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在“Elsevier电子期刊”中，命中：190条，耗时：小于0.01 秒

1.IMPDH2 Is an Intracellular Target of the Cyclophilin A and Sanglifehrin A Complex

作者：Khian Hong Pua¹ ; ² ; Dylan T. Stiles¹ ; ² ; Mathew E. Sowa² ; ³ ; Gregory L. Verdine¹ ; ² ; ⁴ ; ⁵ ; ^{gregory_verdine@harvard.edu}

关键词：cyclophilin A ; sanglifehrin A ; inosine-5&prime ; -monophosphate dehydrogenase ; cystathionine-β-synthase domains ; protein-protein interactions

刊名：Cell Reports

出版年：2017

2.Determination of inosine 5′-monophosphate dehydrogenase activity in red blood cells of thiopurine-treated patients using HPLC

作者：Audrey Beringer^a ; ^b ; Antony Citterio-Quentin^a ; ^b ; Rebeca Obenza Otero^a ; Clé ; mence Gustin^a ; ^b ; Rebecca Clarke^a ; ^c ; Jean-Paul Salvi^a ; Roselyne Boulieu^a ; ^b ; ^{roselyne.boulieu@univ-lyon1.fr}

关键词：6-MeMPN ; 6-methyl mercaptopurine nucleotides ; 6-MP ; 6-mercaptopurine ; 6-TGN ; 6-thioguanine nucleotides ; AZA ; azathioprine ; β-NAD ; β-nicotinamide adenine dinucleotide ; DTT ; dithiothreitol ; IBD ; inflammatory bowel disease ; IMP ; inosine 5&prime ; -monophosphate ; IMPDH ; inosine 5&prime ; -monophosphate dehydrogenase ; ITPA ; inosine triphosphate pyrophosphatase ; meTIMP ; methyl thioinisone 5&prime ; -monophosphate ; MPA ; mycophenolic acid ; RBCs ; red blood cells ; TPMT ; thiopurine S-methyltransferase ; XMP ; xant

刊名：Journal of Chromatography B

出版年：2017

3.Autophagy suppression sensitizes glioma cells to IMP dehydrogenase inhibition-induced apoptotic death

作者：Andjelka M. Isakovic^a ; Marija Dulovic^a ; Ivanka Markovic^a ; Tamara Kravic-Stevovic^b ; Vladimir Bumbasirevic^b ; Vladimir Trajkovic^c ; ^{vtrajkovic@med.bg.ac.rs} ; Aleksandra Isakovic^a ; ^{aisakovic@med.bg.ac.rs}

关键词：Ribavirin ; IMP dehydrogenase ; Autophagy ; Apoptosis ; mTOR ; Akt

刊名：Experimental Cell Research

出版年：2017

4.Synthesis of α-santonin derivatives for diminutive effect on T and B-cell proliferation and their structure activity relationships

作者：Praveen K. Chinthakindi^a ; ^b ; Jasvinder Singh^c ; ^d ; Shilpa Gupta^c ; Amit Nargotra^e ; Priya Mahajan^e ; Anupurna Kaul^c ; Zabeer Ahmed^c ; Surrinder Koul^a ; ^{skoul@iiim.ac.in} ; Payare L. Sangwan^a ; ^{plsangwan@iiim.ac.in}

关键词：α-Santonin ; Immunosuppressant ; ConA ; LPS ; T and B cell ; SARs ; In silico study

刊名：European Journal of Medicinal Chemistry

出版年：2017

5.Neural crest requires Impdh2 for development of the enteric nervous system, great vessels, and craniofacial skeleton

作者：Jonathan I. Lake^a ; Marina Avetisyan^a ; Albert G. Zimmermann^b ; Robert O. Heuckeroth^c ; ^{Heuckerothr@email.chop.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Neural crest ; De novo purine synthesis ; Enteric nervous system

刊名：Developmental Biology

出版年：2016

6.Ideal oral combinations to eradicate HCV: The role of ribavirin

作者：Christophe Hé ; zode¹ ; ^{christophe.hezode@hmn.aphp.fr" class="auth_mail" title="E-mail the corresponding author} ; Jean-Pierre Bronowicki²

关键词：HCV ; hepatitis C virus ; SVR ; sustained virological response ; RBV ; ribavirin ; IFN ; interferon ; Peg-IFN ; pegylated interferon ; DAA ; direct-acting antiviral ; ALT ; alanine transaminase ; GTP ; guanosine triphosphate ; IMPDH ; inosine monophosphate dehydrogenase ; APRI ; aspartate aminotransferase ; platelet ratio index ; SOF ; sofosbuvir ; SMV ; simeprevir ; DCV ; daclatasvir ; LDV ; ledipasvir ; ASV ; asunaprevir ; RAVs ; resistance-associated variants ; BMS ; Bristol-Myers Squibb

刊名：Journal of Hepatology

出版年：2016

7.High expression of CD38, CD69, CD95 and CD154 biomarkers in cultured peripheral T lymphocytes correlates with an increased risk of acute rejection in liver allograft recipients

作者：Francisco Boix^a ; Olga Millan^b ; ^c ; David San Segundo^d ; Esther Mancebo^e ; Antoni Rimola^c ; ^f ; Emilio Fabrega^g ; Virginia Fortuna^b ; Anna Mrowiec^a ; Maria J. Castro-Panete^e ; Jesus de la Peñ ; a^h ; Santiago Llorenteⁱ ; Alfredo Minguela^a ; ^c ; Jose M. Bolarin^a ; Estela Paz-Artal^e ; Marcos Lopez-Hoyos^d ; Mercé ; Brunet^b ; ^c ; ¹ ; Manuel Muro^a ; ^c ; ¹ ; ^{manuel.muro@carm.es" class="auth_mail" title="E-mail the corresponding author}

关键词：AR ; acute rejection ; AUC ; area under the curve ; CNI ; calcineurin inhibitors ; Con-A ; concanavalin A ; CsA ; cyclosporine A ; FCS ; fetal calf serum ; FL1 ; forward light 1 ; HC ; healthy controls ; IMPDH ; inosine monophosphate dehydrogenase ; LGR ; liver graft recipients ; MFI ; medium fluorescence intensity ; MMF ; mycophenolate mophetil ; NAR ; non-acute rejection ; OLT ; orthotopic liver transplantation ; PBS ; phosphate buffered saline ; PBMC ; peripheral blood mononuclear cells ; PK ; pharmacokinetics ; PD ; pharmacod

刊名：Immunobiology

出版年：2016

8.Hepatitis E virus mutations associated with ribavirin treatment failure result in altered viral fitness and ribavirin sensitivity

作者：Yannick Debing¹ ; ^&dagger ; ; Christophe Ramiè ; re² ; ³ ; ⁴ ; ⁵ ; ^&dagger ; ; Kai Dallmeier¹ ; Gé ; raldine Piorkowski⁶ ; Mary-Anne Trabaud² ; Fanny Lebossé ; ⁴ ; ⁵ ; ⁷ ; ⁸ ; Caroline Scholtè ; s² ; ³ ; ⁴ ; ⁵ ; Magali Roche⁹ ; Catherine Legras-Lachuer⁹ ; ¹⁰ ; Xavier de Lamballerie⁶ ; ¹¹ ; Patrice André ; ² ; ³ ; ⁴ ; ⁵ ; ^&Dagger ; ; Johan Neyts¹ ; ^&Dagger ; ; ^{johan.neyts@rega.kuleuven.be" class="auth_mail" title="E-mail the corresponding author}

关键词：HEV ; hepatitis E virus ; RBV ; ribavirin ; ALT ; alanine aminotransferase ; IU ; international units ; γGT ; γ-glutamyltransferase ; CLL ; chronic lymphoid leukemia ; NGS ; next-generation sequencing ; RdRp ; RNA-dependent RNA polymerase ; HVR ; hypervariable region ; ORF ; open reading frame ; IMPDH ; inosine 5&prime ; -monophosphate dehydrogenase ; MPA ; mycophenolic acid ; LOD ; limit of detection ; RLU ; relative light units ; FBS ; fetal bovine serum ; HS ; human serum ; WT ; wild-type ; VC ; virus control

刊名：Journal of Hepatology

出版年：2016

9.Liquid chromatography-mass spectrometry for measuring deoxythioguanosine in DNA from thiopurine-treated patients

作者：Sally A. Coulthard^a ; ^{sally.coulthard@newcastle.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; Phil Berry^b ; Sarah McGarrity^b ; Azhar Ansari^c ; Christopher P.F. Redfern^b

关键词：ALL ; Acute childhood leukemia ; 6-MP or MP ; 6-mercaptopurine ; AZA ; azathioprine ; IBD ; inflammatory bowel disease ; MeMP ; methylmercaptopurine ; MeMP-d3 ; Methymercaptopurine-D3 ; TIMP ; thioinosine monophosphate ; TIDP ; thioinosine diphosphate ; TITP ; thioinosine triphosphate ; TXMP ; thioxanthine monophosphate ; TGMP ; thioguanosine monophosphate ; TGDP ; thioguanosine diphosphate ; TGTP ; thioguanosine triphosphate ; IMPDH ; inosine-monophosphate dehydrogenase ; TPMT ; thiopurine methyl-transferase ; HGPRT ; hypoxa

刊名：Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences

出版年：2016

10.MP85-04 DE NOVO GTP SYNTHESIS IS CRITICAL FOR CELL MIGRATION THROUGH IMPDH2 IN RENAL CELL CARCINOMA

作者：Hirofumi Yoshino ; Hideki Hideki ; Masayuki Nakagawa

刊名：The Journal of Urology

出版年：2016

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