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内部出版物
在“
Elsevier电子期刊
”中,
命中:
519
条,耗时:小于0.01 秒
1.
Improving performance of
FxR
LS algorithm for active noise control of impulsive noise
作者:
Ayesha Zeb
;
ayeshazeb79@ee.ceme.edu.pk" class="auth_mail" title="E-mail the corresponding author
;
Alina Mirza
;
Qasim Umar Khan
;
Shahzad A. Sheikh
关键词:
Active noise control
;
Impulsive noise
;
Stable distributions
;
FxR
LS algorithm
刊名:Applied Acoustics
出版年:2017
2.
Protective effects of dioscin against doxorubicin-induced nephrotoxicity via adjusting
FXR
-mediated oxidative stress and inflammation
作者:
Yimeng Zhang
;
Youwei Xu
;
Yan Qi
;
Lina Xu
;
Shasha Song
;
Lianhong Yin
;
Xufeng Tao
;
Yuhong Zhen
;
Xu Han
;
Xiaodong Ma
;
Kexin Liu
;
Jinyong Peng
;
jinyongpeng2014@163.com
;
jinyongpeng2005@163.com
关键词:
Dox
;
doxorubicin
;
FXR
;
the farnesoid X receptor
;
AMPKα
;
AMP- activated protein kinase α
;
HO-1
;
hemeoxygenase-1
;
GST
;
glutathione-s-transferase
;
Nrf2
;
NF-E2-related factor 2
;
BUN
;
blood urea nitrogen
;
Cr
;
creatinine
;
HMGB1
;
high mobility group box 1
;
NF-κB
;
nuclear factor kappa B
;
IL-1β
;
interleukin-1β
;
IL-6
;
interleukin-6
;
TNF-α
;
tumor necrosis factor alpha
;
siRNA
;
small interfering RNA
;
H12
;
helix12
刊名:Toxicology
出版年:2017
3.
Cardiopulmonary protective effects of the selective
FXR
agonist obeticholic acid in the rat model of monocrotaline-induced pulmonary hypertension
作者:
Linda Vignozzi
a
;
Annamaria Morelli
b
;
Ilaria Cellai
a
;
Sandra Filippi
c
;
Paolo Comeglio
a
;
Erica Sarchielli
b
;
Elena Maneschi
a
;
Gabriella Barbara Vannelli
b
;
Luciano Adorini
d
;
Mario Maggi
a
;
e
;
mario.maggi@unifi.it
关键词:
ACE2
;
angiotensin-converting enzyme 2
;
Ach
;
acetylcholine
;
BA
;
bile acid
;
BMP2
;
bone morphogenetic protein 2
;
BMPR1A
;
bone morphogenetic protein receptor 1-a
;
BW
;
body weight
;
CDCA
;
chenodeoxycholic acid
;
cGMP
;
cyclic guanosine monophosphate
;
COX2
;
cyclooxygenase-2
;
ECs
;
endothelial cells
;
ET-1
;
endothelin-1
;
ETA
;
endothelin receptor type A
;
ETB
;
endothelin receptor type B
;
FXR
;
farnesoid X receptor
;
GCSa3
;
guanylate cyclase subunit type 1a3
;
GCSb3
;
guanylate cyclase subunit type 1b3
;
IL-1β
;
int
刊名:The Journal of Steroid Biochemistry and Molecular Biology
出版年:2017
4.
Obeticholic acid protects against carbon tetrachloride-induced acute liver injury and inflammation
作者:
Da-Gang Zhang
a
;
1
;
Cheng Zhang
b
;
1
;
Jun-Xian Wang
a
;
Bi-Wei Wang
b
;
Hua Wang
b
;
Zhi-Hui Zhang
b
;
Yuan-Hua Chen
b
;
Yan Lu
c
;
Li Tao
c
;
Jian-Qing Wang
c
;
Xi Chen
a
;
;
De-Xiang Xu
b
;
xudex@126.com
关键词:
CCl4
;
carbon tetrachloride
;
CDCA
;
chenodeoxycholic acid
;
ERK
;
extracellular regulated protein kinase
;
FXR
;
farnesoid X receptor
;
IkB
;
inhibitor of kB
;
IL
;
interleukin
;
KC
;
keratinocyte-derived chemokine
;
MAPK
;
mitogen-activated protein kinase
;
MCP-1
;
monocyte chemotactic protein 1
;
MIP
;
macrophage inflammatory protein
;
NF-κB
;
nuclear factor kappa B
;
OCA
;
obeticholic acid
;
TNF-α
;
tumor necrosis factor alpha
;
TUNEL
;
terminal dUTP nick-end labeling
;
UDCA
;
ursodeoxycholic acid
刊名:Toxicology and Applied Pharmacology
出版年:2017
5.
Dihydroartemisinin protects against alcoholic liver injury through alleviating hepatocyte steatosis in a farnesoid X receptor-dependent manner
作者:
Wenxuan Xu
a
;
Chunfeng Lu
a
;
Lu Yao
a
;
Feng Zhang
a
;
Jiangjuan Shao
a
;
Shizhong Zheng
a
;
b
;
nytws@163.com
关键词:
ALD
;
alcoholic liver disease
;
ALP
;
alkaline phosphatase
;
ALT
;
alanine aminotransferase
;
AST
;
aspartate aminotransferase
;
BSEP
;
bile salt export pump
;
CPT1
;
carnitine palmitoyltransferase I
;
CYP7A1
;
cholesterol 7-alpha hydroxy-lase
;
DHA
;
dihydroartemisininx
;
DMEM
;
Dulbecco's modified Eagle's medium
;
DMSO
;
dimethyl sulfoxide
;
FAS
;
fatty acid synthase
;
FBS
;
fetal bovine serum
;
FGF15
;
fibroblast growth factor 15
;
FXR
;
farnesoid X receptor
;
GAPDH
;
Glyceraldehyde phosphate dehydrogenase
;
H&E
;
haematox
刊名:Toxicology and Applied Pharmacology
出版年:2017
6.
Effect of cholecystectomy on bile acids as well as relevant enzymes and transporters in mice: Implication for pharmacokinetic changes of rifampicin
作者:
Fan Zhang
a
;
b
;
Hongyan Qin
b
;
Yanshu Zhao
a
;
b
;
Yuhui Wei
b
;
Lili Xi
b
;
Zhi Rao
b
;
Jianping Zhang
b
;
Yanrong Ma
b
;
Yingting Duan
a
;
b
;
Xinan Wu
b
;
xinanwu6511@126.com
关键词:
Asbt
;
apical sodium-dependent bile acids transporter
;
BAs
;
bile acids
;
Bsep
;
bile salt export pump
;
β-MCA
;
β-muricholic acid
;
CA
;
cholic acid
;
CDCA
;
chenodeoxycholic acid
;
Cyp3a11
;
cytochrome P450 3a11 (human CYP3A4)
;
Cyp7a1
;
cholesterol 7α-hydroxylase cytochrome P450 7a1
;
DCA
;
deoxycholic acid
;
Fxr
;
farnesoid X receptor
;
G-
;
glycine conjugated bile acid
;
HDCA
;
hyodesoxycholic acid
;
LCA
;
lithocholic acid
;
Mrp2
;
multidrug resistance-associated protein 2
;
NDCA
;
demethylation deoxycholic acid
;
NRs
刊名:European Journal of Pharmaceutical Sciences
出版年:2017
7.
Characterization of stem cell-derived liver and intestinal organoids as a model system to study nuclear receptor biology
作者:
Ingrid T.G.W. Bijsmans
a
;
Alexandra Milona
a
;
Noortje Ijssennagger
a
;
Ellen C.L. Willemsen
a
;
José
;
M. Ramos Pittol
a
;
Johan W. Jonker
b
;
Katja Lange
c
;
Guido J.E.J. Hooiveld
c
;
Saskia W.C. van Mil
a
;
S.W.C.vanMil@umcutrecht.nl
关键词:
ChIP
;
chromatin immunoprecipitation
;
DIC
;
differential interference contrast
;
DM
;
differentiation medium
;
DSG
;
Di(N-succinimidyl) glutarate
;
EM
;
expansion medium
;
Fxr
;
farnesoid x receptor
;
IPA
;
Ingenuity Pathway Analysis
;
Lxr
;
Liver x receptor
;
NR
;
nuclear receptor
;
OCA
;
obeticholic acid
;
Ppar
;
Peroxisome proliferator-activated receptor
;
RMA
;
robust multiarray analysis
;
Rosi
;
Rosiglitazone
刊名:Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
出版年:2017
8.
Acetylated deoxycholic (DCA) and cholic (CA) acids are potent ligands of pregnane X (PXR) receptor
作者:
Alejandro Carazo
a
;
Lucie Hyrsova
a
;
Jan Dusek
a
;
Hana Chodounska
b
;
Alzbeta Horvatova
a
;
Karel Berka
c
;
Vaclav Bazgier
c
;
Hongying Gan-Schreier
d
;
Waleé
;
Chamulitrat
d
;
Eva Kudova
b
;
Petr Pavek
a
;
petr.pavek@faf.cuni.cz
关键词:
BA
;
bile acid
;
CA
;
cholic acid
;
CDCA
;
chenodeoxycholic acid
;
CYP
;
cytochrome P450
;
DCA
;
deoxycholic acid
;
6-ECDCA
;
6α-ethyl-chenodeoxycholic acid
;
obeticholic acid
;
FXR
;
farnesoid X receptor
;
LBD
;
ligand binding domain
;
LCA
;
lithocholic acid
;
PXR
;
pregnane X receptor
;
TR-FRET
;
time-resolved fluorescence energy transfer
;
VDR
;
vitamin D receptor
刊名:Toxicology Letters
出版年:2017
9.
NAFLD is associated with methylation shifts with relevance for the expression of genes involved in lipoprotein particle composition
作者:
Jessica Mwinyi
a
;
jessica.mwinyi@neuro.uu.se
;
Adrian E. Boströ
;
m
a
;
Claudia Pisanu
b
;
Susan K. Murphy
c
;
Wiebke Erhart
d
;
Clemens Schafmayer
e
;
Jochen Hampe
f
;
Cynthia Moylan
g
;
h
;
Helgi B. Schiö
;
th
a
关键词:
1-25-diOH D
;
dihydroxyvitamine D
;
25-OH D
;
25-hydroxyvitamin D
;
APO
;
apolipoprotein
;
BMI
;
body mass index
;
ER
;
endoplasmic reticulum
;
FC
;
free cholesterol
;
FFAs
;
free fatty acids
;
FGF-2
;
fibroblast growth factor 2
;
FXR
ɑ
;
farnesoid X receptor α
;
HDL
;
high density lipoprotein
;
LDL
;
low density lipoprotein
;
NAFLD
;
nonalcoholic fatty liver disease
;
NASH
;
nonalcoholic steatohepatitis
;
SS
;
simple steatosis
;
MS
;
metabolic syndrome
;
LXRα
;
Liver X Receptor α
;
PGC-1α
;
coactivator 1α
;
PPAR
;
peroxisome prol
刊名:Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
出版年:2017
10.
Feeding the microbiota-gut-brain axis: diet, microbiome, and neuropsychiatry
作者:
Kiran V. Sandhu
a
;
Eoin Sherwin
a
;
Harrië
;
t Schellekens
a
;
b
;
Catherine Stanton
a
;
c
;
d
;
Timothy G. Dinan
a
;
c
;
John F. Cryan
a
;
b
;
j.cryan@ucc.ie
关键词:
ASD
;
Autism spectrum disorder
;
ADHD
;
Attention-deficit hyperactive disorder
;
AMPK
;
AMP-activated protein kinase
;
ANS
;
Autonomic nervous system
;
BDNF
;
Brain-derived neurotrophic factor
;
BMI
;
Body mass index
;
BCFA
;
Branched chain fatty acid
;
CCK
;
Cholecystokinin
;
CNS
;
Central nervous system
;
CREB
;
cAMP response element-binding protein
;
DA
;
Dopamine
;
EECs
;
Enteroendocrine cells
;
ENS
;
Enteric nervous system
;
FOS
;
Fructo-oligosaccharides
;
FXR
;
Farnesoid X receptor
;
GOS
;
Galacto-oligosaccharides
;
GF
刊名:Translational Research
出版年:2017
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