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在“Elsevier电子期刊”中，命中：342条，耗时：0.022989 秒

在所有数据库中总计命中：1,715条

1.A high throughput Cre-lox activated viral membrane fusion assay identifies pharmacological inhibitors of HIV entry

作者：Anthony M. Esposito^a ; Pamela Cheung^b ; Talia H. Swartz^a ; Hongru Li^a ; Tshidi Tsibane^c ; Natasha D. Durham^a ; Christopher F. Basler^c ; Dan P. Felsenfeld^b ; ¹ ; Benjamin K. Chen^a ; ^{benjamin.chen@mssm.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：HIV-1 ; Gag ; Cre recombinase ; Drug screening ; Virus entry ; Env ; Viral membrane fusion

刊名：Virology

出版年：2016

2.Design, synthesis and evaluation of small molecule CD4-mimics as entry inhibitors possessing broad spectrum anti-HIV-1 activity

作者：Francesca Curreli^a ; Dmitry S. Belov^b ; Ranjith R. Ramesh^a ; Naisargi Patel^a ; Andrea Altieri^b ; Alexander V. Kurkin^b ; Asim K. Debnath^a ;

关键词：NZFAIQJEZJFXEA-UHFFFAOYSA-N ; NZFAIQJEZJFXEA-UHFFFAOYSA-N ; JWCHVYUGZGKZBT-UHFFFAOYSA-N ; JWCHVYUGZGKZBT-UHFFFAOYSA-N ; SIDKVRRRTJZASD-UHFFFAOYSA-N ; SIDKVRRRTJZASD-UHFFFAOYSA-N ; XCGURELGTFUFHU-UHFFFAOYSA-N ; XCGURELGTFUFHU-UHFFFAOYSA-N ; BXHQTNRAUATSIP-UHFFFAOYSA-N ; BXHQTNRAUATSIP-UHFFFAOYSA-N ; CQYFELFFEPDKEA-UHFFFAOYSA-N ; BFKXFLVEJYIANA-UHFFFAOYSA-N ; ZMGIPXSXWYXEIK-UHFFFAOYSA-N ; LMBSXERDWURCBW-UHFFFAOYSA-N ; LMBSXERDWURCBW-UHFFFAOYSA-N ; RIRSQKBHJLLABG-UHFFFAOYSA-N ; RIRSQKBHJLLABG-UHFFFAOYSA-N ; HBUVBLU

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

3.Simplified molecular input line entry system-based descriptors in QSAR modeling for HIV-protease inhibitors

作者：Md Ataul Islam^a ; Tahir S. Pillay^a ; ^b ; ^{tspillay@gmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：HIV-protease ; Descriptors ; QSAR ; Monte Carlo method ; SMILES ; CORAL software

刊名：Chemometrics and Intelligent Laboratory Systems

出版年：2016

4.Tyrosine-sulfated V2 peptides inhibit HIV-1 infection via coreceptor mimicry

作者：Raffaello Cimbro^a ; ¹ ; Francis C. Peterson^b ; Qingbo Liu^a ; Christina Guzzo^a ; Peng Zhang^a ; Huiyi Miao^a ; Donald Van Ryk^a ; Xavier Ambroggio^c ; ² ; Darrell E. Hurt^c ; Luca De Gioia^d ; Brian F. Volkman^b ; Michael A. Dolan^c ; Paolo Lusso^a ; ^{plusso@niaid.nih.gov" class="auth_mail" title="E-mail the corresponding author}

关键词：HIV-1 ; Envelope ; Trimer ; Coreceptors ; Molecular mimicry ; Peptides ; Inhibitors ; Immune evasion

刊名：EBioMedicine

出版年：2016

5.A minimally cytotoxic CD4 mimic as an HIV entry inhibitor

作者：Takaaki Mizuguchi^a ; ^&dagger ; ; Shigeyoshi Harada^b ; ^&dagger ; ; Tomoyuki Miura^c ; Nami Ohashi^a ; Tetsuo Narumi^a ; Hiromi Mori^c ; Yu Irahara^a ; Yuko Yamada^a ; ^d ; Wataru Nomura^a ; Shuzo Matsushita^e ; Kazuhisa Yoshimura^b ; ^{ykazu@nih.go.jp" class="auth_mail" title="E-mail the corresponding author} ; Hirokazu Tamamura^a ; ^{tamamura.mr@tmd.ac.jp" class="auth_mail" title="E-mail the corresponding author}

关键词：CD4 mimic ; Conformational change in gp120 ; HIV entry inhibitor ; Pharmacokinetics

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

6.Core chemotype diversification in the HIV-1 entry inhibitor class using field-based bioisosteric replacement

作者：Marina Tuyishime^a ; Rae Lawrence^b ; Simon Cocklin^a ; ^{scocklin@drexelmed.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Computer-aided drug design ; HIV-1 envelope protein ; Field-based ; Bioisosteric replacement ; Scaffold-hopping ; SAR analysis ; Structure&ndash ; activity landscape ; Antiviral

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

7.Inhibitors of HIV-1 attachment: The discovery and structure-activity relationships of tetrahydroisoquinolines as replacements for the piperazine benzamide in the 3-glyoxylyl 6-azaindole pharmacophore

作者：Jacob J. Swidorski^a ; ; Zheng Liu^a ; Zhiwei Yin^a ; Tao Wang^a ; David J. Carini^a ; Sandhya Rahematpura^b ; Ming Zheng^b ; Kim Johnson^b ; Sharon Zhang^c ; Pin-Fang Lin^c ; Dawn D. Parker^b ; Wenying Li^b ; Nicholas A. Meanwell^a ; Lawrence G. Hamann^a ; ^&dagger ; ; Alicia Regueiro-Ren^a

关键词：HIV-1 ; Entry ; Attachment ; Tetrahydroisoquinoline ; Tetrahydropyrido[3 ; 4-d]pyrimidines ; BMS-663068

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

8.Design and synthesis of small molecule-sulfotyrosine mimetics that inhibit HIV-1 entry

作者：Cajetan Dogo-Isonagie^&dagger ; ; Su-Lin Lee^&dagger ; ; Katheryn Lohith^&dagger ; ; Hongbing Liu ; Sivakoteswara R. Mandadapu ; Sabrina Lusvarghi ; Robert D. O&rsquo ; Connor ; Carole A. Bewley ; ^{caroleb@mail.nih.gov" class="auth_mail" title="E-mail the corresponding author}

关键词：CD4 ; cluster of differentiation 4 ; CCR5 ; C&ndash ; C chemokine receptor type 5 ; CXCR4 ; C&ndash ; X&ndash ; C chemokine receptor type 4 ; CCR5 Nt ; CCR5 N-terminus ; CDR-H3 ; complementarity determining region heavy 3 ; HBF4 ; tetrafluoroboric acid ; DMSO ; dimethylsulfoxide

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

9.Discovery of non-peptide small molecular CXCR4 antagonists as anti-HIV agents: Recent advances and future opportunities

作者：Heng Zhang ; Dongwei Kang ; Boshi Huang ; Na Liu ; Fabao Zhao ; Peng Zhan ; ^{zhanpeng1982@sdu.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Xinyong Liu ; ^{xinyongl@sdu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：AIDS ; HIV-1 ; CXCR4 ; Small molecular ; Entry inhibitors ; Drug design

刊名：European Journal of Medicinal Chemistry

出版年：2016

10.Clinical, epidemiological and treatment failure data among HIV-1 non-B-infected patients in the Spanish AIDS Research Network Cohort

作者：Esther Torrecilla Garcí ; a^a ; Gonzalo Yebra Sanz^a ; Teresa Llá ; cer-Delicado^a ; Rafael Rubio Garcí ; a^b ; Juan Gonzá ; lez-Garcí ; a^c ; Federico Garcí ; a Garcí ; a^d ; José ; Ló ; pez-Aldeguer^e ; Ví ; ctor Asensi Á ; lvarez^f ; Á ; frica Holguí ; n Ferná ; ndez^a ; ^{africa.holguin@salud.madrid.org" class="auth_mail" title="E-mail the corresponding author} ; Cohort of the Spanish AIDS Research Network (CoRIS)

关键词：CoRIS ; HIV-1 ; Non-B variants ; Antiretroviral treatment (ART) ; Therapeutic failure (TF) to first ART ; Epidemiology

刊名：Enfermedades Infecciosas y Microbiología Clínica

出版年：2016

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