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在“Elsevier电子期刊”中，命中：19条，耗时：小于0.01 秒

1.The dual enzyme LRRK2 hydrolyzes GTP in both its GTPase and kinase domains in vitro

作者：Zhiyong Liu ; Andrew B. West ; ^{abwest@uab.edu}

关键词：PARK8 ; ROCO4 ; Dardarin ; Enzyme kinetics ; Manganese ; Nucleotide-binding pocket

刊名：Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

出版年：2017

2.Language deficits as a preclinical window into Parkinson’s disease: Evidence from asymptomatic parkin and dardarin mutation carriers

作者：Adolfo Garcia-Cordero^a ; ^b ; ^c ; Lucas Sedeno^b ; ^c ; Natalia Trujillo^a ; Yamile Bocanegra^a ; Diana Gomez^a ; David Pineda^a ; Andres Villegas^a ; William Arias^a ; Agustin Ibañ ; ez^b ; ^c ; ^d ; ^e ; ^f

刊名：International Journal of Psychophysiology

出版年：2016

3.Autophosphorylation in the Leucine-Rich Repeat Kinase 2 (LRRK2) GTPase Domain Modifies Kinase and GTP-Binding Activities

作者：Philip J. Webber¹ ; ² ; Archer D. Smith³ ; ⁴ ; ⁵ ; Saurabh Sen¹ ; ² ; Matthew B. Renfrow⁴ ; ⁵ ; James A. Mobley³ ; ⁴ ; ⁵ ; Andrew B. West¹ ; ² ; ^{abwest@uab.edu"" rel=""nofollow}

关键词：dardarin ; PARK8 ; Parkinson disease ; neurodegeneration ; serine/threonine kinase

刊名：Journal of Molecular Biology

出版年：2011

4.The dardarin G2019S mutation is a common cause of Parkinson's disease but not other neurodegenerative diseases

作者：Dena Hernandez ; Coro Paisan Ruiz ; Anthony Crawley ; Roneil Malkani ; John Werner ; Katrina Gwinn-Hardy ; Dennis Dickson ; Fabienne Wavrant DeVrieze ; John Hardy and Andrew Singleton

关键词：Parkinson's disease ; Parkinsonism ; Dementia ; LRRK2 ; Dardarin genetics

刊名：Neuroscience Letters

出版年：2005

5.Kinase activity is required for the toxic effects of mutant LRRK2/dardarin

作者：Elisa Greggio ; Shushant Jain ; Ann Kingsbury ; Rina Bandopadhyay ; Patrick Lewis ; Alice Kaganovich ; Marcel P. van der Brug ; Alexandra Beilina ; Jeff Blackinton ; Kelly Jean Thomas et al.

关键词：LRRK2 ; Kinase ; Parkinson's disease ; α ; -Synuclein ; Substantia nigra

刊名：Neurobiology of Disease

出版年：2006

6.Zeroing in on LRRK2-linked pathogenic mechanisms in Parkinson's disease

作者：Saskia Biskup ; Andrew B. West

关键词：Leucine-rich repeat kinase 2 ; Dardarin ; Neurodegeneration ; Kinase ; Movement disorder ; Molecular genetic

刊名：Biochimica et Biophysica Acta (BBA)/Molecular Basis of Disease

出版年：2009

7.A study of LRRK2 mutations and Parkinson's disease in Brazil

作者：Má ; rcia Mattos Gonç ; alves Pimentel ; Karla Cristina Vasconcelos Moura ; Clá ; udia Bueno Abdalla ; Joã ; o Santos Pereira ; Ana Lú ; cia Zuma de Rosso ; Denise Hack Nicaretta ; Má ; rio Camp

关键词：Parkinson's disease ; Leucine-rich repeat kinase 2 ; LRRK2 ; p.G2019S mutation ; Dardarin

刊名：Neuroscience Letters

出版年：2008

8.The biology and pathobiology of LRRK2: Implications for Parkinson's disease

作者：Darren J. Moore

关键词：LRRK2 ; PARK8 ; Dardarin ; Parkinsonism ; GTPase ; Kinase

刊名：Parkinsonism and Related Disorders

出版年：2008

9.Developmental regulation of leucine-rich repeat kinase 1 and 2 expression in the brain and other rodent and human organs: Implications for Parkinson’s disease

作者：M. Westerlund ; A.C. Belin ; A. Anvret ; P. Bickford ; L. Olson ; D. Galter

关键词：dardarin ; striatum ; in situ hybridization ; embryo ; aging

刊名：Neuroscience

出版年：2008

10.The R1441C mutation of LRRK2 disrupts GTP hydrolysis

作者：Patrick A. Lewis ; Elisa Greggio ; Alex ; ra Beilina ; Shushant Jain ; Acacia Baker ; Mark R. Cookson

关键词：LRRK2 ; Parkinson’ ; s disease ; GTPase ; Kinase ; Dardarin

刊名：Biochemical and Biophysical Research Communications

出版年：2007

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