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内部出版物
在“
Elsevier电子期刊
”中,
命中:
12
条,耗时:小于0.01 秒
1.
Biochemical and biophysical studies of Trypanosoma cruzi phosphofructokinase as a target against Chagas disease
作者:
Dr Peter M Fernandes
;
BMBCh
a
;
peter.fernandes@ed.ac.uk" class="auth_mail" title="E-mail the corresponding author
;
James Kinkead
;
BSc
a
;
Iain
McNae
;
PhD
a
;
Prof Paul Michels
;
PhD
a
;
Prof Malcolm Walkinshaw
;
PhD
a
刊名:The Lancet
出版年:2016
2.
11¦Â-Hydroxysteroid dehydrogenase type 1 contributes to the balance between 7-keto- and 7-hydroxy-oxysterols in vivo
作者:
Tijana Miti?
a
;
Tijana.mitic@bristol.ac.uk
;
Steven Shave
b
;
s.shave@ed.ac.uk
;
Nina Semjonous
c
;
nina_sem@hotmail.com
;
Iain
McNae
b
;
Iain
.
McNae
@ed.ac.uk
;
Diego F. Cobice
a
;
d.f.cobice@sms.ed.ac.uk
;
Gareth G. Lavery
c
;
g.g.lavery@bham.ac.uk
;
Scott P. Webster
a
;
scott.webster@ed.ac.uk
;
Patrick W.F. Hadoke
a
;
patrick.hadoke@ed.ac.uk
;
Brian R. Walker
a
;
b.walker@ed.ac.uk
;
Ruth Andrew
a
;
r.andrew@ed.ac.uk
关键词:
7-Oxysterols
;
7¦Â-Hydroxycholesterol
;
7-Ketocholesterol
;
Glucocorticoids
;
11¦Â-Hydroxysteroid dehydrogenase 1
;
Corticosterone
刊名:Biochemical Pharmacology
出版年:2013
3.
Crystal Structures of Leishmania mexicana Phosphoglycerate Mutase Suggest a One-Metal Mechanism and a New Enzyme Subclass
作者:
Matthew W. Nowicki
;
Buabarn Kuaprasert
;
Iain
W.
McNae
;
Hugh P. Morgan
;
Marjorie M. Harding
;
Paul A.M. Michels
;
Linda A. Fothergill-Gilmore
;
Malcolm D. Walkinshaw
关键词:
phosphoglycerate mutase
;
Leishmania
;
parasite
;
glycolysis
;
crystal structure
刊名:Journal of Molecular Biology
出版年:2009
4.
The Crystal Structure of ATP-bound Phosphofructokinase from Trypanosoma brucei
作者:
Iain
W.
McNae
;
José
;
Martinez-Oyanedel
;
Jeffrey W. Keillor
;
Paul A.M. Michels
;
Linda A. Fothergill-Gilmore
;
Malcolm D. Walkinshaw
关键词:
phosphofructokinase
;
trypanosomes
;
X-ray crystallography
;
allostery
;
eukaryote
刊名:Journal of Molecular Biology
出版年:2009
5.
Structural and Functional Studies of the Biotin Protein Ligase from Aquifex aeolicus
作者:
Cecile M. Tron
;
Iain
W.
McNae
;
Margaret Nutley
;
David J. Clarke
;
Alan Cooper
;
Malcolm D. Walkinshaw
;
Robert L. Baxter
;
Dominic J. Campopiano
关键词:
biotin protein ligase
;
biotinylation
;
post-translation modification
;
X-ray crystallography
;
isothermal titration calorimetry
刊名:Journal of Molecular Biology
出版年:2009
6.
MeCP2 Binding to DNA Depends upon Hydration at Methyl-CpG
作者:
Kok Lian Ho
;
Iain
W.
McNae
;
Lars Schmiedeberg
;
Robert J. Klose
;
Adrian P. Bird
;
Malcolm D. Walkinshaw
关键词:
DNA
刊名:Molecular Cell
出版年:2008
7.
Design, synthesis and trypanocidal activity of lead compounds based on inhibitors of parasite glycolysis
作者:
Matthew W. Nowicki
;
Lindsay B. Tulloch
;
Liam Worralll
;
Iain
W.
McNae
;
Vé
;
ronique Hannaert
;
Paul A.M. Michels
;
Linda A. Fothergill-Gilmore
;
Malcolm D. Walkinshaw
;
Nicholas J. Turner
关键词:
Pyruvate kinase
;
Phosphofructokinase
;
Inhibitors
;
Leishmania
;
Trypanosome
;
Parasite
;
Drug development
;
Glycolysis
刊名:Bioorganic and Medicinal Chemistry
出版年:2008
8.
The First Crystal Structure of Phosphofructokinase from a Eukaryote: Trypanosoma brucei
作者:
José
;
Martinez-Oyanedel
;
Iain
W.
McNae
;
Matthew W. Nowicki
;
Jeffrey W. Keillor
;
Paul A.M. Michels
;
Linda A. Fothergill-Gilmore
;
Malcolm D. Walkinshaw
关键词:
eukaryote
;
phosphofructokinase
;
structure-based drug discovery
;
Trypanosoma brucei
;
X-ray crystallography
刊名:Journal of Molecular Biology
出版年:2007
9.
Crystallographic and Mass Spectrometric Characterisation of eIF4E with N
7
-alkylated Cap Derivatives
作者:
Christopher J. Brown
;
Iain
McNae
;
Peter M. Fischer
;
Malcolm D. Walkinshaw
关键词:
eIf4E
;
translation
;
mRNA
;
cap derivative
刊名:Journal of Molecular Biology
出版年:2007
10.
Differential Binding of Inhibitors to Active and Inactive CDK2 Provides Insights for Drug Design
作者:
George Kontopidis
;
Campbell McInnes
;
Sravan R. Pandalaneni
;
Iain
McNae
;
Darren Gibson
;
Mokdad Mezna
;
Mark Thomas
;
Gavin Wood
;
Shudong Wang
;
Malcolm D. Walkinshaw and Peter M. Fischer
刊名:Chemistry & Biology
出版年:2006
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