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内部出版物
在“
Elsevier电子期刊
”中,
命中:
170
条,耗时:小于0.01 秒
1.
In vivo and in silico studies to identify mechanisms associated with Nurr1 modulation following early life exposure to permethrin in rats
作者:
Donatella Fedeli
a
;
&dagger
;
;
Maura Montani
b
;
&dagger
;
;
Laura Bordoni
c
;
Roberta Galeazzi
d
;
Cinzia Nasuti
a
;
Luí
;
sa Correia-Sá
;
e
;
Valentina F. Domingues
e
;
Maini Jayant
f
;
Vani Brahmachari
f
;
Luca Massaccesi
d
;
Emiliano Laudadio
d
;
Rosita Gabbianelli
a
;
rosita.gabbianelli@unicam.it
关键词:
3-PBA
;
3-phenoxybenzoic acid
;
BBB
;
blood&ndash
;
brain barrier
;
DNMTs
;
DNA methyltransferases
;
EDTA
;
ethylenediaminetetraacetic acid
;
LBD
;
Ligand Binding Domain
;
MSP
;
Methylation-Specific PCR
;
NOAEL
;
No Observed Adverse Effect Level
;
NuIP
;
Nurr1-interacting protein
;
PBS
;
phosphate buffered saline
;
PBS-T
;
PBS containing 0.05% Tween 20
;
PD
;
Parkinson&rsquo
;
s disease
;
PERM
;
permethrin
;
TH
;
tyrosine hydroxylase
刊名:Neuroscience
出版年:2017
2.
Epigenetic regulation of redox signaling in diabetic retinopathy: Role of Nrf2
作者:
Renu A. Kowluru
;
rkowluru@med.wayne.edu
;
Manish Mishra
关键词:
AGEs
;
advanced glycation end products
;
ARE
;
antioxidant response element
;
ATP
;
adenosine triphosphate
;
5mC
;
5-methyl cytosine
;
CBP
;
CREB-binding protein
;
p300
;
E1A binding protein P300
;
Dnmts
;
DNA methyl transferases
;
ETC
;
electron transport complex
;
FAD
;
flavin adenine dinucleotide
;
GCLC
;
glutamate-L-cysteine ligase
;
catalytic subunit
;
GSH
;
glutathione
;
GSSG
;
oxidized glutathione
;
H3K4
;
histone H3 lysine 4
;
H3K4me1
;
mono-methyl H3K4
;
H3K4me2
;
di-methyl H3K4
;
H3K4me3
;
tri-methyl H3K4
;
H3K9
;
hist
刊名:Free Radical Biology and Medicine
出版年:2017
3.
Epigenetic dysfunctional diseases and therapy for infection and inflammation
作者:
Saheli Samanta
a
;
Sheeja Rajasingh
a
;
Thuy Cao
a
;
Buddhadeb Dawn
a
;
Johnson Rajasingh
a
;
b
;
rjohnson9@kumc.edu
关键词:
Aza
;
5-aza 2 deoxycytidine
;
TSA
;
trichostatin A
;
MeCP2
;
methyl CpG binding protein 2
;
SLE
;
systemic lupus erythematosus
;
RA
;
rheumatoid arthritis
;
DNMTs
;
DNA methyltransferases
;
HDACs
;
histone deacetylases
;
HAT
;
histones acetyl transferases
;
HMT
;
histone methyl transferases
;
HDM
;
histone demethylases
;
MLH1
;
MutL homologue 1
;
CBP
;
CREB-binding protein
;
RASF
;
rheumatoid arthritis synovial fibroblasts
;
PBA
;
phenyl butyric acid
;
FOXO3
;
forkhead box O3
;
IRF1
;
interferon regulatory factor 1
;
STAT
;
sig
刊名:Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
出版年:2017
4.
Transcriptional and epigenetic phenomena in peripheral blood cells of monozygotic twins discordant for alzheimer’s disease, a case report
作者:
Claudio D&rsquo
;
Addario
a
;
b
;
cdaddario@unite.it
;
Sussy Bastias Candia
c
;
Beatrice Arosio
d
;
e
;
Martina Di Bartolomeo
a
;
Carlo Abbate
e
;
Alessandra Casè
;
d
;
Sanzio Candeletti
f
;
Patrizia Romualdi
f
;
Sarah Damanti
e
;
g
;
Mauro Maccarrone
b
;
h
;
1
;
Luigi Bergamaschini
d
;
i
;
1
;
Daniela Mari
d
;
e
;
1
关键词:
AD
;
Alzheimer&rsquo
;
s Disease
;
HADACs
;
histone deacetylases
;
APP
;
amyloid precursor protein
;
SIRT1
;
sirtuin 1
;
APOE
;
apolipoprotein E
;
PSEN1
;
presenilin 1
;
PIN1
;
peptidyl prolyl isomerase 1
;
PBMCs
;
peripheral blood mononuclear cells
;
DNMTs
;
DNA methyltransferases
;
Aβ
;
Amyloid-β
;
Ptau
;
Phosphorylated tau
;
CSF
;
cerebrospinal fluid
;
MCI
;
Mild Cognitive Impairment
;
H3K27me3
;
Histone 3 lysine 27 trimethylated
;
H3K4me3
;
Histone 3 lysine 4 trimethylated
;
H3K9Ac
;
Histone 3 lysine 9 acetylated
刊名:Journal of the Neurological Sciences
出版年:2017
5.
Prenatal nutrition and the risk of adult obesity: Long-term effects of nutrition on epigenetic mechanisms regulating gene expression
作者:
Estanislau Navarro
a
;
enavarro@idibell.cat
;
estanis.navarro@gmail.com
;
Anna N. Funtikova
b
;
c
;
d
;
Montserrat Fí
;
to
b
;
e
;
Helmut Schrö
;
der
b
;
c
关键词:
AS-RNA
;
antisense RNA
;
BAT
;
brown adipose tissue
;
BET
;
bromodomain and extraterminal
;
BMI
;
body mass index
;
CAD
;
coronary artery disease
;
CVD
;
cardiovascular diseases
;
DHA
;
docosahexaenoic acid
;
DMR
;
differentially-methylated region
;
DNMTs
;
DNA methyltransferases
;
DOAD
;
developmental origins of adult disease
;
DWF
;
Dutch Winter Famine
;
EGCG
;
(&minus
;
)-epigallocatechin gallate
;
eRNAs
;
enhancer RNAs
;
ERV
;
endogenous retrovirus
;
GEN
;
genistein
;
HAT
;
histone acetyl transferase
;
HDAC
;
histone deacetyl
刊名:The Journal of Nutritional Biochemistry
出版年:2017
6.
Methylation of Septin9 mediated by DNMT3a enhances hepatic stellate cells activation and liver fibrogenesis
作者:
Yuting Wu
wuyuting1302@sina.com
;
Fangtian Bu
;
Haixia Yu
;
Wanxia Li
;
Cheng Huang
;
Xiaoming Meng
;
Lei Zhang
;
Taotao Ma
;
Jun Li
;
lj@ahmu.edu.cn
关键词:
Sept9
;
septin9
;
ECM
;
extracellular matrix
;
HSCs
;
hepatic stellate cells
;
α-SMA
;
α-smooth muscle actin
;
Col1a1
;
type I collagen
;
TGF-β1
;
transforming growth factor-β1
;
HCC
;
hepatocellular cancer
;
5-azadC
;
5-aza-2&prime
;
-deoxycytidine
;
CRC
;
colorectal cancer
;
DNMTs
;
DNA methyltransferase enzymes
;
RRBS
;
reduced representation bisulfite sequencing
;
BSP
;
bisulfite pyrosequencing PCR
;
MSP
;
methylation-specific PCR
刊名:Toxicology and Applied Pharmacology
出版年:2017
7.
Acetylation Enhances TET2 Function in Protecting against Abnormal DNA Methylation during Oxidative Stress
作者:
Yang W. Zhang
1
;
Zhihong Wang
2
;
Wenbing Xie
1
;
Yi Cai
1
;
Limin Xia
1
;
Hariharan Easwaran
1
;
Jianjun Luo
1
;
4
;
Ray-Whay Chiu Yen
1
;
Yana Li
3
;
Stephen B. Baylin
1
;
5
;
sbaylin@jhmi.edu
关键词:
TET2
;
acetylation
;
DNA methylation
;
oxidative stress
;
5hmC
;
DNA demethylation
;
cancer
刊名:Molecular Cell
出版年:2017
8.
Discovery of novel DNA methyltransferase 3A inhibitors via structure-based virtual screening and biological assays
作者:
Zhiyuan Shao
a
;
f
;
Pan Xu
b
;
f
;
Wen Xu
c
;
f
;
Linjuan Li
b
;
d
;
Shien Liu
b
;
Rukang Zhang
b
;
d
;
Yu-Chih Liu
e
;
Chenhua Zhang
e
;
Shijie Chen
b
;
shijiechen@simm.ac.cn
;
Cheng Luo
b
;
cluo@simm.ac.cn
关键词:
Epigenetics
;
DNMT3A inhibitors
;
Virtual screening
;
Molecular docking
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2017
9.
PPARβ/δ activation protects against corticosterone-induced ER stress in astrocytes by inhibiting the CpG hypermethylation of microRNA-181a
作者:
Juan Ji
a
;
1
;
Xiao-Ning Zeng
b
;
1
;
Lu-Lu Cao
a
;
Ling Zhang
a
;
Zhan Zhao
a
;
Dan-Dan Yang
a
;
Xiu-Lan Sun
a
;
xiulans@njmu.edu.cn
关键词:
PPARβ/δ
;
ER stress
;
Methylation
;
miR181a
;
GRP78
刊名:Neuropharmacology
出版年:2017
10.
An oligodeoxyribonucleotide containing 5-formyl-2′-deoxycytidine (fC) at the CpG site forms a covalent complex with DNA cytosine-5 methyltransferases (
DNMTs
)
作者:
Kousuke Sato
a
;
Kyoji Kawamoto
a
;
Shintaro Shimamura
b
;
Satoshi Ichikawa
a
;
Akira Matsuda
a
;
关键词:
Epigenetic
;
Nucleic acids
;
5-Formyl-2&prime
;
-deoxycytidine
;
Covalent bond
;
DNA methyltransferase
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2016
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