
5280493)
;
Leukotriene E4 (PubChem CID
;
5280879)
;
Lyso-PAF C16
;
0 (PubChem CID
;
3983)
;
Montelukast (PubChem CID
;
5281040)
;
PGE2 (PubChem CID
;
5280360)
;
Platelet-activating factor (
刊名:Biochemical Pharmacology
出版年:2016
3.
La Lp-PLA
2
, marqueur d’inflammation vasculaire et de vulnérabilité de la plaque d’athérosclérose
作者:
D. Bonnefont-Rousselot
a
;
b
;
c
;
dominique.rousselot@aphp.fr" class="auth_mail" title="E-mail the corresponding author
关键词:
Athé
;
rogenè
;
se
;
Biomarqueur
;
Phospholipase A2 associé
;
e aux lipoproté
;
ines (Lp-PLA2)
刊名:Annales Pharmaceutiques Françaises
出版年:2016
4.
Darapladib
effect on circulating high sensitive troponin in patients with acute coronary syndromes
作者:
H¨¦ctor M. Garc¨ªa-Garc¨ªa
;
Rohit M. Oemrawsingh
;
Salvatore Brugaletta
;
Pascal Vranckx
;
Jennifer Shannon
;
Richard Davies
;
Eric Boersma
;
Patrick W. Serruys
关键词:
Atherosclerosis
;
High sensitive troponin I
;
Darapladib
刊名:Atherosclerosis
出版年:2012
5.
Targeting the Unstable Plaque in Acute Coronary Syndromes
作者:
Peter L. Thompson
;
S. Mark Nidorf
;
John Eikelboom
关键词:
acute coronary syndromes
;
atherosclerosis
;
canakinumab
;
colchicines
;
darapladib
;
methotrexate
;
plaque instability
刊名:Clinical Therapeutics
出版年:2013
6.
Triazole derivatives: A series of
Darapladib
analogues as orally active Lp-PLA
2
inhibitors
作者:
Kai Wang
&dagger
;
;
Wenwei Xu
&dagger
;
;
Wei Zhang
;
Mingguang Mo
;
Yiping Wang
;
ypwang@mail.shcnc.ac.cn
;
Jianhua Shen
;
jhshen@mail.shcnc.ac.cn
关键词:
Atherosclerosis
;
Lp-PLA2 inhibitor
;
Imidazole
;
Triazole
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2013
7.
Development of a seaweed derived platelet activating factor acetylhydrolase (PAF-AH) inhibitory hydrolysate, synthesis of inhibitory peptides and assessment of their toxicity using the Zebrafish larvae assay
作者:
Ciar谩n Fitzgerald
;
Eimear Gallagher
;
Paula O鈥機onnor
;
Jos茅 Prieto
;
Leticia Mora-Soler
;
Maura Grealy
;
Maria Hayes
关键词:
Atherosclerosis
;
Lp-PLA2
;
Enzyme inhibition
;
Darapladib
;
Platelet-activating factor acetylhydrolase
;
Bioactive peptides
;
Palmaria palmata
刊名:Peptides
出版年:December, 2013
8.
Selective inhibitors and tailored activity probes for lipoprotein-associated phospholipase A
2
作者:
Joseph M.G. Nagano
a
;
b
;
Ku-Lung Hsu
a
;
b
;
Landon R. Whitby
a
;
b
;
Micah J. Niphakis
a
;
b
;
Anna E. Speers
a
;
b
;
Steven J. Brown
a
;
c
;
Timothy Spicer
d
;
Virneliz Fernandez-Vega
d
;
Jill Ferguson
a
;
c
;
Peter Hodder
d
;
e
;
Prabhavathi Srinivasan
f
;
Tara D. Gonzalez
f
;
Hugh Rosen
a
;
c
;
Brian J. Bahnson
f
;
Benjamin F. Cravatt
a
;
b
;
cravatt@scripps.edu
关键词:
Phospholipase
;
Inhibitor
;
Screening
;
Proteomics
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2013
9.
Design and synthesis of imidazole and triazole derivatives as Lp-PLA
2
inhibitors and the unexpected discovery of highly potent quaternary ammonium salts
作者:
Kai Wang
;
Wenwei Xu
;
Yang Liu
;
Wei Zhang
;
Wenyi Wang
;
Jianhua Shen
;
jhshen@mail.shcnc.ac.cn
;
Yiping Wang
;
ypwang@mail.shcnc.ac.cn
关键词:
Bioisosteric replacement
;
Imidazole
;
Triazole
;
Lp-PLA2 inhibitor
;
Quaternary ammonium salt
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2013
10.
Study design and rationale for the clinical outcomes of the STABILITY Trial (STabilization of Atherosclerotic plaque By Initiation of
darapLadIb
TherapY) comparing
darapladib
versus placebo in patients with coronary heart disease
作者:
Harvey White
;
Claes Held
;
Ralph Stewart
;
David Watson
;
Robert Harrington
;
Andrzej Budaj
;
Ph. Gabriel Steg
;
Christopher P. Cannon
;
Susan Krug-Gourley
;
Janet Wittes
;
Trupti Trivedi
;
Elizabeth Tarka
;
Lar
刊名:American Heart Journal
出版年:2010
1
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