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内部出版物
在“
Elsevier电子期刊
”中,
命中:
51
条,耗时:小于0.01 秒
1.
Cross-talk between autophagy and KLF2 determines endothelial cell phenotype and microvascular function in acute liver injury
作者:
Sergi Guixé
;
-Muntet
1
;
Fernanda Cristina de Mesquita
1
;
2
;
Sergi Vila
1
;
Virginia Herná
;
ndez-Gea
1
;
Carmen Peralta
3
;
Juan Carlos Garcí
;
a-Pagá
;
n
1
;
Jaime Bosch
1
;
Jordi Gracia-Sancho
1
;
jordi.gracia@idibaps.org
关键词:
Statins
;
Simvastatin
;
Ischemia/reperfusion
;
LSEC
;
HUVEC
;
Rab7
;
Rac1
刊名:Journal of Hepatology
出版年:2017
2.
Astrocyte
GGTI
-mediated Rac1 prenylation upregulates NF-κB expression and promotes neuronal apoptosis following hypoxia/ischemia
作者:
Shangfeng Gao
a
;
b
;
1
;
Jianbing Mo
c
;
1
;
Long Chen
c
;
1
;
Yan Wang
b
;
Xueqiang Mao
c
;
Yi Shi
c
;
Xianfeng Zhang
c
;
Rutong Yu
a
;
b
;
yu.rutong@163.com" class="auth_mail" title="E-mail the corresponding author
;
Xiuping Zhou
a
;
b
;
xpzhou@xzmc.edu.cn" class="auth_mail" title="E-mail the corresponding author
关键词:
Geranylgeranyltransferase I
;
Rac1
;
NF-κB
;
Brain ischemia
;
Stroke
;
Apoptosis
刊名:Neuropharmacology
出版年:2016
3.
Potential of tocotrienols in the prevention and therapy of Alzheimer's disease
作者:
Weiming Xia
a
;
Weiming.xia@va.gov" class="auth_mail" title="E-mail the corresponding author
;
Huanbiao Mo
b
;
c
;
hmo@gsu.edu" class="auth_mail" title="E-mail the corresponding author
关键词:
Aβ
;
amyloid β protein
;
AD
;
Alzheimer's disease
;
ApoE
;
apolipoprotein E
;
APP
;
amyloid precursor protein
;
BACE1
;
β-secretase
;
CI
;
confidence interval
;
CN
;
cognitively normal
;
FPP
;
farnesyl pyrophosphate
;
FTI
;
farnesyl transferase inhibitor
;
GGPP
;
geranylgeranyl pyrophosphate
;
GGTI
;
geranylgeranyl transferase inhibitor
;
GRAS
;
Generally Recognized As Safe
;
HMG CoA
;
3-hydroxy-3-methylglutaryl coenzyme A
;
LDLR
;
low-density lipoprotein receptor
;
LLA
;
lipid-lowering agent
;
LPS
;
lipopolysaccharide
;
MCI
刊名:Journal of Nutritional Biochemistry
出版年:2016
4.
Simvastatin inhibits protein isoprenylation in the brain
作者:
Stephen M. Ostrowski
a
;
Kachael Johnson
b
;
c
;
Matthew Siefert
c
;
Sam Shank
d
;
Luigi Sironi
e
;
Benjamin Wolozin
f
;
Gary E. Landreth
a
;
Assem G. Ziady
b
;
c
;
d
;
assem.ziady@cchmc.org" class="auth_mail" title="E-mail the corresponding author
关键词:
2D
;
two-dimensional
;
AD
;
Alzheimer&rsquo
;
s disease
;
APP
;
amyloid precursor protein
;
FPP
;
farnesyl pyrophosphate
;
GGPP
;
geranylgeranyl pyrophosphate
;
GGT
;
geranylgeranyl transferase
;
GGTI
;
GGT inhibitor
;
HEPES
;
4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid
;
HMG-CoA
;
3-hydroxy-3-methylglutaryl-coenzyme A
;
Icmt
;
isoprenylcysteine-O-c transferase
;
pI
;
isoelectric point
;
SDS&ndash
;
PAGE
;
sodium dodecyl sulfate polyacrylamide gel electrophoresis
刊名:Neuroscience
出版年:2016
5.
Pharmacological modulation of oncogenic Ras by natural products and their derivatives: Renewed hope in the discovery of novel anti-Ras drugs
作者:
Shun Ying Quah
a
;
1
;
Michelle Siying Tan
a
;
1
;
Yuan Han Teh
a
;
1
;
Johnson Stanslas
a
;
b
;
rcxjs@upm.edu.my" class="auth_mail" title="E-mail the corresponding author
;
jstanslas@yahoo.co.uk" class="auth_mail" title="E-mail the corresponding author
关键词:
AGP
;
Andrographolide
;
APT1
;
Acyl protein thioesterase 1
;
COX-2
;
cyclooxygenase-2
;
DPI
;
Dual prenylation inhibitor
;
ERK
;
Extracellular signal-regulated kinase
;
FBDD
;
Fragment-based drug discovery
;
FTase
;
Farnesyltransferase
;
FTIs
;
Farnesyltransferase inhibitors
;
G12
;
Glycine-12
;
G13
;
Glycine-13
;
Q61
;
Glutamine-61
;
GAP
;
GTPase-activating protein
;
GDP
;
Guanosine diphosphate
;
GEF
;
Guanine nucleotide exchange factor
;
GGTase I
;
Geranylgeranyltransferase I
;
GGTI
;
Geranylgeranyltransferase inhibitor
;
GT
刊名:Pharmacology and Therapeutics
出版年:2016
6.
Statin-mediated inhibition of cholesterol synthesis induces cytoprotective autophagy in human leukemic cells
作者:
Urosh Vilimanovich
a
;
1
;
Mihajlo Bosnjak
a
;
1
;
Andrija Bogdanovic
b
;
Ivanka Markovic
c
;
Aleksandra Isakovic
c
;
Tamara Kravic-Stevovic
a
;
Aleksandar Mircic
a
;
Vladimir Trajkovic
d
;
vtrajkovic@med.bg.ac.rs" class="auth_mail" title="E-mail the corresponding author
;
Vladimir Bumbasirevic
a
;
v_bumbasirevic@med.bg.ac.rs" class="auth_mail" title="E-mail the corresponding author
关键词:
Simvastatin (PubChem CID
;
54454)
;
Lovastatin (PubChem CID
;
53232)
;
Atorvastatin (PubChem CID
;
60823)
;
FTI-227 (PubChem CID
;
3005532)
;
GGTI
-2133 (PubChem CID
;
16078972)
;
Mevalonate (PubChem CID
;
439230)
;
Squalene (PubChem CID
;
25244109)
;
Farnesylpyrophosphate (PubChem CID
;
44134714)
;
Geranylgeranylpyrophosphate (PubChem CID
;
44134732)
;
Ro 48-8071 (PubChem CID
;
1949)
刊名:European Journal of Pharmacology
出版年:2015
7.
Protein prenylation in islet β-cell function in health and diabetes: Putting the pieces of the puzzle together
作者:
Anjaneyulu Kowluru
a
;
b
;
akowluru@med.wayne.edu" class="auth_mail" title="E-mail the corresponding author
;
Renu A. Kowluru
c
关键词:
ERK1/2
;
extracellular signal-related kinase 1/2
;
Fpp
;
farnesyl pyrophosphate
;
FTase
;
farnesyl transferase
;
FTase/GGTase-α
;
common α-subunit of FTase and GGTase
;
FTI
;
farnesyl transferase inhibitor
;
GGpp
;
geranylgeranyl pyrophosphate
;
GGTase-I
;
geranylgeranyl transferase-I
;
GGTase-II
;
geranylgeranyl transferase-II
;
GGTI
;
geranylgeranyl transferase inhibitor
;
GSIS
;
glucose-stimulated insulin secretion
;
GTP
;
guanosine triphosphate
;
G proteins
;
GTP-binding proteins
;
ICMT
;
isoprenylcysteine methyl tr
刊名:Biochemical Pharmacology
出版年:2015
8.
Pharmacological modulation of geranylgeranyltransferase and farnesyltransferase attenuates opioid withdrawal in?vivo and in?vitro
作者:
Ashish K. Rehni
ashishkrehni@gmail.com
;
Thakur Gurjeet Singh
;
gurjeetthakur@gmail.com
关键词:
Morphine dependence
;
Withdrawal syndrome
;
GGTI
-2133
;
FTI-276
;
Geranylgeranyl transferase
;
Farnesyltransferase
刊名:Neuropharmacology
出版年:2013
9.
Phagocyte-like NADPH oxidase [Nox2] in cellular dysfunction in models of glucolipotoxicity and diabetes
作者:
Anjaneyulu Kowluru
a
;
b
;
akowluru@med.wayne.edu" class="auth_mail
;
Renu A. Kowluru
c
;
d
关键词:
2-BP
;
2-bromopalmitate
;
BRECs
;
bovine retinal endothelial cells
;
Cer
;
ceramide
;
CER
;
cerulenin
;
DPI
;
diphenyleneiodonium
;
ER stress
;
endoplasmic reticulum stress
;
FTase
;
farnesyltransferase
;
FTI
;
farnesyltransferase inhibitor
;
GEFs
;
guanine nucleotide exchange factors
;
GGTase
;
geranylgeranyltransferase
;
GGTI
;
geranylgeranyltransferase inhibitor
;
GSIS
;
glucose-stimulated insulin secretion
;
IFN纬
;
interferon-纬
;
IL-1尾
;
interleukin-1尾
;
iNOS
;
inducible nitric oxide synthase
;
NO
;
nitric oxide
;
Nox2
刊名:Biochemical Pharmacology
出版年:1 April, 2014
10.
Involvement of protein isoprenylation in neuropathic pain induced by sciatic nerve injury in mice
作者:
Masahiro Ohsawa
a
;
b
;
ohsawa@phar.nagoya-cu.ac.jp" class="auth_mail
;
Junpei Mutoh
a
;
Shohei Yamamoto
b
;
Hiroaki Hisa
a
关键词:
Hyperalgesia
;
Allodynia
;
Protein isoprenylation
;
MARCKS protein
刊名:Neuroscience Letters
出版年:3 April, 2014
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