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CNKI学位论文(21)
知网期刊论文(1)
在“
Elsevier电子期刊
”中,
命中:
16
条,耗时:小于0.01 秒
在所有数据库中总计命中:
22
条
1.
Balancing Inflammation: Computational Design of Small-Molecule Toll-like Receptor Modulators
作者:
Manuela S. Murgueitio
1
;
Christin Rakers
1
;
Anne Frank
1
;
Gerhard
Wolber
1
;
gerhard
.
wolber
@fu-berlin.de
关键词:
Toll-like receptor
;
virtual screening
;
drug design
;
inflammation
刊名:Trends in Pharmacological Sciences
出版年:2017
2.
More than a look into a crystal ball: protein structure elucidation guided by molecular dynamics simulations
作者:
Marcel Bermudez
;
m.bermudez@fu-berlin.de" class="auth_mail" title="E-mail the corresponding author
;
Jeremie Mortier
;
Christin Rakers
;
Dominique Sydow
;
Gerhard
Wolber
刊名:Drug Discovery Today
出版年:2016
3.
From carbohydrates to drug-like fragments: Rational development of novel 伪-amylase inhibitors
作者:
Jamil Al-Asri
a
;
Erika Fazekas
b
;
Gá
;
bor Lehoczki
b
;
Andrej Perdih
c
;
Cornelia Gö
;
rick
a
;
Matthias F. Melzig
a
;
Gyö
;
ngyi Gyé
;
má
;
nt
b
;
Gerhard
Wolber
a
;
gerhard
.
wolber
@fu-berlin.de" class="auth_mail" title="E-mail the corresponding author
;
Jé
;
ré
;
mie Mortier
a
;
jeremie.mortier@fu-berlin.de" class="auth_mail" title="E-mail the corresponding author
关键词:
伪-Amylase inhibition
;
Fragment-based drug design
;
Virtual screening
;
Pharmacophore model
;
Hyperglycaemia
;
Obesity
;
Type II diabetes
刊名:Bioorganic & Medicinal Chemistry
出版年:2015
4.
Synthesis, biological activity and structure-activity relationships of new benzoic acid-based protein tyrosine phosphatase inhibitors endowed with insulinomimetic effects in mouse C2C12 skeletal muscle cells
作者:
Rosaria Ottan脿
;
Rosanna Maccari
;
J茅r茅mie Mortier
;
Anna Caselli
;
Simona Amuso
;
Guido Camici
;
Archimede Rotondo
;
Gerhard
Wolber
;
Paolo Paoli
关键词:
Protein tyrosine phosphatases
;
Enzyme inhibitors
;
Insulinomimetic effects
;
Molecular docking
;
5-Arylidene-4-thiazolidinone derivatives
;
4-[(5-Arylidene-4-oxo-2-phenylimino/oxothiazolidin-3-yl)methyl]benzoic acids
刊名:European Journal of Medicinal Chemistry
出版年:7 January, 2014
5.
Design, synthesis and structure-activity relationship of novel quinoxaline derivatives as cancer chemopreventive agent by inhibition of tyrosine kinase receptor
作者:
Shadia A. Galal
;
Ahmed S. Abdelsamie
;
Salwa M. Soliman
;
Jeremie Mortier
;
Gerhard
Wolber
;
Mamdouh M. Ali
;
Harukuni Tokuda
;
Nobutaka Suzuki
;
Akira Lida
;
Raghda A. Ramadan
;
Hoda I. El Diwani
关键词:
Synthesis
;
Quinoxalines
;
Epstein&ndash
;
Barr virus
;
Cancer chemopreventive activity
;
Docking
;
Protein tyrosine kinase
刊名:European Journal of Medicinal Chemistry
出版年:November, 2013
6.
In silico virtual screening approaches for anti-viral drug discovery
作者:
Manuela S. Murgueitio
;
Marcel Bermudez
;
Jé
;
ré
;
mie Mortier
;
Gerhard
Wolber
;
gerhard
.
wolber
@fu-berlin.de
刊名:Drug Discovery Today: Technologies
出版年:2012
7.
Discovery of a novel IKK-β inhibitor by ligand-based virtual screening techniques
作者:
Stefan M. Noha
;
Atanas G. Atanasov
;
Daniela Schuster
;
Patrick Markt
;
Nanang Fakhrudin
;
Elke H. Heiss
;
Olivia Schrammel
;
Judith M. Rollinger
;
Hermann Stuppner
;
Verena M. Dirsch
;
Gerhard
Wolber
关键词:
I kappa B kinase β
;
IKK-β
;
Virtual screening
;
Pharmacophore
;
Shape-based screening
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2011
8.
11β-Hydroxysteroid dehydrogenase 1 inhibiting constituents from Eriobotrya japonica revealed by bioactivity-guided isolation and computational approaches
作者:
Judith M. Rollinger
;
Denise V. Kratschmar
;
Daniela Schuster
;
Petra H. Pfisterer
;
Christel Gumy
;
Evelyne M. Aubry
;
Sarah Br
;
stö
;
tter
;
Hermann Stuppner
;
Gerhard
Wolber
;
Alex Odermatt
关键词:
Eriobotrya japonica
;
11β
;
-HSD1
;
Diabetes
;
Glucocorticoid receptor
;
Metabolic syndrome
刊名:Bioorganic and Medicinal Chemistry
出版年:2010
9.
The UV-filter benzophenone-1 inhibits 17β-hydroxysteroid dehydrogenase type 3: Virtual screening as a strategy to identify potential endocrine disrupting chemicals
作者:
Lyubomir G. Nashev
;
Daniela Schuster
;
Christian Laggner
;
Seloni Sodha
;
Thierry Langer
;
Gerhard
Wolber
;
Alex Odermatt
关键词:
17β
;
-Hydroxysteroid dehydrogenase
;
Androgen
;
Testosterone
;
Endocrine disruptor
;
Pharmacophore
;
Virtual screening
;
UV-filter
刊名:Biochemical Pharmacology
出版年:2010
10.
Characterization of new PPARγ agonists: Benzimidazole derivatives—importance of positions 5 and 6, and computational studies on the binding mode
作者:
Matthias Goebel
;
Gerhard
Wolber
;
Patrick Markt
;
Bart Staels
;
Thomas Unger
;
Ulrich Kintscher
;
Ronald Gust
关键词:
Benzimidazole derivatives
;
Partial agonism
;
Selective PPARγ
;
modulators
;
Structure–
;
activity relationship
;
Molecular modeling
刊名:Bioorganic and Medicinal Chemistry
出版年:2010
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