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在“Elsevier电子期刊”中，命中：101条，耗时：0.0339801 秒

在所有数据库中总计命中：790条

1.Discovery of indazole ethers as novel, potent, non-steroidal glucocorticoid receptor modulators

作者：Martin Hemmerling^a ; ^{martin.hemmerling@astrazeneca.com" class="auth_mail" title="E-mail the corresponding author} ; Karl Edman^b ; Matti Lepistö ; ^a ; Anders Eriksson^a ; Svetlana Ivanova^c ; Jan Dahmé ; n^c ; Hartmut Rehwinkel^d ; Markus Berger^d ; Ramon Hendrickx^a ; Matthew Dearman^a ; Tina Jellesmark Jensen^a ; Lisa Wissler^b ; Thomas Hansson^a

关键词：Non-steroidal glucocorticoid ; Glucocorticoid receptor modulators ; Indazoles ; Anti-inflammatory activity

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

2.New selective glucocorticoid receptor modulators reverse amyloid-β peptide-induced hippocampus toxicity

作者：Fanny Pineau^a ; ^b ; ^c ; Geoffrey Canet^a ; ^b ; ^c ; Catherine Desrumaux^a ; ^b ; ^c ; Hazel Hunt^d ; Nathalie Chevallier^a ; ^b ; ^c ; Matthias Ollivier^a ; ^b ; ^c ; Joseph K. Belanoff^d ; Laurent Givalois^a ; ^b ; ^c ; ^{lgivalois@univ-montp2.fr" class="auth_mail" title="E-mail the corresponding author}

关键词：Alzheimer's disease ; Glucocorticoid receptors ; HPA axis ; Amyloid-β peptide ; Hippocampus ; Selective GR modulator ; Aβ25&ndash ; 35 peptide ; Rat

刊名：Neurobiology of Aging

出版年：2016

3.Activation of the Glucocorticoid Receptor in Acute Inflammation: the SEDIGRAM Concept

作者：Karolien De Bosscher¹ ; Ilse M. Beck² ; Dariusz Ratman¹ ; Wim Vanden Berghe³ ; Claude Libert⁴ ; ^{Claude.Libert@irc.vib-ugent.be" class="auth_mail" title="E-mail the corresponding author}

刊名：Trends in Pharmacological Sciences

出版年：2016

4.Small-molecule modulators of PXR and CAR

作者：Sergio C. Chai¹ ; Milu T. Cherian¹ ; Yue-Ming Wang¹ ; Taosheng Chen ; ^{Taosheng.Chen@stjude.org" class="auth_mail" title="E-mail the corresponding author}

关键词：AF-2 ; activation function 2 ; CAR ; constitutive androstane receptor ; CYP ; cytochrome P450 ; DBD ; DNA-binding domain ; DDI ; drug&ndash ; drug interactions ; DEHP ; di(2-ethylhexyl) phthalate ; DILI ; drug-induced liver injury ; DR4 ; direct repeat separated by 4 nucleotides ; DSS ; dextran sulfate sodium ; EE2 ; 17α-ethinylestradiol ; EGFR ; EGF receptor ; G6Pase ; glucose-6-phosphatase ; GR ; glucocorticoid receptor ; GST ; glutathione S-transferase ; HDL ; high-density lipoprotein ; HNF4α ; hepatocyte nuclear factor 4 al

刊名：Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms

出版年：2016

5.The discovery of potent and selective non-steroidal glucocorticoid receptor modulators, suitable for inhalation

作者：Karl Edman^a ; Ragnhild Ahlgren^b ; Malena Bengtsson^b ; Hå ; kan Bladh^b ; Stefan Bä ; ckströ ; m^a ; Jan Dahmé ; n^b ; Krister Henriksson^b ; Per Hillertz^a ; Vijakumar Hulikal^b ; Anders Jerre^b ; Liz Kinchin^b ; Charlotte Kå ; se^b ; Matti Lepistö ; ^c ; Irene Mile^b ; Stinabritt Nilsson^b ; Amir Smailagic^c ; John Taylor^c ; Ann Tjö ; rnebo^b ; Lisa Wissler^a ; Thomas Hansson^c ; ^{thomas.g.hansson@astrazeneca.com" class="auth_mail}

关键词：Glucocorticoid receptor ; Non-steroidal selective glucocorticoid receptor modulators ; Inhalation ; Indazoles

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：1 June 2014

6.T25: Selective glucocorticoid receptor agonists as novel anti-cancer agents

作者：E. Lesovaya^a ; ; L. Tilova^a ; O. Zadorozhnaya^a ; A. Savinkova^a ; K. Kirsanov^a ; A. Ogloblina^a ; G. Belitsky^a ; G. Baida^b ; I. Budunova^b ; M. Yakubovskaya^a

刊名：European Journal of Cancer Supplements

出版年：2015

7.Molecular docking revealed potential disruptors of glucocorticoid receptor-dependent reporter gene expression

作者：Katra Kol&scaron ; ek ; Martina Gobec ; Irena Mlinari膷 Ra&scaron ; 膷an ; Marija Sollner Dolenc ; ^{marija.sollner@ffa.uni-lj.si" class="auth_mail}

关键词：Glucocorticoid receptor ; Molecular docking ; Phthalates ; Pyrethroid insecticide ; Bisphenols

刊名：Toxicology Letters

出版年：21 April, 2014

8.Heterocyclic glucocorticoid receptor modulators with a 2,2-dimethyl-3-phenyl-N-(thiazol or thiadiazol-2-yl)propanamide core

作者：Hai-Yun Xiao ; Dauh-Rurng Wu ; James E. Sheppeck II ; Sium F. Habte ; Mark D. Cunningham ; John E. Somerville ; Joel C. Barrish ; Steven G. Nadler ; T.G. Murali Dhar

关键词：Glucocorticoid receptor ; Non-steroidal glucocorticoid receptor agonists ; Dissociated steroids ; Transrepression ; Transactivation

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：2013

9.Preclinical pharmacology of FL442, a novel nonsteroidal androgen receptor modulator

作者：Pekka K. Poutiainen^a ; Tuulia Huhtala^b ; ^c ; ¹ ; Tiina Jä ; ä ; skelä ; inen^d ; ^e ; Aleksanteri Petsalo^a ; ^f ; Jenni Kü ; blbeck^a ; Sanna Kaikkonen^d ; Jorma J. Palvimo^d ; Hannu Raunio^a ; Ale Nä ; rvä ; nen^a ; ^c ; Mikael Perä ; kylä ; ^d ; ² ; Risto O. Juvonen^a ; Paavo Honkakoski^a ; Reino Laatikainen^a ; Juha T. Pulkkinen^a ; ^{juha.t.pulkkinen@uef.fi" class="auth_mail}

关键词：ADT ; androgen-deprivation therapy ; AF2 ; activation function 2 ; AhR ; aryl hydrocarbon receptor ; AR ; androgen receptor ; Bic ; bicalutamide ; CAR ; constitutive androstane receptor ; COS-1 ; African green monkey kidney cells ; CRPC ; castration resistant prostate cancer ; DHT ; 5伪-dihydrotestosterone ; DMEM ; Dulbecco&lsquo ; s modified Eagle medium ; ER ; estrogen receptor ; FBS ; fetal bovine serum ; FLuc ; firefly luciferase ; GAPDH ; glyceraldehyde 3-phosphate dehydrogenase ; GR ; glucocorticoid receptor ; hAR ; human

刊名：Molecular and Cellular Endocrinology

出版年：25 April, 2014

10.Function-regulating pharmacophores in a sulfonamide class of glucocorticoid receptor agonists

作者：Daniel Kuzmich ; J枚rg Bentzien ; Raj Betageri ; Darren DiSalvo ; Tazmeen Fadra-Khan ; Christian Harcken ; Alison Kukulka ; Gerald Nabozny ; Richard Nelson ; Edward Pack ; Donald Souza ; David Thomson

关键词：Glucocorticoids ; Glucocorticoid receptor ; Nuclear hormone receptor ; Mineralocorticoid receptor ; Progesterone receptor ; Inflammation ; Collagen induced arthritis ; Arylsulfonamide

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：15 December, 2013

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