搜索页_ IκB

设为首页

收藏本站

网站地图 | English | 公务邮箱

About the library

Background
History
Leadership
Organization

Readers' Guide

Opening Hours
Collections
Help Via Email

Publications

Electronic Information Resources

常用资源

在“Elsevier电子期刊”中，命中：248条，耗时：小于0.01 秒

1.IκB kinase inhibition as a potential treatment of osteoarthritis - results of a clinical proof-of-concept study

作者：K. Grothe^&dagger ; ; ^{Kirsten.Grothe@sanofi.com} ; K. Flechsenhar^&dagger ; ; ^{Klaus.Flechsenhar@sanofi.com} ; T. Paehler^&Dagger ; ; ^{Tobias.Paehler@sanofi.com} ; O. Ritzeler^§ ; ; ^{Olaf.Ritzeler@sanofi.com} ; J. Beninga^‖ ; ^{Jochen.Beninga@sanofi.com} ; J. Saas^&dagger ; ; ^{Joachim.Saas@sanofi.com} ; M. Herrmann^&dagger ; ; ^{Matthias.Herrmann@sanofi.com} ; K. Rudolphi^&dagger ; ; ^{Karl.Rudolphi@sanofi.com}

关键词：IκB kinase inhibitor ; Slow-release formulation ; Intra-articular injection ; Treatment of knee osteoarthritis ; Clinical findings

刊名：Osteoarthritis and Cartilage

出版年：2017

2.Deubiquitinase USP12 promotes LPS induced macrophage responses through inhibition of IκBα

作者：Tapan Kumar Singh Nayak ; Neeraja P. Alamuru-Yellapragada ; Kishore V.L. Parsa ; ^{kishorep@drils.org}

关键词：USP12 ; LPS ; Macrophages ; Inflammation

刊名：Biochemical and Biophysical Research Communications

出版年：2017

3.Artesunate suppresses RANKL-induced osteoclastogenesis through inhibition of PLCγ1-Ca²⁺-NFATc1 signaling pathway and prevents ovariectomy-induced bone loss

作者：Xiangzhou Zeng^a ; ^b ; Yueyang Zhang^a ; Song Wang^c ; Keng Wang^a ; Lei Tao^a ; Min Zou^a ; Nana Chen^a ; Jiake Xu^d ; Shuwen Liu^a ; ^{liusw@smu.edu.cn} ; Xiaojuan Li^a ; ^{lixiaoj@smu.edu.cn}

关键词：Art ; artesunate ; RANKL ; receptor activator of nuclear factor-κB (NF-κB) ligand ; M-CSF ; macrophage colony-stimulating factor ; TRAP ; tartrate-resistant acid phosphatase ; TRAF6 ; tumor necrosis factor receptor associated factor 6 ; IκB ; inhibitor of nuclear factor-κB ; NF-κB ; nuclear factor-κB ; NFATc1 ; nuclear factor of activated T cells c1 ; Micro-CT ; microcomputer tomography

刊名：Biochemical Pharmacology

出版年：2017

4.Identification of novel peptides against TNF-α using phage display technique and in silico modeling of their modes of binding

作者：Ali Akbar Alizadeh^a ; ^b ; Maryam Hamzeh-Mivehroud^a ; ^b ; ^{hamzehm@tbzmed.ac.ir} ; ^{maryam_h_7860@yahoo.com} ; Malak Farajzadeh^a ; Siavoush Dastmalchi^a ; ^b ; ^{dastmalchi.s@tbzmed.ac.ir} ; ^{siavoush11@yahoo.com}

关键词：ELISA ; enzyme-linked immunosorbent assay ; GST ; glutathione S-transferase ; IκB-α ; inhibitor of kappa B ; PLP ; piecewise linear potential

刊名：European Journal of Pharmaceutical Sciences

出版年：2017

5.RhoA GTPase oxidation stimulates cell proliferation via nuclear factor-κB activation

作者：Jae-Gyu Kim^a ; Hyung-Joo Kwon^b ; ^c ; Guang Wu^c ; Yohan Park^a ; Jae-Yong Lee^a ; ^d ; Jaebong Kim^a ; ^d ; Sung-Chan Kim^a ; ^d ; Myoen Choe^e ; Seung Goo Kang^f ; Goo-Young Seo^g ; Pyeung-Hyeun Kim^g ; Jae-Bong Park^a ; ^c ; ^d ; ^{jbpark@hallym.ac.kr}

关键词：CA ; constitutively active ; DMEM ; Dulbecco's modified Eagle's medium ; DN ; dominant negative ; GAP ; GTPase activating protein ; GAPDH ; glyceraldehyde-3-phosphate dehydrogenase ; GDF ; GDI displacement factor ; GDI ; guanine nucleotide dissociation inhibitor ; GEF ; guanine nucleotide exchange factor ; GSH ; glutathione ; Rhotekin-RBD ; Rhotekin Rho-binding domain ; ROCK ; Rho-dependent coiled-coil kinase ; ROS ; reactive oxygen species ; WT ; wild-type ; NF-κB ; nuclear factor-κB ; IκB ; inhibitor of NF-κB ; IKK ; IκB ki

刊名：Free Radical Biology and Medicine

出版年：2017

6.Maspin inhibits macrophage phagocytosis and enhances inflammatory cytokine production via activation of NF-κB signaling

作者：Yimeng Wang^a ; ^b ; Luguo Sun^b ; Zhenbo Song^a ; ^c ; Danfeng Wang^a ; ^b ; Yongli Bao^a ; ^{baoyl800@nenu.edu.cn} ; Yuxin Li^b ; ^c ; ^{liyx486@nenu.edu.cn}

关键词：Arg-1 ; arginase 1 ; CM ; conditioned medium ; FITC ; fluorescein isothiocyanate ; GAPDH ; glyceraldehyde-3-phosphate dehydrogenase ; iNOS ; inducible nitric oxide synthase ; IFN ; interferon ; IKK ; inhibitor of NF-κB kinase ; IκB ; inhibitor of NF-κB ; LPS ; lipopolysaccharide ; Mφ ; macrophage ; NBS ; neonatal bovine serum ; PDTC ; pyrrolidine dithiocarbamate ; rMaspin ; recombinant Maspin ; SEM ; standard error of the mean

刊名：Molecular Immunology

出版年：2017

7.Sargachromenol protects against vascular inflammation by preventing TNF-α-induced monocyte adhesion to primary endothelial cells via inhibition of NF-κB activation

作者：Wi-Gyeong Gwon^a ; Eun-Ji Joung^a ; Mi-Sung Kwon^a ; Su-Jin Lim^a ; Tadanobu Utsuki^b ; Hyeung-Rak Kim^a ; ^{hrkim@pknu.ac.kr}

关键词：BCECF-AM ; 2&prime ; 7&prime ; -Bis(2-carboxyethyl)-5(6)-carboxyfluorescein acetoxy-methylester ; BSA ; bovine serum albumin ; DAPI ; 4&prime ; 6-diamidino-2-phenylindole ; DCFH-DA ; 2&prime ; 7&prime ; -dichlorofluorescin diacetate ; 4&rsquo ; 6-diamidino-2-phenylindole ; DMSO ; dimethyl sulfoxide ; ECL ; enhanced chemiluminescence ; EGM-2 ; endothelial cell growth medium ; HUVEC ; human umbilical vein endothelial cell ; GAPDH ; glyceraldehyde-3-phosphate dehydrogenase ; ICAM-1 ; intracellular adhesion molecule-1 ; IκB-α

刊名：International Immunopharmacology

出版年：2017

8.Intracellular signaling modifications involved in the anti-inflammatory effect of 4-alkoxy-6,9-dichloro[1,2,4]triazolo[4,3-a]quinoxalines on macrophages

作者：Antonio J. Ruiz-Alcaraz^a ; ^ajruiz@um.es ; Marí ; a Tristá ; n-Manzano^a ; Antonio Guirado^b ; Jesú ; s Gá ; lvez^c ; Marí ; a Martí ; nez-Esparza^a ; Pilar Garcí ; a-Peñ ; arrubia^a ; ^{pigarcia@um.es}

关键词：ATF ; activating transcription factor ; CCM ; complete culture medium ; ERK ; extracellular signal-regulated kinase ; IKK ; IκB kinase ; IL-6 ; interleukin 6 ; JNK ; c-Jun N-terminal kinase ; LPS ; lipopolysaccharide ; MAPK ; mitogen-activated protein kinase ; NSAIDs ; non-steroidal anti-inflammatory drugs ; NFκB ; nuclear factor kappa-light-chain-enhancer of activated B cells ; PAMP ; pathogen-associated molecular patterns ; PI3K ; phosphatidylinositol 3-kinase ; PKB ; protein kinase B ; PRRs ; PAMP recognition receptors

刊名：European Journal of Pharmaceutical Sciences

出版年：2017

9.Gamma irradiation enhanced Tollip-mediated anti-inflammatory action through structural modification of quercetin in lipopolysaccharide-stimulated macrophages

作者：Eui-Baek Byun^a ; ^b ; Beom-Su Jang^a ; ^b ; Hye-Min Kim^a ; ^d ; Mi-So Yang^c ; Nak-Yun Sung^d ; Eui-Hong Byun^d ; ^{ehbyun80@kongju.ac.kr}

关键词：HPLC ; high-performance liquid chromatography ; HRP ; horseradish peroxidase ; LPS ; lipopolysaccharide ; Tollip ; toll-interacting protein ; TLR ; toll-like receptor ; MHC ; major histocompatibility complex ; NF-κB ; nuclear factor-κB ; IκB ; inhibitor of κB ; TNF-α ; tumor necrosis factor-α ; IL ; interleukin ; MAPK ; mitogen-activated protein kinase ; COX ; cyclooxygenase ; iNOS ; nitric oxide synthase ; NO ; nitric oxide ; ELISA ; enzyme-linked immunosorbent assay ; PGE2 ; prostaglandin E2 ; ROS ; reactive oxygen species ; S

刊名：International Immunopharmacology

出版年：2017

10.Pathological α-synuclein exacerbates the progression of Parkinson’s disease through microglial activation

作者：Qiu-Shuang Zhang^a ; Yang Heng^a ; Yu-He Yuan^a ; ^{yuanyuhe@imm.ac.cn} ; Nai-Hong Chen^a ; ^b ; ^{chennh@imm.ac.cn}

关键词：AKT ; protein kinase B ; AP-1 ; activator protein-1 ; BV-2 ; immortalized murine microglia cell line ; CD11b ; cluster of differentiation 11b ; CD36 ; cluster of differentiation 36 ; CD44 ; cluster of differentiation 44 ; CD68 ; cluster of differentiation 68 ; CNS ; central nervous system ; COX-2 ; cyclooxygenase-2 ; cPLA2 ; cytosolic phospholipase A2 ; EP2 ; prostaglandin E2 receptor subtype 2 ; ERK ; extracellular regulated kinases ; FcγRs ; Fc gamma receptors ; IKK ; IκB kinase ; IL-1β ; interleukin-1-β ; IL-6 ; interleuki

刊名：Toxicology Letters

出版年：2017

按检索点细分(248)

题名(25)

关键词(100)

文摘(166)

按出版年细分(248)

2017年(31)

2016年(175)

2015年(34)

2014年(3)

2012年(2)

2011年(3)