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在“Elsevier电子期刊”中，命中：161条，耗时：0.0459528 秒

在所有数据库中总计命中：991条

1.CD14⁺⁺ CD16⁻ monocytes are the main source of 11β-HSD type 1 after IL-4 stimulation

作者：Vidya Kunnathully^a ; ^{vid1488@gmail.com} ; Macarena Gomez-Lira^b ; ^{macarena.gomezlira@univr.it} ; Giulio Bassi^c ; ^{giulio.bassi@univr.it} ; Fabio Poli^a ; ^{fabio.poli@univr.it} ; Elisa Zoratti^d ; ^{elisa.zoratti@gmail.com} ; Valentina La Verde^a ; ^{valentina.laverde@gmail.com} ; Luca Idolazzi^a ; ^{luca.idolazzi@univr.it} ; Davide Gatti^a ; ^{davide.gatti@univr.it} ; Ombretta Viapiana^a ; ^{ombretta.viapiana@univr.it} ; Silvano Adami^a ; ^{silvano.adami@univr.it} ; Maurizio Rossini^a ; ^{maurizio.rossini@univr.it}

关键词：CD14 ; CD14++ CD16&minus ; ; CD16 ; CD14+ CD16+ ; ; HTRF ; Homogeneous Time-Resolved Fluorescence ; 11β-HSDs ; 11β-hydroxysteroid dehydrogenases ; CFSE ; carboxyfluorescein-diacetate-succimidyl-ester method ; rMFI ; median fluorescence intensity

刊名：International Immunopharmacology

出版年：2017

2.Structural Characterisation Reveals Mechanism of IL-13-Neutralising Monoclonal Antibody Tralokinumab as Inhibition of Binding to IL-13Rα1 and IL-13Rα2

作者：B. Popovic¹ ; ^{popovicb@medimmune.com} ; J. Breed² ; D.G. Rees¹ ; M.J. Gardener¹ ; L.M.K. Vinall¹ ; B. Kemp¹ ; J. Spooner¹ ; J. Keen¹ ; R. Minter¹ ; F. Uddin³ ; G. Colice⁴ ; T. Wilkinson¹ ; T. Vaughan¹ ; R.D. May⁵

关键词：IL ; interleukin ; Th2 ; T helper type 2 ; PDB ; Protein Data Bank ; VH ; variable heavy ; VL ; variable light region ; CDR ; complementary-determining region ; FW ; framework ; PBS ; phosphate-buffered saline ; HPLC-SEC ; high-performance liquid chromatography&ndash ; size-exclusion chromatography ; HTRF ; homogeneous time resolved fluorescence

刊名：Journal of Molecular Biology

出版年：2017

3.Design, synthesis and pharmacological evaluation of 4-hydroxyphenylglycine and 4-hydroxyphenylglycinol derivatives as GPR88 agonists

作者：Chunyang Jin ; ^cjin@rti.org ; Ann M. Decker ; Tiffany L. Langston

关键词：2-PCCA ; (1R ; 2R)-2-(pyridin-2-yl)cyclopropane carboxylic acid ((2S ; 3S)-2-amino-3-methylpentyl)-(4&prime ; -propylbiphenyl-4-yl)amide ; 2-AMPP ; (2S)-N-((1R)-2-amino-1-(4-(2-methyl-pentyloxy)phenyl)ethyl)-2-phenylpropanamide ; SAR ; structure activity relationship ; PPLS ; pre-prolactin leader sequence ; HA ; human influenza hemagglutinin ; HTRF ; homogeneous time resolved fluorescence ; MS ; mass spectroscopy ; TLC ; thin layer chromatography ; DIPEA ; N ; N-diisopropylethylamine ; DCM ; dichloromethane ; DEAD ; diethyl

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

4.Homogeneous time-resolved G protein-coupled receptor-ligand binding assay based on fluorescence cross-correlation spectroscopy

作者：Thomas Antoine^a ; ¹ ; David Ott^a ; ¹ ; Katharina Ebell^a ; Kerrin Hansen^a ; Luc Henry^b ; Frank Becker^a ; Stefan Hannus^a ; ^{stefan.hannus@intana.de" class="auth_mail" title="E-mail the corresponding author}

关键词：GPCR ; Homogeneous time-resolved binding assay ; Fluorescence correlation spectroscopy ; Fluorescence cross-correlation spectroscopy ; Affinity determination ; Binding kinetics

刊名：Analytical Biochemistry

出版年：2016

5.A high-throughput screening-compatible homogeneous time-resolved fluorescence assay measuring the glycohydrolase activity of human poly(ADP-ribose) glycohydrolase

作者：Alexandra I.J. Stowell^a ; ^{alex.stowell@cruk.manchester.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; Dominic I. James^a ; Ian D. Waddell^a ; Neil Bennett^b ; Caroline Truman^b ; Ian M. Hardern^b ; Donald J. Ogilvie^a

关键词：Poly(ADP-ribose) glycohydrolase ; Poly(ADP-ribose) polymerase ; Homogeneous time-resolved fluorescence ; Small molecule inhibitors ; High-throughput screening

刊名：Analytical Biochemistry

出版年：2016

6.Building homogeneous time-resolved fluorescence resonance energy transfer assays for characterization of bivalent inhibitors of an inhibitor of apoptosis protein target

作者：Charu Chaudhry^a ; ^{charu.chaudhry@bms.com" class="auth_mail" title="E-mail the corresponding author} ; Jonathan Davis^b ; Yong Zhang^c ; Shana Posy^b ; Ming Lei^a ; Henry Shen^d ; Chunhong Yan^e ; Brigitte Devaux^f ; Litao Zhang^a ; Yuval Blat^a ; William Metzler^a ; Robert M. Borzilleri^c ; Randy L. Talbott^d

关键词：XIAP ; Smac ; Apoptosis ; HTRF ; Assay ; Off-rate

刊名：Analytical Biochemistry

出版年：2016

7.A novel cell-based duplex high-throughput screening assay combining fluorescent Ca²⁺ measurement with homogeneous time-resolved fluorescence technology

作者：Lá ; szló ; Kiss ; Attila Cselenyák ; Á ; gnes Varga ; Andrá ; s Visegrá ; dy ; ^{visegrady@richter.hu" class="auth_mail" title="E-mail the corresponding author}

关键词：Cell-based assays ; High-throughput screening ; Multiplex assays and technology ; Fluorescent Ca2+ measurement ; HTRF technology

刊名：Analytical Biochemistry

出版年：2016

8.Interaction of 1-pyrene sulfonic acid sodium salt with human serum albumin

作者：Malgorzata Steblecka ^{gosia@mitr.p.lodz.pl" class="auth_mail" title="E-mail the corresponding author} ; Marian Wolszczak ^{marianwo@mitr.p.lodz.pl" class="auth_mail" title="E-mail the corresponding author} ; Ewa Szajdzinska-Pietek ; ^{espietek@mitr.p.lodz.pl" class="auth_mail" title="E-mail the corresponding author}

关键词：PSA ; 1-pyrene sulfonic acid ; HSA ; Human serum albumin ; PBS ; Phosphate buffer saline ; TCSPC ; Time correlated single photon counting ; PBAC ; 4-(1-pyrenyl) butylamine hydrochloride ; BSA ; Bovine serum albumin ; RET ; Resonance energy transfer

刊名：Journal of Luminescence

出版年：2016

9.Tyrosine kinase inhibitory activity of dehydroabietylamine derivatives tested by homogeneous time-resolved fluorescence based high throughput screening model

作者：Tao-Tao ZHOU ; Ling HE ; Ming YAN ; Lu-Yong ZHANG ; Jian-Guo HE ; Xiao-Ping RAO

关键词：Protein tyrosine kinases ; Homogeneous time-resolved fluorescence ; High throughput screening ; Dehydroabietylamine derivatives

刊名：Chinese Journal of Natural Medicines

出版年：September, 2013

10.Photophysical properties and excited state intramolecular proton transfer in 2-hydroxy-5-[(E)-(4-methoxyphenyl)diazenyl]benzoic acid in homogeneous solvents and micro-heterogeneous environments

作者：Pynsakhiat Miki Gashnga ; T. Sanjoy Singh ; Tushar S. Basu Baul ; Sivaprasad Mitra

关键词：Excited state intramolecular proton transfer ; Spontaneous emission ; Critical micelle concentration ; Binding constant ; Fluorescence decay

刊名：Journal of Luminescence

出版年：April, 2014

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