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在“Elsevier电子期刊”中，命中：121条，耗时：小于0.01 秒

在所有数据库中总计命中：3,500条

1.Trastuzumab Emtansine in HER2+ Recurrent Metastatic Non-Small-Cell Lung Cancer: Study Protocol

作者：Kadoaki Ohashi¹ ; ^{kohashi@cc.okayama-u.ac.jp} ; Katsuyuki Hotta² ; Taizo Hirata² ; Keisuke Aoe³ ; Toshiyuki Kozuki⁴ ; Kiichiro Ninomiya⁵ ; Hiroe Kayatani⁵ ; Hiroyuki Yanai⁶ ; Shinichi Toyooka⁷ ; Shiro Hinotsu² ; Minoru Takata⁸ ; Katsuyuki Kiura¹

关键词：HER2 amplification ; HER2 mutations ; HER2 over-expression ; NSCLC ; Trastuzumab emtansine

刊名：Clinical Lung Cancer

出版年：2017

2.Comprehensive genomic sequencing and the molecular profiles of clinically advanced breast cancer

作者：Jeffrey S. Ross¹ ; ² ; ^{jross@foundationmedicine.com} ; Laurie M. Gay¹

关键词：Next-generation sequencing ; comprehensive genomic profiling ; breast carcinoma ; ERBB2 ; HER2 ; triple-negative breast cancer ; tumour mutational burden ; clinically relevant genomic alterations

刊名：Pathology

出版年：2017

3.Frequent detection of PIK3CA mutations in single circulating tumor cells of patients suffering from HER2-negative metastatic breast cancer

作者：Christin Gasch^a ; ¹ ; ² ; Theresa Oldopp^a ; ¹ ; ³ ; Oliver Mauermann^a ; Tobias M. Gorges^a ; Antje Andreas^a ; Cornelia Coith^a ; Volkmar Mü ; ller^b ; Tanja Fehm^c ; Wolfgang Janni^d ; Klaus Pantel^a ; Sabine Riethdorf^a ; ^{s.riethdorf@uke.de" class="auth_mail" title="E-mail the corresponding author}

关键词：Metastatic breast cancer ; HER2 ; Circulating tumor cells ; PIK3CA

刊名：Molecular Oncology

出版年：2016

4.New insights on PI3K/AKT pathway alterations and clinical outcomes in breast cancer

作者：Sherry X. Yang^a ; ^{Sherry.Yang@nih.gov" class="auth_mail" title="E-mail the corresponding author} ; Eric Polley^b ; ¹ ; Stanley Lipkowitz^c

关键词：Breast cancer ; Chemotherapy ; HER2 ; Paclitaxel ; pAKT ; PIK3CA mutations

刊名：Cancer Treatment Reviews

出版年：2016

5.EGFR mutations in lung cancer: A morphological, immunohistochemical and molecular study of lung adenocarcinoma

作者：Montse Verdu^a ; ^b ; ^{mverdu@histopat.es" class="auth_mail" title="E-mail the corresponding author} ; Isabel Trias^a ; ^b ; ^c ; Ruth Roman^b ; Natalia Rodon^b ; Carme Pubill^a ; Miquel Calvo^d ; Beatriz Garcia-Pelaez^b ; Olga Diaz^b ; Xavier Puig^a ; ^b ; ^c

关键词：EGFR exon 19 deletion ; EGFR exon 21 L858R point mutation ; Lung adenocarcinoma ; Necrosis ; Immunohistochemistry

刊名：Revista Española de Patología

出版年：2016

6.Activation Mechanism of Oncogenic Deletion Mutations in BRAF, EGFR, and HER2

作者：Scott A. Foster¹ ; Daniel M. Whalen² ; Ayşegü ; l Ö ; zen³ ; ⁴ ; Matthew J. Wongchenko⁵ ; JianPing Yin² ; Ivana Yen¹ ; Gabriele Schaefer⁶ ; John D. Mayfield⁹ ; Juliann Chmielecki⁹ ; Philip J. Stephens⁹ ; Lee A. Albacker⁹ ; Yibing Yan⁵ ; Kyung Song⁶ ; Georgia Hatzivassiliou⁷ ; Charles Eigenbrot² ; Christine Yu² ; Andrey S. Shaw¹ ; Gerard Manning⁸ ; Nicholas J. Skelton³ ; Sarah G. Hymowitz² ; Shiva Malek¹ ; ^{shivam@gene.com" class="auth_mail" title="E-mail the corresponding author}

刊名：Cancer Cell

出版年：2016

7.57 - TPC-107, a next generation, HER2 selective covalent inhibitor demonstrates potent inhibition for activated mutations of HER2 while sparing EGFR inhibition

作者：K. Oguchi ; H. Irie ; K. Ito ; Y. Fujioka ; Y. Yamada ; T. Shimamura ; Y. Kawai ; Y. Shibata ; H. Araki ; T. Haruma ; A. Fujioka ; T. Sagara ; K. Matsuo ; T. Utsugi ; Y. Iwasawa

刊名：European Journal of Cancer

出版年：2016

8.Diagnostic significance of cerebrospinal fluid EGFR mutation analysis for leptomeningeal metastasis in non-small-cell lung cancer patients harboring an active EGFR mutation following gefitinib therapy failure

作者：Shinichi Sasaki ; M.D. ; Ph.D.^a ; ^{ssasaki@juntendo-urayasu.jp" class="auth_mail" title="E-mail the corresponding author} ; Yasuko Yoshioka ; M.D. ; Ph.D.^a ; Ryo Ko ; M.D. ; Ph.D.^b ; Yoko Katsura ; M.D. ; Ph.D.^b ; Yukiko Namba ; M.D. ; Ph.D.^b ; Takehito Shukuya ; M.D. ; Ph.D.^b ; Kenji Kido ; M.D. ; Ph.D.^c ; Shinichiro Iwakami ; M.D. ; Ph.D.^d ; Shigeru Tominaga ; M.D. ; Ph.D.^a ; Kazuhisa Takahashi ; M.D. ; Ph.D.^b

关键词：EGFR ; epidermal growth factor receptor ; TKI ; tyrosine kinase inhibitor ; NSCLC ; non-small cell lung cancer ; LM ; leptomeningeal metastasis ; CSF ; cerebrospinal fluid ; PCR ; polymerase chain reaction ; TTF ; time to treatment failure ; CNS ; central nervous system ; HER2 ; human epidermal growth factor receptor 2 ; WBRT ; whole brain radiotherapy

刊名：Respiratory Investigation

出版年：2016

9.Deletion Mutations Keep Kinase Inhibitors in the Loop

作者：Daniel M. Freed¹ ; ² ; Jin H. Park¹ ; ² ; Ravi Radhakrishnan³ ; Mark A. Lemmon¹ ; ² ; ^{mark.lemmon@yale.edu" class="auth_mail" title="E-mail the corresponding author}

刊名：Cancer Cell

出版年：2016

10.Gene Expression of the EGF System—a Prognostic Model in Non-Small Cell Lung Cancer Patients Without Activating EGFR Mutations

作者：Birgitte Sandfeld-Paulsen^* ; ^{birgne@rm.dk" class="auth_mail" title="E-mail the corresponding author} ; Birgitte Holst Folkersen^&dagger ; ; Torben Riis Rasmussen^&dagger ; ; Peter Meldgaard^&Dagger ; ; Boe S. Sorensen^*

刊名：Translational Oncology

出版年：2016

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