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内部出版物
在“
Elsevier电子期刊
”中,
命中:
695
条,耗时:小于0.01 秒
1.
Pathological concentration of zinc dramatically accelerates abnormal aggregation of full-length human Tau and thereby significantly increases Tau toxicity in neuronal cells
作者:
Ji-Ying Hu
a
;
De-Lin Zhang
a
;
Xiao-Ling Liu
a
;
Xue-Shou Li
a
;
Xiao-Qing Cheng
b
;
Jie Chen
a
;
Hai-Ning Du
b
;
Yi Liang
a
;
liangyi@whu.edu.cn
关键词:
AD
;
Alzheimer disease
;
TEM
;
transmission electron microscopy
;
ThS
;
thioflavin S
;
PI
;
propidium iodide
;
DAPI
;
4&prime
;
6&prime
;
-diamino-2-phenylindole dihydrochloride
;
IAPP
;
islet amyloid polypeptide
;
TDP-43
;
TAR DNA-binding protein of 43
;
kDa
;
MTT
;
3-(4
;
5-dimethylthiazol-2-yl)-2
;
5-diphenyltetrazolium bromide
;
ITC
;
isothermal titration calorimetry
;
GSK-3β
;
glycogen synthase kinase-3β
刊名:Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
出版年:2017
2.
Mesoscopic Properties and Molecular Mechanisms of
IAPP
Amyloid Inhibition and Remodeling with Small Molecules
作者:
Aleksandr Kakinen
1
;
Bo Wang
2
;
Xinwei Ge
2
;
Raffaele Mezzenga
3
;
Thomas P. Davis
1
;
4
;
Feng Ding
2
;
Pu Chun Ke
1
刊名:Biophysical Journal
出版年:2017
3.
Phase 2 Study of Erlotinib in Combination With Linsitinib (OSI-906) or Placebo in Chemotherapy-Naive Patients With Non-Small-Cell Lung Cancer and Activating Epidermal Growth Factor Receptor Mutations
作者:
Natasha B. Leighl
1
;
Naiyer A. Rizvi
2
;
Lopes Gilberto de Lima Jr.
3
;
4
;
Wichit Arpornwirat
5
;
Charles M. Rudin
6
;
Alberto A. Ch
iapp
ori
7
;
Myung-Ju Ahn
8
;
Laura Q.M. Chow
9
;
Lyudmila Bazhenova
10
;
Arunee Dechaphunkul
11
;
Patrapim Sunpaweravong
12
;
Keith Eaton
13
;
14
;
Jihong Chen
15
;
Sonja Medley
15
;
Srinivasu Poondru
15
;
Margaret Singh
15
;
Joyce Steinberg
15
;
Rosalyn A. Juergens
16
;
juergensr@hhsc.ca
;
Shirish M. Gadgeel
17
;
18
关键词:
Combination
;
Epidermal growth factor receptor inhibitor
;
First-line therapy
;
Insulin-like growth factor-1 inhibitor
;
Tyrosine kinase inhibitor
刊名:Clinical Lung Cancer
出版年:2017
4.
Non-invasive, non-ionizing fatty liver assessment by means of a new ultrasound-based imaging system: The Steatometer
作者:
N. Di Lascio
1
;
nicole.dilascio@ifc.cnr.it
;
D. D'Elia
2
;
C. Avigo
1
;
A. Salvati
3
;
N. Martini
4
;
D. Ch
iapp
ino
4
;
L. Ghiadoni
5
;
F. Bonino
5
;
M.R. Brunetto
3
;
F. Faita
1
刊名:Nutrition, Metabolism and Cardiovascular Diseases
出版年:2017
5.
403 Comparison of Sexual Function in Transsexual Women Who Underwent Sex Reassignment Surgery by Two Different Techniques
作者:
F. Vedovo
1
;
N. Pavan
1
;
G. Ch
iapp
arrone
1
;
G. Liguori
1
;
F. Barbone
2
;
C. Trombetta
1
刊名:The Journal of Sexual Medicine
出版年:2017
6.
Lipoprotein-associated phospholipase A2 circulating levels in the general population of the Montignoso Study
作者:
A. Sereni
1
;
serenialice@gmail.com
;
A.M. Gori
1
;
A. Kura
1
;
R. Marcucci
1
;
B. Giusti
1
;
F. Sofi
1
;
D. Ch
iapp
ino
2
;
D. Della Latta
2
;
R. Abbate
1
;
G.F. Gensini
1
刊名:Nutrition, Metabolism and Cardiovascular Diseases
出版年:2017
7.
Peptides Composed of Alternating L- and D-Amino Acids Inhibit Amyloidogenesis in Three Distinct Amyloid Systems Independent of Sequence
作者:
Jackson Kellock
1
;
Gene Hopping
1
;
Byron Caughey
2
;
Valerie Daggett
1
;
daggett@uw.edu" class="auth_mail" title="E-mail the corresponding author
关键词:
Aβ42
;
amyloid Beta (1&ndash
;
42)
;
IAPP
;
islet amyloid polypeptide
;
NOESY
;
nuclear Overhauser effect spectroscopy
;
TTR
;
transthyretin
;
ThT
;
Thioflavin T
;
CR
;
Congo red
;
CD
;
circular dichroism spectroscopy
;
FTIR
;
Fourier Transform Infrared
;
HFIP
;
hexafluoro &ndash
;
1
;
1
;
1
;
3
;
3
;
3 &ndash
;
isopropanol
;
RT
;
room temperature
刊名:Journal of Molecular Biology
出版年:2016
8.
How the imidazole ring modulates amyloid formation of islet amyloid polypeptide: A chemical modification study
作者:
Xin Zhang
a
;
1
;
Junjun Liu
a
;
1
;
lianqi Huang
a
;
Xin Yang
a
;
Robert B. Petersen
b
;
c
;
d
;
Yue Sun
e
;
Hao Gong
a
;
Ling Zheng
e
;
lzheng217@hotmail.com" class="auth_mail" title="E-mail the corresponding author
;
Kun Huang
a
;
kunhuang2008@hotmail.com" class="auth_mail" title="E-mail the corresponding author
关键词:
IAPP
;
islet amyloid polypeptide
;
h
IAPP
;
human
IAPP
;
DEPC
;
diethylpyrocarbonate
;
DMI
;
DEPC-modified h
IAPP
;
HFIP
;
1
1133 ;
3-hexafluoro-2-propanol
;
ThT
;
thioflavin-T
刊名:Biochimica et Biophysica Acta (BBA) - General Subjects
出版年:2016
9.
Scaffolded multimers of h
IAPP
20-29
peptide fragments fibrillate faster and lead to different fibrils compared to the free hIAPP
20-29
peptide fragment
作者:
Heidi F. Christoffersen
a
;
b
;
Maria Andreasen
a
;
b
;
1
;
Shuai Zhang
a
;
Erik Holm Nielsen
a
;
b
;
Gunna Christiansen
c
;
Mingdong Dong
a
;
Troels Skrydstrup
a
;
b
;
ts@inano.au.dk" class="auth_mail" title="E-mail the corresponding author
;
Daniel E. Otzen
a
;
b
;
dao@inano.au.dk" class="auth_mail" title="E-mail the corresponding author
关键词:
AFM
;
Atomic force microscopy
;
CD
;
circular dichroism
;
CC
;
Critical concentration of fibrillation
;
CuAAC
;
Cu(I)-catalyzed alkyne&ndash
;
azide cycloaddition
;
αCD
;
α-cyclodextrin
;
N3P3
;
cyclotriphosphazene
;
DIC
;
Diisopropylcarbodiimide
;
DIPEA
;
N
;
N-diisopropylethylamine
;
FTIR
;
Fourier transform infra-red
;
h
IAPP
20&ndash
;
29
;
N3P3
;
hexakis(4-((4-(N-(2-(2-(O-(SNNFGAIL)SS-aminomethoxy)ethoxy)ethyl)pent-2-ylamide)-1H-1
2 ;
3-triazol-1-yl)methyl)phenoxy)cyclotriphosphazene
;
h
IAPP
;
human islet amyloid polypepti
刊名:Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
出版年:2015
10.
Secondary structure propensity and chirality of the amyloidophilic peptide p5 and its analogues impacts ligand binding - In vitro characterization
作者:
Jonathan S. Wall
a
;
b
;
jwall@utmck.edu" class="auth_mail" title="E-mail the corresponding author
;
Angela Williams
a
;
Craig Wooliver
a
;
Emily B. Martin
a
;
Xiaolin Cheng
c
;
R. Eric Heidel
d
;
Stephen J. Kennel
a
;
b
关键词:
TFE
;
trifluoroethanol
;
CD
;
circular dichroism
;
SPR
;
surface plasmon resonance
;
AL
;
light chain associated amyloid
;
ATTR
;
transthyretin-associated amyloid
;
AA
;
inflammation-associated amyloidosis
;
IAPP
;
islet amyloid-associated polypeptide
刊名:Biochemistry and Biophysics Reports
出版年:2016
1
2
3
4
5
6
7
8
9
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