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内部出版物
在“
Elsevier电子期刊
”中,
命中:
49
条,耗时:小于0.01 秒
1.
Progress and problems with the use of suicide genes for targeted cancer therapy
作者:
Zahra Karjoo
a
;
Xuguang Chen
a
;
Arash Hatefi
a
;
b
;
ahatefi@pharmacy.rutgers.edu" class="auth_mail" title="E-mail the corresponding author
关键词:
Enzyme prodrug
;
Bystander effect
;
Cancer Gene therapy
;
GDEPT
;
Ganciclovir
;
Nitroreductase
;
Cytosine deaminase
;
Thymidine kinase
刊名:Advanced Drug Delivery Reviews
出版年:2016
2.
Activation of multiple chemotherapeutic prodrugs by the natural enzymolome of tumour-localised probiotic bacteria
作者:
Panos Lehouritis
a
;
1
;
Michael Stanton
a
;
1
;
Florence O. McCarthy
b
;
Matthieu Jeavons
a
;
Mark Tangney
a
;
m.tangney@ucc.ie" class="auth_mail" title="E-mail the corresponding author
关键词:
Cancer
;
Therapy
;
Targeting
;
Chemotherapy
;
GDEPT
刊名:Journal of Controlled Release
出版年:2016
3.
Engineered mesenchymal stem cells as vectors in a suicide gene therapy against preclinical murine models for solid tumors
作者:
Ikrame Amara
a
;
Elodie Pramil
a
;
Catherine Senamaud-Beaufort
a
;
Audrey Devillers
a
;
Rodney Macedo
b
;
Gé
;
raldine Lescaille
b
;
Johanne Seguin
c
;
Eric Tartour
d
;
Franç
;
ois M. Lemoine
b
;
Philippe Beaune
a
;
Isabelle de Waziers
a
;
isabelle.waziers@parisdescartes.fr" class="auth_mail" title="E-mail the corresponding author
关键词:
Cyclophosphamide
;
Cytochrome P450 2B6 (CYP2B6)
;
Therapeutic stem cells
;
Preclinical models
;
Immune response
刊名:Journal of Controlled Release
出版年:2016
4.
Local bystander effect induces dormancy in human medullary thyroid carcinoma model in vivo
作者:
Lucia Kucerova
a
;
exonkuce@savba.sk
;
Lucia Feketeova
b
;
Miroslava Matuskova
a
;
Zuzana Kozovska
a
;
Pavol Janega
b
;
c
;
Pavel Babal
b
;
Martina Poturnajova
a
关键词:
Human medullary thyroid carcinoma
;
Gene-directed enzyme/prodrug therapy
;
Fusion yeast cytosine deaminase
;
5-Fluorocytosine
;
Bystander effect
刊名:Cancer Letters
出版年:2013
5.
Creation and screening of a multi-family bacterial oxidoreductase library to discover novel nitroreductases that efficiently activate the bioreductive prodrugs CB1954 and PR-104A
作者:
Gareth A. Prosser
a
;
Janine N. Copp
a
;
Alexandra M. Mowday
b
;
Christopher P. Guise
b
;
Sophie P. Syddall
b
;
Elsie M. Williams
a
;
Claire N. Horvat
a
;
Pearl M. Swe
a
;
Amir Ashoorzadeh
b
;
c
;
William A. Denny
b
;
c
;
Jeff B. Smaill
b
;
c
;
Adam V. Patterson
b
;
c
;
David F. Ackerley
a
;
c
;
d
;
david.ackerley@vuw.ac.nz
关键词:
CB1954
;
PR-104
;
Nitroreductase
;
Gene therapy
;
Nitroaromatic prodrug
;
SOS chromotest
刊名:Biochemical Pharmacology
出版年:2013
6.
Clinical potential of gene-directed enzyme prodrug therapy to improve radiation therapy in prostate cancer patients
作者:
Alice
;
Vajda
a
;
;
vajdaa@tcd.ie
;
Laure
;
Marignol
b
;
;
f
;
;
marignol@tcd.ie
;
Ruth
;
Foley
a
;
;
g
;
;
ruth.foley@tcd.ie
;
Thomas H.
;
Lynch
c
;
;
h
;
;
tlynch@stjames.ie
;
Mark
;
Lawler
d
;
;
i
;
;
mplawler@tcd.ie
;
Donal
;
Hollywood
e
;
;
j
;
;
dhlywood@tcd.ie
关键词:
Gene-directed enzyme prodrug therapy
;
GDEPT
;
Radiation therapy
;
Prostate cancer
刊名:Cancer Treatment Reviews
出版年:2011
7.
The novel hypoxic cytotoxin, TX-2098 has antitumor effect in pancreatic cancer; possible mechanism through inhibiting VEGF and hypoxia inducible factor-1¦Á targeted gene expression
作者:
Kotaro Miyake
a
;
hif.panc@gmail.com
;
Masanori Nishioka
a
;
Satoru Imura
a
;
Erdenebulgan Batmunkh
a
;
Yoshihiro Uto
b
;
Hideko Nagasawa
c
;
Hitoshi Hori
b
;
Mitsuo Shimada
a
关键词:
TPZ
;
Tirapazamine
;
HIF-1
;
hypoxia inducible factor-1
;
VEGF
;
vascular endothelial growth factor
;
GLUT1
;
glucose transporter 1
;
ELISA
;
enzyme-linked immunosorbent
;
EPO
;
erythropoietin
;
GPI
;
glucose phosphate isomerase
;
GDEPT
;
gene-directed enzyme prodrug th
刊名:Experimental Cell Research
出版年:2012
8.
Enhanced cytotoxicity with a novel system combining the paclitaxel-2′-ethylcarbonate prodrug and an HSV amplicon with an attenuated replication-competent virus, HF10 as a helper virus
作者:
Daisuke Ishida
;
Akihiro Nawa
;
Tadatoshi Tanino
;
Fumi Goshima
;
Chen Hong Luo
;
Masahiro Iwaki
;
Hiroaki Kajiyama
;
Kiyosumi Shibata
;
Eiko Yamamoto
;
Kazuhiko Ino
;
Tatsuya Tsurumi
;
Yukihiro Nishiyama
;
Fumit
关键词:
Oncolytic virus HSV-1 HF10
;
Gene directed enzyme prodrug therapy (
GDEPT
)
;
HSV amplicon
;
Carboxylesterase (CES)
;
Paclitaxel-2′
;
-ethylcarbonate prodrug (TAX-2′
;
-Et)
刊名:Cancer Letters
出版年:2010
9.
Discovery and evaluation of Escherichia coli nitroreductases that activate the anti-cancer prodrug CB1954
作者:
G.A. Prosser
;
J.N. Copp
;
S.P. Syddall
;
E.M. Williams
;
J.B. Smaill
;
W.R. Wilson
;
A.V. Patterson
;
D.F. Ackerley
关键词:
CB1954
;
Nitroreductase
;
SOS chromotest
;
GDEPT
;
Nitroaromatic prodrug
刊名:Biochemical Pharmacology
出版年:2010
10.
In vivo imaging of DNA lipid nanocapsules after systemic administration in a melanoma mouse model
作者:
Stephanie David
a
;
b
;
c
;
Nathalie Carmoy
d
;
Pauline Resnier
a
;
b
;
Caroline Denis
d
;
Laurent Misery
e
;
Bruno Pitard
c
;
Jean-Pierre Benoit
a
;
b
;
Catherine Passirani
a
;
b
;
catherine.passirani@univ-angers.fr
;
Tristan Montier
d
;
Tristan.Montier@univ-brest.fr
关键词:
Skin cancer
;
DNA LNCs
;
Real-time imaging
;
pHSV-tk
;
Ganciclovir
;
Intravenous injection
刊名:International Journal of Pharmaceutics
出版年:2012
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