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内部出版物
在“
Elsevier电子期刊
”中,
命中:
21
条,耗时:小于0.01 秒
1.
Bioreductively activatable prodrug conjugates of phenstatin designed to target tumor hypoxia
作者:
Blake A. Winn
a
;
Zhe Shi
a
;
Graham J. Carlson
a
;
Yifan Wang
a
;
Benson L. Nguyen
a
;
Evan M. Kelly
a
;
R. David Ross IV
a
;
Ernest Hamel
b
;
David J. Chaplin
a
;
c
;
Mary L. Trawick
a
;
Mary_Lynn_Trawick@baylor.edu
;
Kevin G. Pinney
a
;
Kevin_Pinney@baylor.edu
关键词:
BAPC
;
bioreductively activatable prodrug conjugate
;
CA1
;
combretastatin A-1
;
CA4
;
combretastatin A-4
;
Et3N
;
triethylamine
;
HPLC
;
high performance liquid chromatography
;
HRMS
;
high resolution mass spectrometry
;
MeOH
;
methanol
;
NaBH4
;
sodium borohydride
;
TLC
;
thin layer chromatography
;
THF
;
tetrahydrofuran
;
EtOAc
;
ethyl acetate
;
POR
;
NADPH cytochrome P450 oxidoreductase
;
DMP
;
Dess-Martin periodinane
;
DEAD
;
diethylazodicarboxylate
;
DIAD
;
diisopropyl azodicarboxylate
;
ADDP
;
1
;
1&prime
;
-(azodicarbonyl
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2017
2.
Neutral tris(azolyl)phosphanes: An intriguing class of molecules in chemistry
作者:
Arunabha Thakur
a
;
thakura@nitrkl.ac.in" class="auth_mail" title="E-mail the corresponding author
;
babuiitm07@gmail.com" class="auth_mail" title="E-mail the corresponding author
;
Dipendu Mandal
b
关键词:
acac
;
acetylacetonate
;
acacF6
;
hexafluoro acetylacetonate
;
AIBN
;
azobisisobutyronitrile
;
APH
;
aminophenol
;
Az
;
azole
;
CA
;
carbonic anhydrase
;
CatH2
;
catechol
;
CH2C6H5
;
benzyl
;
Cp
;
cyclopentadienyl
;
Cy
;
cyclohexyl
;
cym
;
cymene
;
DIBQ
;
o-diiminobenzoquinone
;
DMF
;
dimethylformamide
;
EGDMA
;
ethyleneglycol dimethacrylate
;
Et
;
ethyl
;
Et3N
;
triethyl amine
;
Fc
;
ferrocene
;
Im
;
imidazole
;
iPr
;
iso-propyl
;
ISQ
;
o-iminobenzosemiquinone
;
Me
;
methyl
;
nBu
;
butyl
;
NHC
;
N-heterocyclic carbene
;
NMI
;
N-methyl imida
刊名:Coordination Chemistry Reviews
出版年:2016
3.
A green approach for the synthesis of 3,4-dihydropyrimidin-2-(1H)-ones (and -thiones) using N,N-diethyl-N-sulfoethanaminium hydrogen sulfate
作者:
Abdolkarim Zare
;
abdolkarimzare@pnu.ac.ir" class="auth_mail" title="E-mail the corresponding author
;
abdolkarimzare@yahoo.com" class="auth_mail" title="E-mail the corresponding author
;
Zahra Nasouri
关键词:
SO3H-containing ionic liquid
;
N
;
N-Diethyl-N-sulfoethanaminium hydrogen sulfate {[
Et3N
&ndash
;
SO3H]HSO4}
;
3
;
4-Dihydropyrimidin-2-(1H)-one
;
3
;
4-dihydropyrimidin-2-(1H)-thione
;
Arylaldehyde
;
β-Ketoester
刊名:Journal of Molecular Liquids
出版年:2016
4.
Structure-based design of a new series of N-(piperidin-3-yl)pyrimidine-5-carboxamides as renin inhibitors
作者:
Yasuhiro Imaeda
a
;
yasuhiro.imaeda@takeda.com" class="auth_mail" title="E-mail the corresponding author
;
Michiko Tawada
a
;
Shinkichi Suzuki
a
;
Masaki Tomimoto
a
;
Mitsuyo Kondo
a
;
Naoki Tarui
a
;
Tsukasa Sanada
a
;
Ray Kanagawa
a
;
Gyorgy Snell
b
;
Craig A. Behnke
b
;
&dagger
;
;
Keiji Kubo
a
;
Takanobu Kuroita
a
关键词:
AcOH
;
acetic acid
;
Ang I
;
angiotensin I
;
Ang II
;
angiotensin II
;
AUC
;
area under the blood concentration&ndash
;
time curve
;
C5min
;
concentration in plasma 5
;
min after administration
;
CLtotal
;
total clearance
;
Cmax
;
maximum concentration in plasma
;
DIEA
;
N
;
N-diisopropylethylamine
;
Et3N
;
triethylamine
;
EtOAc
;
ethyl acetate
;
EtOH
;
ethanol
;
F
;
rat bioavailability
;
HAC
;
heavy atom count
;
HOBt
;
1-hydroxybenzotriazole hydrate
;
hPRA
;
human plasma renin activity
;
i-PrOH
;
isopropanol
;
LE
;
ligand effic
刊名:Bioorganic & Medicinal Chemistry
出版年:2016
5.
Design synthesis and structure-activity relationship of 5-substituted (tetrahydronaphthalen-2yl)methyl with N-phenyl-N-(piperidin-2-yl)propionamide derivatives as opioid ligands
作者:
Srinivas Deekonda
a
;
David Rankin
b
;
Peg Davis
b
;
Josephine Lai
b
;
Todd. W. Vanderah
b
;
Frank Porecca
b
;
Victor J. Hruby
a
;
hruby@email.arizona.edu" class="auth_mail" title="E-mail the corresponding author
关键词:
GPCR
;
G protein-coupled receptor
;
MOR
;
Mu opioid receptor
;
DOR
;
delta opioid receptor
;
Boc
;
tert-butyloxycarbonyl
;
NaOtBu
;
sodium tert-butoxide
;
Et3N
;
triethylamine
;
HCl
;
hydrochloric acid
;
BH3-SMe2
;
borane dimethylsulfide
;
DHP
;
dihydropyran
;
PPTS
;
pyridinium p-toluenesulfonate
;
Ph3P
;
triphenylphosphine
;
Na(OAc)3BH
;
sodium triacetoxyborohydride
;
DCE
;
dichloroethane
;
DIPEA
;
N
;
N-diisopropylethylamine
;
ACN
;
acetonitrile
;
DCM
;
dichloromethane
;
rt
;
room temperature
;
CHO
;
Chinese hamster ovary
;
dALEA
刊名:Bioorganic & Medicinal Chemistry
出版年:2016
6.
Discovery of a novel small molecule agonist scaffold for the APJ receptor
作者:
Sanju Narayanan
a
;
Rangan Maitra
a
;
Jeffery R. Deschamps
b
;
Katherine Bortoff
a
;
James B. Thomas
a
;
Yanyan Zhang
a
;
Keith Warner
a
;
Vineetha Vasukuttan
a
;
Ann Decker
a
;
Scott P. Runyon
a
;
srunyon@rti.org" class="auth_mail" title="E-mail the corresponding author
关键词:
AT1
;
angiotensin 2 receptor 1
;
CB1
;
cannabinoid receptor 1
;
CB2
;
cannabinoid receptor 2
;
NPS
;
neuropeptide S receptor
;
NTR-1
;
neurotensin receptor 1
;
BOP
;
benzotriazole-1-yl-oxy-tris-(dimethylamino)-phosphonium hexafluorophosphate
;
LiOH·
;
H2O
;
lithium hydroxide monohydrate
;
TFA
;
trifluroacetic acid
;
HCl
;
hydrochloric acid
;
Et3N
;
triethylamine
;
DCM
;
dichloromethane
;
THF
;
tetrahydrofuran
;
MeOH
;
methanol
;
SAR
;
structure activity relationship
;
TLC
;
thin layer chromatography
刊名:Bioorganic & Medicinal Chemistry
出版年:2016
7.
Et
3
N mediated synthesis of polysubstituted thiophenes from 伪-oxo ketene dithioacetals
作者:
Xiaoli Kan
a
;
Xiaobing Yang
a
;
Fangzhong Hu
a
;
fzhu@nankai.edu.cn" class="auth_mail" title="E-mail the corresponding author
;
Yang Wang
a
;
Ying Liu
a
;
Xiaomao Zou
a
;
Hengyu Li
a
;
Hao Li
a
;
Qichun Zhang
b
;
c
;
qczhang@ntu.edu.sg" class="auth_mail" title="E-mail the corresponding author
关键词:
Et3N
mediation
;
Polysubstituted thiophenes
;
伪-Oxo S-methyl-S-propargyl ketenes
;
Cyclization
刊名:Tetrahedron Letters
出版年:2015
8.
Biodegradable poly(ester amide)s - A remarkable opportunity for the biomedical area: Review on the synthesis, characterization and applications
作者:
Ana C. Fonseca
;
ana.clo.fonseca@gmail.com" class="auth_mail
;
Maria H. Gil
;
Pedro N. Simõ
;
es
关键词:
BAAD
;
bis-伪-(l-amino acid)-伪
;
蠅-alkylene diesters
;
蓻-CL
;
蓻-caprolactone
;
伪-CT
;
伪-chymotrypsin
;
DDS
;
drug delivery system
;
DMA
;
N
;
N&prime
;
-dimethylacetamide
;
DMF
;
N
;
N&prime
;
-dimethylformamide
;
DMSO
;
dimethylsulfoxide
;
DNA
;
deoxyribonucleic acid
;
Et3N
;
triethylamine
;
GA
;
glycolic acid
;
GDS
;
gene delivery system
;
HCASMCs
;
human coronary artery smooth muscle cells
;
LA
;
lactic acid
;
l-LA
;
l-lactic acid
;
MTT
;
3-(4
;
5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulphofenyl)-2H-tetrazolium inner
刊名:Progress in Polymer Science
出版年:July 2014
9.
New antiprotozoal agents: Their synthesis and biological evaluations
作者:
Ram Shankar Upadhayaya
;
ram@boc.uu.se
;
Shailesh S. Dixit
;
Andras Fö
;
ldesi
;
Jyoti Chattopadhyaya
;
jyoti@boc.uu.se
关键词:
CC50
;
concentration of inhibitor resulting in 50 % parasite growth inhibition
;
DCM
;
dichloromethane
;
DMF
;
N
;
N-dimethylformamide
;
DMSO
;
dimethyl sulfoxide
;
EDC·
;
HCl
;
1-ethyl-3-(3-dimethyllaminopropyl)carbodiimide hydrochloride
;
Et3N
;
triethylamine
;
Et
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2013
10.
Glutathione conjugation attenuates biological activities of 6-dehydroshogaol from ginger
作者:
Guodong Zhang
;
1
;
gdzhang@ucdavis.edu
;
Viriya Nitteranon
1
;
Lok Yan Chan
;
Kirk L. Parkin
;
klparkin@wisc.edu
关键词:
ASC
;
ascorbic acid
;
COX-2
;
cyclooxygenase-2
;
Cys
;
cysteine
;
6-DHSG
;
6-dehydroshogaol
;
Et3N
;
triethylamine
;
GSH
;
glutathione (reduced)
;
GST
;
glutathione S-transferase
;
GS-curcumin
;
glutathione conjugate of curcumin
;
GS-6-DHSG
;
glutathione conjugate of 6-DH
刊名:Food Chemistry
出版年:2013
1
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