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CNKI学位论文(119)

知网期刊论文(212)

在“Elsevier电子期刊”中，命中：97条，耗时：0.0159921 秒

在所有数据库中总计命中：331条

1.Development and validation of a simple and robust HPLC method with UV detection for quantification of the hepatitis C virus inhibitor daclatasvir in human plasma

作者：Giulio Nannetti^a ; Lorenzo Messa^a ; Marta Celegato^a ; Silvana Pagni^a ; ^b ; Monica Basso^a ; ^b ; Saverio G. Parisi^a ; ^b ; Giorgio Palù ; ^a ; ^b ; ¹ ; Arianna Loregian^a ; ^b ; ¹ ; ^{arianna.loregian@unipd.it}

关键词：Daclatasvir ; BMS-790052 ; HCV NS5A inhibitor ; Solid-phase extraction ; HPLC-UV ; Therapeutic drug monitoring

刊名：Journal of Pharmaceutical and Biomedical Analysis

出版年：2017

2.New potent biaryl sulfate-based hepatitis C virus inhibitors

作者：Youngsu You^a ; ¹ ; Hee Sun Kim^b ; ¹ ; Il Hak Bae^a ; Seung Gi Lee^c ; Min Hyeok Jee^c ; Gyochang Keum^d ; Sung Key Jang^c ; ^{sungkey@postech.ac.kr} ; B. Moon Kim^a ; ^{kimbm@snu.ac.kr}

关键词：HCV ; NS5A inhibitor ; Biaryl sulfate ; Structure-activity relationship

刊名：European Journal of Medicinal Chemistry

出版年：2017

3.Regulatory Analysis of Effects of Hepatitis C Virus NS5A Polymorphisms on Efficacy of Elbasvir and Grazoprevir

作者：Takashi E. Komatsu¹ ; ^{takashi.komatsu@fda.hhs.gov} ; Sarita Boyd¹ ; Adam Sherwat¹ ; LaRee Tracy² ; Lisa K. Naeger¹ ; Julian J. O&rsquo ; Rear¹ ; Patrick R. Harrington¹ ; ^{patrick.harrington@fda.hhs.gov}

关键词：DAA ; Replication ; FDA ; Post-Hoc Analysis

刊名：Gastroenterology

出版年：2017

4.Effectiveness of Elbasvir and Grazoprevir Combination, With or Without Ribavirin, for Treatment-Experienced Patients With Chronic Hepatitis C Infection

作者：Paul Kwo¹ ; ^{pkwo@stanford.edu} ; Edward J. Gane² ; Cheng-Yuan Peng³ ; Brian Pearlman⁴ ; John M. Vierling⁵ ; Lawrence Serfaty⁶ ; Maria Buti⁷ ; Stephen Shafran⁸ ; Paul Stryszak⁹ ; Li Lin⁹ ; Jacqueline Gress⁹ ; Stuart Black⁹ ; Frank J. Dutko⁹ ; Michael Robertson⁹ ; Janice Wahl⁹ ; Lisa Lupinacci⁹ ; Eliav Barr⁹ ; Barbara Haber⁹

关键词：Hepatitis C ; Randomized ; Therapy ; C-EDGE Treatment-Experienced

刊名：Gastroenterology

出版年：2017

5.Discovery of fluorobenzimidazole HCV NS5A inhibitors

作者：John T. Randolph ; Charles A. Flentge ; Pamela Donner ; Todd W. Rockway ; Sachin V. Patel ; Lissa Nelson ; Douglas K. Hutchinson ; Rubina Mondal ; Neeta Mistry ; Thomas Reisch ; Tatyana Dekhtyar ; Preethi Krishnan ; Tami Pilot-Matias ; Deanne F. Stolarik ; David W.A. Beno ; Rolf Wagner ; Clarence Maring ; Warren M. Kati

关键词：HCV ; NS5A inhibitor ; Antiviral

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

6.Discovery of ravidasvir (PPI-668) as a potent pan-genotypic HCV NS5A inhibitor

作者：Min Zhong ; ^&dagger ; ; ^{mzhong@myokardia.com" class="auth_mail" title="E-mail the corresponding author} ; Eric Peng ; Ningwu Huang ; Qi Huang ; Anja Huq ; Meiyen Lau ; Richard Colonno ; Leping Li ; ^&Dagger ; ; ^{leping@assemblybio.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Hepatitis C virus ; NS5A inhibitor ; Benzimidazole&ndash ; naphthylene&ndash ; imidazole derivatives ; Ravidasvir ; PPI-668

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

7.Alternative core development around the tetracyclic indole class of HCV NS5A inhibitors

作者：Ling Tong^a ; ; Wensheng Yu^a ; Craig A. Coburn^a ; Peter T. Meinke^a ; Anilkumar G. Nair^a ; Michael P. Dwyer^a ; Lei Chen^a ; Oleg Selyutin^a ; Stuart B. Rosenblum^a ; Yueheng Jiang^a ; James Fells^a ; Bin Hu^b ; Bin Zhong^b ; Richard M. Soll^b ; Rong Liu^a ; Sony Agrawal^a ; Ellen Xia^a ; Ying Zhai^a ; Rong Kong^a ; Paul Ingravallo^a ; Amin Nomeir^a ; Ernest Asante-Appiah^a ; Joseph A. Kozlowski^a

关键词：HCV NS5A inhibitor ; Elbasvir ; MK-8742 ; Direct-acting antiviral agents ; DAA ; HCV infection treatment ; Tetracyclic core

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

8.Alkyl substituted aminal derivatives of HCV NS5A inhibitor MK-8742

作者：Wensheng Yu^a ; ^{wensheng.yu@merck.com" class="auth_mail" title="E-mail the corresponding author} ; Craig A. Coburn^b ; Anilkumar G. Nair^a ; Michael Wong^a ; Ling Tong^a ; Michael P. Dwyer^a ; Bin Hu^c ; Bin Zhong^c ; Jinglai Hao^c ; De-Yi Yang^a ; Oleg Selyutin^a ; Yueheng Jiang^a ; Stuart B. Rosenblum^a ; Seong Heon Kim^a ; Brian J. Lavey^a ; Guowei Zhou^a ; Razia Rizvi^a ; Bandarpalle B. Shankar^a ; Qingbei Zeng^a ; Lei Chen^a ; Sony Agrawal^d ; Donna Carr^d ; Laura Rokosz^d ; Rong Liu^e ; Stephanie Curry^e ; Patricia McMonagle^e ; Paul Ingravallo^e ; Fred Lahser^e ; Ernest Asante-Appiah^e ; Amin Nomeir^f ; Joseph A. Kozlowski^a

关键词：BVAZQCUMNICBAQ-PZHYSIFUSA-N ; CGWIQTMOZACRHO-JGWWVUOKSA-N ; PLGAPCRWWULNNY-QIKRQHTMSA-N ; HVQPLOYCSSNTLU-ZLRJGBHPSA-N ; XSZNVZHMIMRTSW-AVNCCPHYSA-N ; KSSPCKOUBGFLGY-AVNCCPHYSA-N ; ZTKDISPEEJLVLZ-DYSJQOLXSA-N ; ZHDQPFPOWUOIDN-LEIRQVFBSA-N ; WRCDRUFXYBYOMQ-MOKNKNHJSA-N ; NDPGCXHNKBEWGE-NPTDXBJXSA-N ; OULXSYATJCDLKS-ZLRJGBHPSA-N ; BWIDBJZHNXZZRR-SKFDGZKZSA-N ; QMWHDHATHSZAOV-MDHUNEKDSA-N ; AUOIUPIMBMLOIR-DCTIZDGDSA-N ; NPMMJCGMZQERJW-JYUYELIWSA-N ; PAYKQBIPPSKPSN-LCSZIOFPSA-N ; MCPQISFWVIDUMA-LTDGQNSRSA-N ; LOIPKGB

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

9.Aryl or heteroaryl substituted aminal derivatives of HCV NS5A inhibitor MK-8742

作者：Wensheng Yu^a ; ; Craig A. Coburn^b ; Anilkumar G. Nair^a ; Michael Wong^a ; Stuart B. Rosenblum^a ; Guowei Zhou^a ; Michael P. Dwyer^a ; Ling Tong^a ; Bin Hu^c ; Bin Zhong^c ; Jinglai Hao^c ; Tao Ji^c ; Shuai Zan^c ; Seong Heon Kim^a ; Qingbei Zeng^a ; Oleg Selyutin^a ; Lei Chen^a ; Frederic Masse^d ; Sony Agrawal^d ; Rong Liu^e ; Ellen Xia^d ; Ying Zhai^d ; Stephanie Curry^e ; Patricia McMonagle^e ; Paul Ingravallo^e ; Ernest Asante-Appiah^e ; Mingxiang Lin^f ; Joseph A. Kozlowski^a

关键词：XXMYVGBAHJZAHH-DBFVGOLASA-N ; FLDBOLOBRLMSHU-LEIRQVFBSA-N ; VLINDSPVYPOCKD-DYSJQOLXSA-N ; GHZSWSOYQIFBAA-HIIDTSOHSA-N ; VLKGLFRTXSAWLC-HIIDTSOHSA-N ; DDWRYTGXAPUCCU-MOKNKNHJSA-N ; IQYCGFUBAXSQGT-MOKNKNHJSA-N ; DVOCGCPQHPYVLQ-MOKNKNHJSA-N ; AYEKKEBXMVMQCW-NPTDXBJXSA-N ; MHRXLNLLUKFSPA-NPTDXBJXSA-N ; SQUFCGHNIRTTQO-VPQGWNJZSA-N ; KNLKVPVXRMGYFZ-VPQGWNJZSA-N ; UJXHOBOEBQXXDO-ZIEJMRAYSA-N ; IROXEJUPIAHIKR-ZIEJMRAYSA-N ; RHXGEOLLIYZLGW-RKUGBEGMSA-N ; IYLNUNSJACDBHO-NZRCMKGGSA-N ; GUDYLVLIGVZFHC-PFHKGJDSSA-N

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

10.Effectiveness of Ledipasvir-Sofosbuvir Combination in Patients With Hepatitis C Virus Infection and Factors Associated With Sustained Virologic Response

作者：Norah A. Terrault¹ ; ^{norah.terrault@ucsf.edu} ; Stefan Zeuzem² ; Adrian M. Di Bisceglie³ ; Joseph K. Lim⁴ ; Paul J. Pockros⁵ ; Lynn M. Frazier⁶ ; Alexander Kuo⁷ ; Anna S. Lok⁸ ; Mitchell L. Shiffman⁹ ; Ziv Ben Ari¹⁰ ; Lucy Akushevich¹¹ ; Monika Vainorius¹¹ ; Mark S. Sulkowski¹² ; Michael W. Fried¹¹ ; David R. Nelson¹³ ; for the HCV-TARGET Study GroupDavid R. Nelson ; Michael W. Fried

关键词：DAA ; NS5A Inhibitor ; NS5B Inhibitor ; Antiviral

刊名：Gastroenterology

出版年：2016

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