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在“Elsevier电子期刊”中，命中：71条，耗时：小于0.01 秒

1.Chronic Over-expression of Fibroblast Growth Factor 21 Increases Bile Acid Biosynthesis by Opposing FGF15/19 Action

作者：Jun Zhang^a ; Jamila Gupte^a ; Yan Gong^a ; Jennifer Weiszmann^a ; Yuan Zhang^c ; Ki Jeong Lee^b ; William G. Richards^b ; Yang Li^a ; ^{yangl@amgen.com}

关键词：FGF21 ; FGF19 ; βKlotho ; FGFR4 ; Bile acid metabolism

刊名：EBioMedicine

出版年：2017

2.Sinapine reverses multi-drug resistance in MCF-7/dox cancer cells by downregulating FGFR4/FRS2α-ERK1/2 pathway-mediated NF-κB activation

作者：Ying Guo^b ; Yuanyuan Ding^c ; Tao Zhang^c ; ^{taozhang@mail.xjtu.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Hongli An^a ; ^{anhongli@mail.xjtu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：Sinapine ; Doxorubicin ; MCF-7/dox ; P-glycoprotein ; NF-κB ; FGFR4

刊名：Phytomedicine

出版年：2016

3.105A - First-in-human study of BLU-554, a potent, highly-selective FGFR4 inhibitor designed for hepatocellular carcinoma (HCC) with FGFR4 pathway activation

作者：R. Kim ; S. Sharma ; T. Meyer ; D. Sarker ; T. Macarulla ; M. Sung ; S.P. Choo ; H. Shi ; O. Schmidt-Kittler ; C. Clifford ; B. Wolf ; J.M. Llovet

刊名：European Journal of Cancer

出版年：2016

4.Therapeutics Targeting FGF Signaling Network in Human Diseases

作者：Masaru Katoh¹ ; ^{mkatoh-kkr@umin.ac.jp" class="auth_mail" title="E-mail the corresponding author}

关键词：epithelial-to-mesenchymal transition ; erdafitinib ; infigratinib ; immune-checkpoint blocker ; miRNA ; myeloproliferative syndrome.

刊名：Trends in Pharmacological Sciences

出版年：2016

5.O048 : First selective small molecule inhibitor of FGFR4 for the treatment of hepatocellular carcinomas with an activated FGFR4 signaling pathway

刊名：Journal of Hepatology

出版年：2015

6.Fibroblast growth factor receptor 4 promotes progression and correlates to poor prognosis in cholangiocarcinoma

作者：Yun-Fei Xu^a ; Xiao-Qing Yang^b ; Xiao-Fei Lu^c ; Sen Guo^a ; Yi Liu^a ; Mohammad Iqbal^a ; Shang-Lei Ning^a ; Hui Yang^a ; Ning Suo^d ; Yu-Xin Chen^a ; ^{yxu8@bidmc.harvard.edu" class="auth_mail} ; ^{cyx2012@163.com" class="auth_mail}

关键词：FGFR4 ; fibroblast growth factor receptor 4 ; IHCC ; intrahepatic cholangicolangcinoma ; PHCC ; perihilar cholangiocarcinoma ; EMT ; epithelial&ndash ; mesenchymal transition ; CCA ; cholangiocarcinoma

刊名：Biochemical and Biophysical Research Communications

出版年：28 March, 2014

7.620 FGFR4 overexpression is a possible indicator of radiotherapy resistance in CRC

刊名：European Journal of Cancer

出版年：2015

8.New paradigms in the treatment of hepatic cholestasis: From UDCA to FXR, PXR and beyond

作者：Ulrich Beuers¹ ; ^{u.h.beuers@amc.uva.nl" class="auth_mail" title="E-mail the corresponding author} ; Michael Trauner² ; Peter Jansen¹ ; Raoul Poupon³

关键词：AE2 ; anion exchanger 2 ; ASBT ; apical sodium bile salt transporter ; BA ; bile acid ; CA ; cholic acid ; CDCA ; chenodeoxycholic acid ; CFALD ; cystic fibrosis-associated liver disease ; CFTR ; cystic fibrosis transmembrane conductance regulator ; DCA ; deoxycholic acid ; FGF ; fibroblast growth factor ; FXR ; farnesoid X receptor ; GR ; glucocorticoid receptor ; IBD ; inflammatory bowel disease ; ICP ; intrahepatic cholestasis of pregnancy ; LCA ; lithocholic acid ; LPAC ; low phospholipid-associated cholelithiasis ; MAPK

刊名：Journal of Hepatology

出版年：2015

9.Soluble FGFR4 extracellular domain inhibits FGF19-induced activation of FGFR4 signaling and prevents nonalcoholic fatty liver disease

作者：Qiang Chen^a ; ^b ; ¹ ; Yuan Jiang^a ; ¹ ; Yuan An^a ; Na Zhao^a ; Yang Zhao^a ; Chundong Yu^a ; ^{cdyu@xmu.edu.cn"" rel=""nofollow}

关键词：FGFR4 ; Extracellular domain ; NAFLD ; PPARα

刊名：Biochemical and Biophysical Research Communications

出版年：2011

10.Sinapine as an active compound for inhibiting the proliferation of Caco-2 cells via downregulation of P-glycoprotein

作者：Ying Guo^a ; ¹ ; Hongli An^b ; ¹ ; Liuxin Feng^a ; Qi Liu^a ; Sicen Wang^a ; Tao Zhang^a ; ^{taozhang@mail.xjtu.edu.cn" class="auth_mail}

关键词：ERK1/2 ; extracellular regulating kinase 1/2 ; FGFR4 ; fibroblast growth factor receptor 4 ; FRS2伪 ; fibroblast growth factor receptor substrate 2伪 ; MAPK ; mitogen-activated protein kinase ; MDR ; multiple drug resistance ; P-gp ; P-glycoprotein

刊名：Food and Chemical Toxicology

出版年：May, 2014

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