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内部出版物
在“
Elsevier电子期刊
”中,
命中:
4
条,耗时:小于0.01 秒
1.
Discovery of N-[[1-[2-(tert-butylcarbamoylamino)ethyl]-4-(hydroxymethyl)-4-piperidyl]methyl]-3,5-dichloro-benzamide as a selective T-type calcium channel (Ca
v
3.2) inhibitor
作者:
Fabrizio Giordanetto
a
;
fabrizio.giordanetto@astrazeneca.com
;
Andreas Wå
;
llberg
a
;
Laurent Knerr
a
;
Nidhal Selmi
a
;
Victoria Ullah
a
;
Fredrik
Thorstensson
a
;
Å
;
sa Lindelö
;
f
a
;
Staffan Karlsson
a
;
Grigorios Nikitidis
a
;
Antonio Llinas
b
;
Qing-Dong Wang
c
;
Anders Lindqvist
c
;
Å
;
got Hö
;
gberg
c
;
Emma Lindhardt
b
;
Annika Å
;
strand
c
;
Gö
;
ran Duker
c
关键词:
Calcium channel inhibition
;
Cav3.2
;
T-type calcium channels
;
Atrial fibrillation
;
Atrial remodelling
;
Mibefradil
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2013
2.
Discovery of N-(1-adamantyl)-2-(4-alkylpiperazin-1-yl)acetamide derivatives as T-type calcium channel (Ca
v
3.2) inhibitors
作者:
Fabrizio Giordanetto
a
;
fabrizio.giordanetto@astrazeneca.com"" rel=""nofollow
;
Laurent Knerr
a
;
Nidhal Selmi
a
;
Antonio Llinà
;
s
b
;
Anders Lindqvist
c
;
Qing-Dong Wang
c
;
Pernilla Stå
;
hlberg
a
;
Fredrik
Thorstensson
a
;
Victoria Ullah
a
;
Kristina Nilsson
a
;
Gavin O’
;
Mahony
a
;
Å
;
got Hö
;
gberg
c
;
Emma Lindhardt
b
;
Annika Å
;
strand
c
;
Gö
;
ran Duker
c
关键词:
Calcium channel inhibition
;
Ca
v
3.2
;
T-type calcium channels
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2011
3.
Synthesis of novel potent hepatitis C virus NS3 protease inhibitors: Discovery of 4-hydroxy-cyclopent-2-ene-1,2-dicarboxylic acid as a N-acyl-
l-hydroxyproline bioisostere
作者:
Fredrik
Thorstensson
;
Fredrik
Wå
;
ngsell
;
Ingemar Kvarnströ
m ;
Lotta Vrang
;
Elizabeth Hamelink
;
Katarina Jansson
;
Anders Hallberg
;
Å
;
sa Rosenquist
;
Bertil Samuelsson
关键词:
HCV
;
NS3
;
Protease inhibitor
;
N
-Acyl-l-hydroxyproline mimic
;
4-Hydroxy-cyclopent-2-ene-1
;
2-dicarboxylic acid
;
Cyclopentene
刊名:Bioorganic and Medicinal Chemistry
出版年:2007
4.
Novel potent macrocyclic inhibitors of the hepatitis C virus NS3 protease: Use of cyclopentane and cyclopentene P2-motifs
作者:
Marcus Bä
;
ck
;
Per-Ola Johansson
;
Fredrik
Wå
;
ngsell
;
Fredrik
Thorstensson
;
Ingemar Kvarnströ
m ;
Susana Ayesa
;
Horst Wä
;
hling
;
Mikael Pelcman
;
Katarina Jansson
;
Stefan Lindströ
m ;
Ha
关键词:
HCV
;
NS3 protease
;
Macrocyclic inhibitors
;
Cyclopentane and Cyclopentene derived P2 templates
刊名:Bioorganic and Medicinal Chemistry
出版年:2007
1
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